PDB entry 6j4q

View 6j4q on RCSB PDB site
Description: structural basis of tubulin detyrosination by vasohibins-svbp enzyme complex and functional implications
Deposited on 2019-01-10, released 2019-05-01
The last revision was dated 2019-11-13, with a file datestamp of 2019-11-08.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tubulinyl-Tyr carboxypeptidase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: VASH2, VASHL
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Small vasohibin-binding protein
    Species: Homo sapiens [TaxId:9606]
    Gene: SVBP, CCDC23
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Tubulinyl-Tyr carboxypeptidase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: VASH2, VASHL
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Small vasohibin-binding protein
    Species: Homo sapiens [TaxId:9606]
    Gene: SVBP, CCDC23
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Tubulinyl-Tyr carboxypeptidase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: VASH2, VASHL
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Small vasohibin-binding protein
    Species: Homo sapiens [TaxId:9606]
    Gene: SVBP, CCDC23
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: Tubulinyl-Tyr carboxypeptidase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: VASH2, VASHL
    Database cross-references and differences (RAF-indexed):
  • Chain 'K':
    Compound: Small vasohibin-binding protein
    Species: Homo sapiens [TaxId:9606]
    Gene: SVBP, CCDC23
    Database cross-references and differences (RAF-indexed):
  • Heterogens: TQ8, GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6j4qA (A:)
gvlfhvnksgfpidshtwermwmhvakvhpkggemvgairnaaflakpsipqvpnyrlsm
tipdwlqaiqnymktlqynhtgtqffeirkmrplsglmetakemtreslpikcleavilg
iyltngqpsierfpisfktyfsgnyfhhvvlgiycngrygslgmsrraelmdkpltfrtl
sdlifdfedsykkylhtvkkvkiglyvphephsfqpiewkqlvlnvskmlradirkelek
yardmrmkilk

    Sequence, based on observed residues (ATOM records):
    >6j4qA (A:)
fhvnksgfpidshtwermwmhvakvhpkggemvgairnaaflakpsipqvpnyrlsmtip
dwlqaiqnymktlqynhtgtqffeirkmrplsglmetakemtreslpikcleavilgiyl
tngqpsierfpisfktyfsgnyfhhvvlgiycngrygslgmsrraelmdkpltfrtlsdl
ifdfedsykkylhtvkkvkiglyvphephsfqpiewkqlvlnvskmlradirkelekyar
dmrmkil

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6j4qB (B:)
mdpparkektkvkesvsrvekakqksaqqelkqrqraeiyalnrvmteleqqqfdefckq
mqppge

    Sequence, based on observed residues (ATOM records):
    >6j4qB (B:)
aqqelkqrqraeiyalnrvmteleqqqfdefck

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6j4qC (C:)
gvlfhvnksgfpidshtwermwmhvakvhpkggemvgairnaaflakpsipqvpnyrlsm
tipdwlqaiqnymktlqynhtgtqffeirkmrplsglmetakemtreslpikcleavilg
iyltngqpsierfpisfktyfsgnyfhhvvlgiycngrygslgmsrraelmdkpltfrtl
sdlifdfedsykkylhtvkkvkiglyvphephsfqpiewkqlvlnvskmlradirkelek
yardmrmkilk

    Sequence, based on observed residues (ATOM records):
    >6j4qC (C:)
fhvnksgfpidshtwermwmhvakvhpkggemvgairnaaflakpsipqvpnyrlsmtip
dwlqaiqnymktlqynhtgtqffeirkmrplsglmetakemtreslpikcleavilgiyl
tngqpsierfpisfktyfsgnyfhhvvlgiycngrygslgmsrraelmdkpltfrtlsdl
ifdfedsykkylhtvkkvkiglyvphephsfqpiewkqlvlnvskmlradirkelekyar
dmrmk

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6j4qD (D:)
mdpparkektkvkesvsrvekakqksaqqelkqrqraeiyalnrvmteleqqqfdefckq
mqppge

    Sequence, based on observed residues (ATOM records):
    >6j4qD (D:)
saqqelkqrqraeiyalnrvmteleqqqfdefck

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6j4qF (F:)
gvlfhvnksgfpidshtwermwmhvakvhpkggemvgairnaaflakpsipqvpnyrlsm
tipdwlqaiqnymktlqynhtgtqffeirkmrplsglmetakemtreslpikcleavilg
iyltngqpsierfpisfktyfsgnyfhhvvlgiycngrygslgmsrraelmdkpltfrtl
sdlifdfedsykkylhtvkkvkiglyvphephsfqpiewkqlvlnvskmlradirkelek
yardmrmkilk

    Sequence, based on observed residues (ATOM records):
    >6j4qF (F:)
fhvnksgfpidshtwermwmhvakvhpkggemvgairnaaflakpsipqvpnyrlsmtip
dwlqaiqnymktlqynhtgtqffeirkmrplsglmetakemtreslpikcleavilgiyl
tngqpsierfpisfktyfsgnyfhhvvlgiycngrygslgmsrraelmdkpltfrtlsdl
ifdfedsykkylhtvkkvkiglyvphephsfqpiewkqlvlnvskmlradirkelekyar
dmrmki

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6j4qG (G:)
mdpparkektkvkesvsrvekakqksaqqelkqrqraeiyalnrvmteleqqqfdefckq
mqppge

    Sequence, based on observed residues (ATOM records):
    >6j4qG (G:)
aqqelkqrqraeiyalnrvmteleqqqfdefc

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6j4qJ (J:)
gvlfhvnksgfpidshtwermwmhvakvhpkggemvgairnaaflakpsipqvpnyrlsm
tipdwlqaiqnymktlqynhtgtqffeirkmrplsglmetakemtreslpikcleavilg
iyltngqpsierfpisfktyfsgnyfhhvvlgiycngrygslgmsrraelmdkpltfrtl
sdlifdfedsykkylhtvkkvkiglyvphephsfqpiewkqlvlnvskmlradirkelek
yardmrmkilk

    Sequence, based on observed residues (ATOM records):
    >6j4qJ (J:)
fhvnksgfpidshtwermwmhvakvhpkggemvgairnaaflakpsipqvpnyrlsmtip
dwlqaiqnymktlqynhtgtqffeirkmrplsglmetakemtreslpikcleavilgiyl
tngqpsierfpisfktyfsgnyfhhvvlgiycngrygslgmsrraelmdkpltfrtlsdl
ifdfedsykkylhtvkkvkiglyvphephsfqpiewkqlvlnvskmlradirkelekyar
dmrmkil

  • Chain 'K':
    Sequence, based on SEQRES records:
    >6j4qK (K:)
mdpparkektkvkesvsrvekakqksaqqelkqrqraeiyalnrvmteleqqqfdefckq
mqppge

    Sequence, based on observed residues (ATOM records):
    >6j4qK (K:)
qelkqrqraeiyalnrvmteleqqqfdef