PDB entry 6j5l

View 6j5l on RCSB PDB site
Description: Crystal structure of Trk-A in complex with the Pan-Trk Kinase Inhibitor, compound 10e
Class: transferase
Keywords: Transferase inhibitor, TRANSFERASE
Deposited on 2019-01-11, released 2019-07-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-08-28, with a file datestamp of 2019-08-23.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: high affinity nerve growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: NTRK1, MTC, TRK, TRKA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P04629 (8-End)
      • expression tag (4-7)
    Domains in SCOPe 2.08: d6j5la1, d6j5la2
  • Heterogens: B9C, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6j5lA (A:)
gamgsgirvhhikrrdivlkwelgegafgkvflaechnllpeqdkmlvavkalkeasesa
rqdfqreaelltmlqhqhivrffgvctegrpllmvfeymrhgdlnrflrshgpdakllag
gedvapgplglgqllavasqvaagmvylaglhfvhrdlatrnclvgqglvvkigdfgmsr
diystdyyrvggrtmlpirwmppesilyrkfttesdvwsfgvvlweiftygkqpwyqlsn
teaidcitqgrelerpracppevyaimrgcwqrepqqrhsikdvharlqalaqappvyld
vlg

    Sequence, based on observed residues (ATOM records): (download) 
    >6j5lA (A:)
sgirvhhikrrdivlkwelgegafgkvflaechnldkmlvavkalkeasesarqdfqrea
elltmlqhqhivrffgvctegrpllmvfeymrhgdlnrflrshgpdakllaggedvapgp
lglgqllavasqvaagmvylaglhfvhrdlatrnclvgqglvvkigdfgiystdyyrvtm
lpirwmppesilyrkfttesdvwsfgvvlweiftygkqpwyqlsnteaidcitqgreler
pracppevyaimrgcwqrepqqrhsikdvharlqalaqappv