PDB entry 6j61

View 6j61 on RCSB PDB site
Description: crystal structure of thymidylate synthase, thy1, from thermus thermophilus having an extra c terminal domain
Deposited on 2019-01-12, released 2019-06-26
The last revision was dated 2019-07-03, with a file datestamp of 2019-06-28.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Flavin-dependent thymidylate synthase
    Species: Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) [TaxId:300852]
    Gene: thyX, TTHA1096
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Flavin-dependent thymidylate synthase
    Species: Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) [TaxId:300852]
    Gene: thyX, TTHA1096
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Flavin-dependent thymidylate synthase
    Species: Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) [TaxId:300852]
    Gene: thyX, TTHA1096
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Flavin-dependent thymidylate synthase
    Species: Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) [TaxId:300852]
    Gene: thyX, TTHA1096
    Database cross-references and differences (RAF-indexed):
  • Heterogens: FAD, PO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6j61A (A:)
megpltipvldkgfvrlvdqmgddraivqaarvsygegtktvredaalidylmrhrhtsp
femvvfkfhvkapifvarqwfrhrtasvneisgrysilkeefyepeafrkqakrnkqase
galldeealallrkvqqeaygayrallekgvaremarmvlplnlytefywkqdlhnlfhf
lklrlapeaqweirqyaraiaeivkervplawaafeehllegaflsrtelralrglltpe
vyekalsslglggsrlkealekvfgpgeal

    Sequence, based on observed residues (ATOM records):
    >6j61A (A:)
ltipvldkgfvrlvdqmgddraivqaarvsygegtktvredaalidylmrhrhtspfemv
vfkfhvkapifvarqwfrhrtasvneisgrysilkeefyepeafrkqllrkvqqeaygay
rallekgvaremarmvlplnlytefywkqdlhnlfhflklrlapeaqweirqyaraiaei
vkervplawaafeehllegaflsrtelralrglltpevyekalsslglggsrlkealekv
fg

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6j61B (B:)
megpltipvldkgfvrlvdqmgddraivqaarvsygegtktvredaalidylmrhrhtsp
femvvfkfhvkapifvarqwfrhrtasvneisgrysilkeefyepeafrkqakrnkqase
galldeealallrkvqqeaygayrallekgvaremarmvlplnlytefywkqdlhnlfhf
lklrlapeaqweirqyaraiaeivkervplawaafeehllegaflsrtelralrglltpe
vyekalsslglggsrlkealekvfgpgeal

    Sequence, based on observed residues (ATOM records):
    >6j61B (B:)
ltipvldkgfvrlvdqmgddraivqaarvsygegtktvredaalidylmrhrhtspfemv
vfkfhvkapifvarqwfrhrtasvneisgrysilkeefyepeafrllrkvqqeaygayra
llekgvaremarmvlplnlytefywkqdlhnlfhflklrlapeaqweirqyaraiaeivk
ervplawaafeehllegaflsrtelralrglltpevyekalsslglggsrlkealekvf

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6j61C (C:)
megpltipvldkgfvrlvdqmgddraivqaarvsygegtktvredaalidylmrhrhtsp
femvvfkfhvkapifvarqwfrhrtasvneisgrysilkeefyepeafrkqakrnkqase
galldeealallrkvqqeaygayrallekgvaremarmvlplnlytefywkqdlhnlfhf
lklrlapeaqweirqyaraiaeivkervplawaafeehllegaflsrtelralrglltpe
vyekalsslglggsrlkealekvfgpgeal

    Sequence, based on observed residues (ATOM records):
    >6j61C (C:)
ltipvldkgfvrlvdqmgddraivqaarvsygegtktvredaalidylmrhrhtspfemv
vfkfhvkapifvarqwfrhrtasvneisgrysilkeefyepeafrllrkvqqeaygayra
llekgvaremarmvlplnlytefywkqdlhnlfhflklrlapeaqweirqyaraiaeivk
ervplawaafeehllegaflsrtelralrglltpevyekalsslglggsrlkealekvfg

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6j61D (D:)
megpltipvldkgfvrlvdqmgddraivqaarvsygegtktvredaalidylmrhrhtsp
femvvfkfhvkapifvarqwfrhrtasvneisgrysilkeefyepeafrkqakrnkqase
galldeealallrkvqqeaygayrallekgvaremarmvlplnlytefywkqdlhnlfhf
lklrlapeaqweirqyaraiaeivkervplawaafeehllegaflsrtelralrglltpe
vyekalsslglggsrlkealekvfgpgeal

    Sequence, based on observed residues (ATOM records):
    >6j61D (D:)
ltipvldkgfvrlvdqmgddraivqaarvsygegtktvredaalidylmrhrhtspfemv
vfkfhvkapifvarqwfrhrtasvneisgrysilkeefyepeafrkqllrkvqqeaygay
rallekgvaremarmvlplnlytefywkqdlhnlfhflklrlapeaqweirqyaraiaei
vkervplawaafeehllegaflsrtelralrglltpevyekalsslglggsrlkealekv
fg