PDB entry 6j0u

View 6j0u on RCSB PDB site
Description: crystal structure of the acyltransferase domain from the third module of the ansamitocin polyketide synthase
Deposited on 2018-12-26, released 2019-12-18
The last revision was dated 2020-05-20, with a file datestamp of 2020-05-15.
Experiment type: XRAY
Resolution: 1.79 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Type 1 modular polyketide synthase
    Species: Actinosynnema pretiosum subsp. auranticum [TaxId:42198]
    Gene: AsmAT3
    Database cross-references and differences (RAF-indexed):
    • PDB 6J0U
  • Chain 'B':
    Compound: Type 1 modular polyketide synthase
    Species: Actinosynnema pretiosum subsp. auranticum [TaxId:42198]
    Gene: AsmAT3
    Database cross-references and differences (RAF-indexed):
    • PDB 6J0U
  • Chain 'C':
    Compound: Type 1 modular polyketide synthase
    Species: Actinosynnema pretiosum subsp. auranticum [TaxId:42198]
    Gene: AsmAT3
    Database cross-references and differences (RAF-indexed):
    • PDB 6J0U
  • Chain 'D':
    Compound: Type 1 modular polyketide synthase
    Species: Actinosynnema pretiosum subsp. auranticum [TaxId:42198]
    Gene: AsmAT3
    Database cross-references and differences (RAF-indexed):
    • PDB 6J0U
  • Heterogens: PO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6j0uA (A:)
mgsshhhhhhssglvprgshmapvpvvvsgattaglrdapvpvpvpvpvpvavsgattag
lraqaarlaghlrerpalgpeavarplllsraqrerravvvaadrdslltgldalaggea
gprlasgaadvtgrvvlvfpgqgahwtgvaerlwreapvfadsmarcadvlrdlagwelr
evlvdpvalervdvlqpvsfavvvslaalwasvgvrpdavvghsqgevaaahvagaltla
eaarivvlrsaliarelsgrgamltvvadvervtallagfegrvcvaavngpasvtvsge
dgavrefervlsarrmlrwrlpgvdfaghspqvdalraellaalgdiasrepeipllstv
tgepatrldaehwyrnlrepvrfadavtalldrghrvfvevsphpvlttsvvdlaaphrt
avvgtlrrdeggldrfllsaaelhvrgvpvdlarhagagtaevpttvfq

    Sequence, based on observed residues (ATOM records):
    >6j0uA (A:)
vpvpvpvavsgattaglraqaarlaghlrerpalgpeavarplllsraqrerravvvaad
rdslltgldalaggeagprlasgaadvtgrvvlvfpgqgahwtgvaerlwreapvfadsm
arcadvlrdlagwelrevlvdpvalervdvlqpvsfavvvslaalwasvgvrpdavvghs
qgevaaahvagaltlaeaarivvlrsaliarelsgrgamltvvadvervtallagfegrv
cvaavngpasvtvsgedgavrefervlsarrmlrwrlpgvdfaghspqvdalraellaal
gdiasrepeipllstvtgepatrldaehwyrnlrepvrfadavtalldrghrvfvevsph
pvlttsvvdlaaphrtavvgtlrrdeggldrfllsaaelhvrgvpvdlarhagagtaev

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6j0uB (B:)
mgsshhhhhhssglvprgshmapvpvvvsgattaglrdapvpvpvpvpvpvavsgattag
lraqaarlaghlrerpalgpeavarplllsraqrerravvvaadrdslltgldalaggea
gprlasgaadvtgrvvlvfpgqgahwtgvaerlwreapvfadsmarcadvlrdlagwelr
evlvdpvalervdvlqpvsfavvvslaalwasvgvrpdavvghsqgevaaahvagaltla
eaarivvlrsaliarelsgrgamltvvadvervtallagfegrvcvaavngpasvtvsge
dgavrefervlsarrmlrwrlpgvdfaghspqvdalraellaalgdiasrepeipllstv
tgepatrldaehwyrnlrepvrfadavtalldrghrvfvevsphpvlttsvvdlaaphrt
avvgtlrrdeggldrfllsaaelhvrgvpvdlarhagagtaevpttvfq

