PDB entry 6j6y

View 6j6y on RCSB PDB site
Description: fgfr4 d2 - fab complex
Deposited on 2019-01-16, released 2019-08-07
The last revision was dated 2019-10-16, with a file datestamp of 2019-10-11.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fibroblast growth factor receptor 4
    Species: Homo sapiens [TaxId:9606]
    Gene: FGFR4, JTK2, TKF
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Fab heavy chain
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6J6Y
  • Chain 'C':
    Compound: Fab light chain
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6J6Y
  • Chain 'D':
    Compound: Fibroblast growth factor receptor 4
    Species: Homo sapiens [TaxId:9606]
    Gene: FGFR4, JTK2, TKF
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Fab heavy chain
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6J6Y
  • Chain 'F':
    Compound: Fab light chain
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6J6Y
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6j6yA (A:)
sypqqapywthpqrmekklhavpagntvkfrcpaagnptptirwlkdgqafhgenriggi
rlrhqhwslvmesvvpsdrgtytclvenavgsirynylldvler

    Sequence, based on observed residues (ATOM records):
    >6j6yA (A:)
pqqapywthpqrmekklhavpagntvkfrcpaagnptptirwlkdgqafhgenriggirl
rhqhwslvmesvvpsdrgtytclvenavgsirynylldvle

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6j6yB (B:)
klaatmkhlwfflllvaaprwvlsevqllesggglvqpggslrlscaasgftfsdyymsw
irqapgkglewvstisgsggstyyadsvkgrftisrdnskntlylqmnslraedtavyyc
arltayghvdswgqgtlvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvt
vswnsgaltsgvhtfpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrv
epkscdkth

    Sequence, based on observed residues (ATOM records):
    >6j6yB (B:)
evqllesggglvqpggslrlscaasgftfsdyymswirqapgkglewvstisgsggstyy
adsvkgrftisrdnskntlylqmnslraedtavyycarltayghvdswgqgtlvtvssas
tkgpsvfplapsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslss
vvtvpssslgtqtyicnvnhkpsntkvdkrvepks

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6j6yC (C:)
klaatmvlqtqvfislllwisgaygqsvltqppsasgtpgqrvtiscsgsssnigtntvn
wyqqlpgtapklliyrnyqrpsgvpdrfsgsksgtsaslaisglrsedeadyycaawdds
lsgphvvfgggtkltvlgqpkaapsvtlfppsseelqankatlvclisdfypgavtvawk
adsspvkagvetttpskqsnnkyaassylsltpeqwkshrsyscqvthegstvektvapt
ecs

    Sequence, based on observed residues (ATOM records):
    >6j6yC (C:)
qsvltqppsasgtpgqrvtiscsgsssnigtntvnwyqqlpgtapklliyrnyqrpsgvp
drfsgsksgtsaslaisglrsedeadyycaawddslsgphvvfgggtkltvlgqpkaaps
vtlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaa
ssylsltpeqwkshrsyscqvthegstvektvapt

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6j6yD (D:)
sypqqapywthpqrmekklhavpagntvkfrcpaagnptptirwlkdgqafhgenriggi
rlrhqhwslvmesvvpsdrgtytclvenavgsirynylldvler

    Sequence, based on observed residues (ATOM records):
    >6j6yD (D:)
ypqqapywthpqrmekklhavpagntvkfrcpaagnptptirwlkdgqafhgenriggir
lrhqhwslvmesvvpsdrgtytclvenavgsirynylldvl

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6j6yE (E:)
klaatmkhlwfflllvaaprwvlsevqllesggglvqpggslrlscaasgftfsdyymsw
irqapgkglewvstisgsggstyyadsvkgrftisrdnskntlylqmnslraedtavyyc
arltayghvdswgqgtlvtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvt
vswnsgaltsgvhtfpavlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrv
epkscdkth

    Sequence, based on observed residues (ATOM records):
    >6j6yE (E:)
evqllesggglvqpggslrlscaasgftfsdyymswirqapgkglewvstisgsggstyy
adsvkgrftisrdnskntlylqmnslraedtavyycarltayghvdswgqgtlvtvssas
tkgpsvfplapsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslss
vvtvpssslgtqtyicnvnhkpsntkvdkrvepksc

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6j6yF (F:)
klaatmvlqtqvfislllwisgaygqsvltqppsasgtpgqrvtiscsgsssnigtntvn
wyqqlpgtapklliyrnyqrpsgvpdrfsgsksgtsaslaisglrsedeadyycaawdds
lsgphvvfgggtkltvlgqpkaapsvtlfppsseelqankatlvclisdfypgavtvawk
adsspvkagvetttpskqsnnkyaassylsltpeqwkshrsyscqvthegstvektvapt
ecs

    Sequence, based on observed residues (ATOM records):
    >6j6yF (F:)
vltqppsasgtpgqrvtiscsgsssnigtntvnwyqqlpgtapklliyrnyqrpsgvpdr
fsgsksgtsaslaisglrsedeadyycaawddslsgphvvfgggtkltvlgqpkaapsvt
lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
ylsltpeqwkshrsyscqvthegstvektvapt