PDB entry 6j6m

View 6j6m on RCSB PDB site
Description: Co-crystal structure of BTK kinase domain with Zanubrutinib
Class: Transferase/Transferase inhibitor
Keywords: kinase, inhibitor, complex, Transferase-Transferase inhibitor complex
Deposited on 2019-01-15, released 2019-10-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-10-23, with a file datestamp of 2019-10-18.
Experiment type: XRAY
Resolution: 1.25 Å
R-factor: N/A
AEROSPACI score: 0.62 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase BTK
    Species: Homo sapiens [TaxId:9606]
    Gene: BTK, AGMX1, ATK, BPK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6j6ma_
  • Heterogens: BA0, IMD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6j6mA (A:)
gsgsweidpkdltflkelgtgqfgvvkygkwrgqydvaikmikegsmsedefieeakvmm
nlsheklvqlygvctkqrpifiiteymangcllnylremrhrfqtqqllemckdvceame
yleskqflhrdlaarnclvndqgvvkvsdfglsryvlddeytssvgskfpvrwsppevlm
yskfssksdiwafgvlmweiyslgkmpyerftnsetaehiaqglrlyrphlasekvytim
yscwhekaderptfkillsnildvmdees

    Sequence, based on observed residues (ATOM records): (download) 
    >6j6mA (A:)
gsweidpkdltflkelgtgqfgvvkygkwrgqydvaikmikegsmsedefieeakvmmnl
sheklvqlygvctkqrpifiiteymangcllnylremrhrfqtqqllemckdvceameyl
eskqflhrdlaarnclvndqgvvkvsdfglsryvlddeytssvgskfpvrwsppevlmys
kfssksdiwafgvlmweiyslgkmpyerftnsetaehiaqglrlyrphlasekvytimys
cwhekaderptfkillsnildvmdees