PDB entry 6j4u

View 6j4u on RCSB PDB site
Description: structural basis of tubulin detyrosination by vasohibins-svbp enzyme complex and functional implications
Deposited on 2019-01-10, released 2019-05-01
The last revision was dated 2019-11-13, with a file datestamp of 2019-11-08.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tubulinyl-Tyr carboxypeptidase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: VASH1, KIAA1036, VASH
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7L8A9 (Start-250)
      • engineered mutation (14-15)
      • engineered mutation (22)
  • Chain 'B':
    Compound: Small vasohibin-binding protein
    Species: Homo sapiens [TaxId:9606]
    Gene: SVBP, CCDC23
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6j4uA (A:)
    gvpffvnrgglpvdshtwermwmhvakihpdgekvaqrirgatdlpkipipsvptfqpst
    pvperleavqryirelqynhtgtqffeikksrpltglmdlakemtkealpikcleavilg
    iyltnsmptlerfpisfktyfsgnyfrhivlgvnfagrygalgmsrredlmykppafrtl
    selvldfeaaygrcwhvlkkvklgqsvshdphsveqiewkhsvldverlgrddfrkeler
    hardmrlkigk
    

    Sequence, based on observed residues (ATOM records):
    >6j4uA (A:)
    fvnrgglpvdshtwermwmhvakihpdgekvaqrirgatdlpkipipsvptfqpstpvpe
    rleavqryirelqynhtgtqffeikksrpltglmdlakemtkealpikcleavilgiylt
    nsmptlerfpisfktyfsgnyfrhivlgvnfagrygalgmsrredlmykppafrtlselv
    ldfeaaygrcwhvlkkvklgqsvshdphsveqiewkhsvldverlgrddfrkelerhard
    mrlkigk
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6j4uB (B:)
    mdpparkektkvkesvsrvekakqksaqqelkqrqraeiyalnrvmteleqqqfdefckq
    mqppge
    

    Sequence, based on observed residues (ATOM records):
    >6j4uB (B:)
    qksaqqelkqrqraeiyalnrvmteleqq