PDB entry 6j27

View 6j27 on RCSB PDB site
Description: crystal structure of the branched-chain polyamine synthase from thermus thermophilus (tth-bpsa) in complex with n4- aminopropylspermidine and 5'-methylthioadenosine
Deposited on 2018-12-31, released 2019-06-26
The last revision was dated 2019-10-23, with a file datestamp of 2019-10-18.
Experiment type: XRAY
Resolution: 1.66 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: N(4)-bis(aminopropyl)spermidine synthase
    Species: Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) [TaxId:262724]
    Gene: bpsA, TT_C0171
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: N(4)-bis(aminopropyl)spermidine synthase
    Species: Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) [TaxId:262724]
    Gene: bpsA, TT_C0171
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: N(4)-bis(aminopropyl)spermidine synthase
    Species: Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) [TaxId:262724]
    Gene: bpsA, TT_C0171
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: N(4)-bis(aminopropyl)spermidine synthase
    Species: Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) [TaxId:262724]
    Gene: bpsA, TT_C0171
    Database cross-references and differences (RAF-indexed):
  • Heterogens: FE, MTA, N4P, PGE, PEG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6j27A (A:)
mgsshhhhhhssglvprgshmvetagkgvsvnkealvqvaeevrratglpvgwrdvertl
galratrdlweavrlsrvplrflvpiweglarrgllrveegldllaevpaprpgeaacpa
cegrglvgerlpgraaerflawakerpeaiqdfdqgyvtpestlarvalawnwgdlegke
vlvlgdddltglaaaltglpkrvvvldadprivrfleraakaeglpleahvhdlreplpe
awvhafhtfftdpvegplglqafvgrgllalegegcagyvglthveaslakwadfqrfll
engavitelrdgfhvyenwgyieqmrawpwlpvkrrpekpwytsalirlellrradlena
rvegdlqdeeatty

    Sequence, based on observed residues (ATOM records):
    >6j27A (A:)
vnkealvqvaeevrratglpvgwrdvertlgalratrdlweavrlsrvplrflvpiwegl
arrgllrveegldllaevpaprpgeaacpacegrglvgerlpgraaerflawakerpeai
qdfdqgyvtpestlarvalawnwgdlegkevlvlgdddltglaaaltglpkrvvvldadp
rivrfleraakaeglpleahvhdlreplpeawvhafhtfftdpvegplglqafvgrglla
legegcagyvglthveaslakwadfqrfllengavitelrdgfhvyenwgyieqmrawpw
lpvkrrpekpwytsalirlellrradlenarvegdlqdeeatty

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6j27B (B:)
mgsshhhhhhssglvprgshmvetagkgvsvnkealvqvaeevrratglpvgwrdvertl
galratrdlweavrlsrvplrflvpiweglarrgllrveegldllaevpaprpgeaacpa
cegrglvgerlpgraaerflawakerpeaiqdfdqgyvtpestlarvalawnwgdlegke
vlvlgdddltglaaaltglpkrvvvldadprivrfleraakaeglpleahvhdlreplpe
awvhafhtfftdpvegplglqafvgrgllalegegcagyvglthveaslakwadfqrfll
engavitelrdgfhvyenwgyieqmrawpwlpvkrrpekpwytsalirlellrradlena
rvegdlqdeeatty

    Sequence, based on observed residues (ATOM records):
    >6j27B (B:)
vnkealvqvaeevrratglpvgwrdvertlgalratrdlweavrlsrvplrflvpiwegl
arrgllrveegldllaevpaprpgeaacpacegrglvgerlpgraaerflawakerpeai
qdfdqgyvtpestlarvalawnwgdlegkevlvlgdddltglaaaltglpkrvvvldadp
rivrfleraakaeglpleahvhdlreplpeawvhafhtfftdpvegplglqafvgrglla
legegcagyvglthveaslakwadfqrfllengavitelrdgfhvyenwgyieqmrawpw
lpvkrrpekpwytsalirlellrradlenarvegdlqdeeatty

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6j27C (C:)
mgsshhhhhhssglvprgshmvetagkgvsvnkealvqvaeevrratglpvgwrdvertl
galratrdlweavrlsrvplrflvpiweglarrgllrveegldllaevpaprpgeaacpa
cegrglvgerlpgraaerflawakerpeaiqdfdqgyvtpestlarvalawnwgdlegke
vlvlgdddltglaaaltglpkrvvvldadprivrfleraakaeglpleahvhdlreplpe
awvhafhtfftdpvegplglqafvgrgllalegegcagyvglthveaslakwadfqrfll
engavitelrdgfhvyenwgyieqmrawpwlpvkrrpekpwytsalirlellrradlena
rvegdlqdeeatty

    Sequence, based on observed residues (ATOM records):
    >6j27C (C:)
nkealvqvaeevrratglpvgwrdvertlgalratrdlweavrlsrvplrflvpiwegla
rrgllrveegldllaevpaprpgeaacpacegrglvgerlpgraaerflawakerpeaiq
dfdqgyvtpestlarvalawnwgdlegkevlvlgdddltglaaaltglpkrvvvldadpr
ivrfleraakaeglpleahvhdlreplpeawvhafhtfftdpvegplglqafvgrgllal
egegcagyvglthveaslakwadfqrfllengavitelrdgfhvyenwgyieqmrawpwl
pvkrrpekpwytsalirlellrradlenarvegdlqdeeatty

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6j27D (D:)
mgsshhhhhhssglvprgshmvetagkgvsvnkealvqvaeevrratglpvgwrdvertl
galratrdlweavrlsrvplrflvpiweglarrgllrveegldllaevpaprpgeaacpa
cegrglvgerlpgraaerflawakerpeaiqdfdqgyvtpestlarvalawnwgdlegke
vlvlgdddltglaaaltglpkrvvvldadprivrfleraakaeglpleahvhdlreplpe
awvhafhtfftdpvegplglqafvgrgllalegegcagyvglthveaslakwadfqrfll
engavitelrdgfhvyenwgyieqmrawpwlpvkrrpekpwytsalirlellrradlena
rvegdlqdeeatty

    Sequence, based on observed residues (ATOM records):
    >6j27D (D:)
vnkealvqvaeevrratglpvgwrdvertlgalratrdlweavrlsrvplrflvpiwegl
arrgllrveegldllaevpaprpgeaacpacegrglvgerlpgraaerflawakerpeai
qdfdqgyvtpestlarvalawnwgdlegkevlvlgdddltglaaaltglpkrvvvldadp
rivrfleraakaeglpleahvhdlreplpeawvhafhtfftdpvegplglqafvgrglla
legegcagyvglthveaslakwadfqrfllengavitelrdgfhvyenwgyieqmrawpw
lpvkrrpekpwytsalirlellrradlenarvegdlqdeeatty