PDB entry 6j10

View 6j10 on RCSB PDB site
Description: Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly
Class: viral protein
Keywords: Hepatitis B virus, Ciclopirox, Capsid assembly inhibitor, VIRAL PROTEIN
Deposited on 2018-12-27, released 2019-04-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-29, with a file datestamp of 2019-05-24.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: capsid protein
    Species: Hepatitis B virus genotype D subtype adw [TaxId:10419]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03147 (0-End)
      • engineered mutation (131)
    Domains in SCOPe 2.08: d6j10a_
  • Chain 'B':
    Compound: capsid protein
    Species: Hepatitis B virus genotype D subtype adw [TaxId:10419]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03147 (0-End)
      • engineered mutation (131)
    Domains in SCOPe 2.08: d6j10b_
  • Chain 'C':
    Compound: capsid protein
    Species: Hepatitis B virus genotype D subtype adw [TaxId:10419]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03147 (0-End)
      • engineered mutation (131)
    Domains in SCOPe 2.08: d6j10c_
  • Chain 'D':
    Compound: capsid protein
    Species: Hepatitis B virus genotype D subtype adw [TaxId:10419]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03147 (0-End)
      • engineered mutation (131)
    Domains in SCOPe 2.08: d6j10d_
  • Chain 'E':
    Compound: capsid protein
    Species: Hepatitis B virus genotype D subtype adw [TaxId:10419]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03147 (0-End)
      • engineered mutation (131)
    Domains in SCOPe 2.08: d6j10e_
  • Chain 'F':
    Compound: capsid protein
    Species: Hepatitis B virus genotype D subtype adw [TaxId:10419]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03147 (0-End)
      • engineered mutation (131)
    Domains in SCOPe 2.08: d6j10f_
  • Heterogens: B4O, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6j10A (A:)
mdidpykefgatvellsflpsdffpsvrdlldtaaalyrdalespehcsphhtalrqail
cwgdlmtlatwvgtnledpasrdlvvsyvntnvglkfrqllwfhiscltfgretvleylv
sfgvwirtppaarppnapilstlpettvv

    Sequence, based on observed residues (ATOM records): (download) 
    >6j10A (A:)
mdidpykefgatvellsflpsdffpsvrdlldtaaalyrdalespehcsphhtalrqail
cwgdlmtlatwvgtnledpasrdlvvsyvntnvglkfrqllwfhiscltfgretvleylv
sfgvwirtppaarppnapils

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6j10B (B:)
mdidpykefgatvellsflpsdffpsvrdlldtaaalyrdalespehcsphhtalrqail
cwgdlmtlatwvgtnledpasrdlvvsyvntnvglkfrqllwfhiscltfgretvleylv
sfgvwirtppaarppnapilstlpettvv

    Sequence, based on observed residues (ATOM records): (download) 
    >6j10B (B:)
mdidpykefgatvellsflpsdffpsvrdlldtaaalyrdalespehcsphhtalrqail
cwgdlmtlatwvgtnledpasrdlvvsyvntnvglkfrqllwfhiscltfgretvleylv
sfgvwirtppaarppnapils

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6j10C (C:)
mdidpykefgatvellsflpsdffpsvrdlldtaaalyrdalespehcsphhtalrqail
cwgdlmtlatwvgtnledpasrdlvvsyvntnvglkfrqllwfhiscltfgretvleylv
sfgvwirtppaarppnapilstlpettvv

    Sequence, based on observed residues (ATOM records): (download) 
    >6j10C (C:)
mdidpykefgatvellsflpsdffpsvrdlldtaaalyrdalespehcsphhtalrqail
cwgdlmtlatwvgtnledpasrdlvvsyvntnvglkfrqllwfhiscltfgretvleylv
sfgvwirtppaarppnapils

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6j10D (D:)
mdidpykefgatvellsflpsdffpsvrdlldtaaalyrdalespehcsphhtalrqail
cwgdlmtlatwvgtnledpasrdlvvsyvntnvglkfrqllwfhiscltfgretvleylv
sfgvwirtppaarppnapilstlpettvv

    Sequence, based on observed residues (ATOM records): (download) 
    >6j10D (D:)
mdidpykefgatvellsflpsdffpsvrdlldtaaalyrdalespehcsphhtalrqail
cwgdlmtlatwvgtnledpasrdlvvsyvntnvglkfrqllwfhiscltfgretvleylv
sfgvwirtppaarppnapils

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6j10E (E:)
mdidpykefgatvellsflpsdffpsvrdlldtaaalyrdalespehcsphhtalrqail
cwgdlmtlatwvgtnledpasrdlvvsyvntnvglkfrqllwfhiscltfgretvleylv
sfgvwirtppaarppnapilstlpettvv

    Sequence, based on observed residues (ATOM records): (download) 
    >6j10E (E:)
mdidpykefgatvellsflpsdffpsvrdlldtaaalyrdalespehcsphhtalrqail
cwgdlmtlatwvgtnledpasrdlvvsyvntnvglkfrqllwfhiscltfgretvleylv
sfgvwirtppaarppnapils

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6j10F (F:)
mdidpykefgatvellsflpsdffpsvrdlldtaaalyrdalespehcsphhtalrqail
cwgdlmtlatwvgtnledpasrdlvvsyvntnvglkfrqllwfhiscltfgretvleylv
sfgvwirtppaarppnapilstlpettvv

    Sequence, based on observed residues (ATOM records): (download) 
    >6j10F (F:)
mdidpykefgatvellsflpsdffpsvrdlldtaaalyrdalespehcsphhtalrqail
cwgdlmtlatwvgtnledpasrdlvvsyvntnvglkfrqllwfhiscltfgretvleylv
sfgvwirtppaarppnapils