PDB entry 6j4v

View 6j4v on RCSB PDB site
Description: structural basis of tubulin detyrosination by vasohibins-svbp enzyme complex and functional implications
Deposited on 2019-01-10, released 2019-05-01
The last revision was dated 2020-01-15, with a file datestamp of 2020-01-10.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tubulinyl-Tyr carboxypeptidase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: VASH2, VASHL
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Small vasohibin-binding protein
    Species: Homo sapiens [TaxId:9606]
    Gene: SVBP, CCDC23
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8N300
      • engineered mutation (57)
  • Chain 'C':
    Compound: Tubulin alpha-1B chain
    Species: Homo sapiens [TaxId:9606]
    Gene: TUBA1B
    Database cross-references and differences (RAF-indexed):
    • Uniprot P68363 (Start-20)
      • engineered mutation (19)
  • Heterogens: PO4, GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6j4vA (A:)
gvlfhvnksgfpidshtwermwmhvakvhpkggemvgairnaaflakpsipqvpnyrlsm
tipdwlqaiqnymktlqynhtgtqffeirkmrplsglmetakemtreslpikcleavilg
iyltngqpsierfpisfktyfsgnyfhhvvlgiycngrygslgmsrraelmdkpltfrtl
sdlifdfedsykkylhtvkkvkiglyvphephsfqpiewkqlvlnvskmlradirkelek
yardmrmkilk

    Sequence, based on observed residues (ATOM records):
    >6j4vA (A:)
fhvnksgfpidshtwermwmhvakvhpkggemvgairnaaflakpsipqvpnyrlsmtip
dwlqaiqnymktlqynhtgtqffeirkmrplsglmetakemtreslpikcleavilgiyl
tngqpsierfpisfktyfsgnyfhhvvlgiycngrygslgmsrraelmdkpltfrtlsdl
ifdfedsykkylhtvkkvkiglyvphephsfqpiewkqlvlnvskmlradirkelekyar
dmrmki

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6j4vB (B:)
mdpparkektkvkesvsrvekakqksaqqelkqrqraeiyalnrvmteleqqqfdefskq
mqppge

    Sequence, based on observed residues (ATOM records):
    >6j4vB (B:)
qksaqqelkqrqraeiyalnrvmteleqqqfdefsk

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6j4vC (C:)
dyeevgvdsvegegeeegecy

    Sequence, based on observed residues (ATOM records):
    >6j4vC (C:)
egecy