    Sequence, based on observed residues (ATOM records):
    >6j0uB (B:)
vpvpvpvavsgattaglraqaarlaghlrerpalgpeavarplllsraqrerravvvaad
rdslltgldalaggeagprlasgaadvtgrvvlvfpgqgahwtgvaerlwreapvfadsm
arcadvlrdlagwelrevlvdpvalervdvlqpvsfavvvslaalwasvgvrpdavvghs
qgevaaahvagaltlaeaarivvlrsaliarelsgrgamltvvadvervtallagfegrv
cvaavngpasvtvsgedgavrefervlsarrmlrwrlpgvdfaghspqvdalraellaal
gdiasrepeipllstvtgepatrldaehwyrnlrepvrfadavtalldrghrvfvevsph
pvlttsvvdlaaphrtavvgtlrrdeggldrfllsaaelhvrgvpvdlarhagagtaevp

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6j0uC (C:)
mgsshhhhhhssglvprgshmapvpvvvsgattaglrdapvpvpvpvpvpvavsgattag
lraqaarlaghlrerpalgpeavarplllsraqrerravvvaadrdslltgldalaggea
gprlasgaadvtgrvvlvfpgqgahwtgvaerlwreapvfadsmarcadvlrdlagwelr
evlvdpvalervdvlqpvsfavvvslaalwasvgvrpdavvghsqgevaaahvagaltla
eaarivvlrsaliarelsgrgamltvvadvervtallagfegrvcvaavngpasvtvsge
dgavrefervlsarrmlrwrlpgvdfaghspqvdalraellaalgdiasrepeipllstv
tgepatrldaehwyrnlrepvrfadavtalldrghrvfvevsphpvlttsvvdlaaphrt
avvgtlrrdeggldrfllsaaelhvrgvpvdlarhagagtaevpttvfq

    Sequence, based on observed residues (ATOM records):
    >6j0uC (C:)
vpvpvpvavsgattaglraqaarlaghlrerpalgpeavarplllsraqrerravvvaad
rdslltgldalaggeagprlasgaadvtgrvvlvfpgqgahwtgvaerlwreapvfadsm
arcadvlrdlagwelrevlvdpvalervdvlqpvsfavvvslaalwasvgvrpdavvghs
qgevaaahvagaltlaeaarivvlrsaliarelsgrgamltvvadvervtallagfegrv
cvaavngpasvtvsgedgavrefervlsarrmlrwrlpgvdfaghspqvdalraellaal
gdiasrepeipllstvtgepatrldaehwyrnlrepvrfadavtalldrghrvfvevsph
pvlttsvvdlaaphrtavvgtlrrdeggldrfllsaaelhvrgvpvdlarhagagtaev

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6j0uD (D:)
mgsshhhhhhssglvprgshmapvpvvvsgattaglrdapvpvpvpvpvpvavsgattag
lraqaarlaghlrerpalgpeavarplllsraqrerravvvaadrdslltgldalaggea
gprlasgaadvtgrvvlvfpgqgahwtgvaerlwreapvfadsmarcadvlrdlagwelr
evlvdpvalervdvlqpvsfavvvslaalwasvgvrpdavvghsqgevaaahvagaltla
eaarivvlrsaliarelsgrgamltvvadvervtallagfegrvcvaavngpasvtvsge
dgavrefervlsarrmlrwrlpgvdfaghspqvdalraellaalgdiasrepeipllstv
tgepatrldaehwyrnlrepvrfadavtalldrghrvfvevsphpvlttsvvdlaaphrt
avvgtlrrdeggldrfllsaaelhvrgvpvdlarhagagtaevpttvfq

    Sequence, based on observed residues (ATOM records):
    >6j0uD (D:)
vpvpvpvavsgattaglraqaarlaghlrerpalgpeavarplllsraqrerravvvaad
rdslltgldalaggeagprlasgaadvtgrvvlvfpgqgahwtgvaerlwreapvfadsm
arcadvlrdlagwelrevlvdpvalervdvlqpvsfavvvslaalwasvgvrpdavvghs
qgevaaahvagaltlaeaarivvlrsaliarelsgrgamltvvadvervtallagfegrv
cvaavngpasvtvsgedgavrefervlsarrmlrwrlpgvdfaghspqvdalraellaal
gdiasrepeipllstvtgepatrldaehwyrnlrepvrfadavtalldrghrvfvevsph
pvlttsvvdlaaphrtavvgtlrrdeggldrfllsaaelhvrgvpvdlarhagagtaevp