PDB entry 6iyw

View 6iyw on RCSB PDB site
Description: Crystal sturucture of L,D-transpeptidase LdtMt2 from Mycobacterium tuberculosis in complex with Imipenem adduct
Class: transferase
Keywords: LD-TRANSPEPTIDASE, PEPTIDOGLYCAN SYNTHESIS ENZYME, beta-lactam binding, TRANSFERASE
Deposited on 2018-12-17, released 2019-02-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-02-27, with a file datestamp of 2019-02-22.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: L,D-transpeptidase 2
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: ldtB, lppS, Rv2518c, RVBD_2518c, P425_02624
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6iywa1, d6iywa2
  • Chain 'B':
    Compound: L,D-transpeptidase 2
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: ldtB, lppS, Rv2518c, RVBD_2518c, P425_02624
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6iywb1, d6iywb2
  • Chain 'C':
    Compound: L,D-transpeptidase 2
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: ldtB, lppS, Rv2518c, RVBD_2518c, P425_02624
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6iywc1, d6iywc2
  • Chain 'D':
    Compound: L,D-transpeptidase 2
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: ldtB, lppS, Rv2518c, RVBD_2518c, P425_02624
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6iywd1, d6iywd2
  • Chain 'E':
    Compound: L,D-transpeptidase 2
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: ldtB, lppS, Rv2518c, RVBD_2518c, P425_02624
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6iywe1, d6iywe2
  • Chain 'F':
    Compound: L,D-transpeptidase 2
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: ldtB, lppS, Rv2518c, RVBD_2518c, P425_02624
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6iywf1, d6iywf2
  • Heterogens: IM2, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6iywA (A:)
snaqltfqtsspahltmpyvmpgdgevvgvgepvairfdeniadrgaaekaikittnppv
egafywlnnrevrwrpehfwkpgtavdvavntygvdlgegmfgednvqthftigdeviat
addntkiltvrvngevvksmptsmgkdstptangiyivgsrykhiimdsstygvpvnspn
gyrtdvdwatqisysgvfvhsapwsvgaqghtntshgclnvspsnaqwfydhvkrgdive
vvntvggtlpgidglgdwnipwdqwragnaka

    Sequence, based on observed residues (ATOM records): (download) 
    >6iywA (A:)
ltfqtsspahltmpyvmpgdgevvgvgepvairfdeniadrgaaekaikittnppvegaf
ywlnnrevrwrpehfwkpgtavdvavntygvdlgegmfgednvqthftigdeviataddn
tkiltvrvngevvksmptsmgkdstptangiyivgsrykhiimdsstygvpvnspngyrt
dvdwatqisysgvfvhsapwsvgaqghtntshgclnvspsnaqwfydhvkrgdivevvnt
vggtlpgidglgdwnipwdqwragna

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6iywB (B:)
snaqltfqtsspahltmpyvmpgdgevvgvgepvairfdeniadrgaaekaikittnppv
egafywlnnrevrwrpehfwkpgtavdvavntygvdlgegmfgednvqthftigdeviat
addntkiltvrvngevvksmptsmgkdstptangiyivgsrykhiimdsstygvpvnspn
gyrtdvdwatqisysgvfvhsapwsvgaqghtntshgclnvspsnaqwfydhvkrgdive
vvntvggtlpgidglgdwnipwdqwragnaka

    Sequence, based on observed residues (ATOM records): (download) 
    >6iywB (B:)
ltfqtsspahltmpyvmpgdgevvgvgepvairfdeniadrgaaekaikittnppvegaf
ywlnnrevrwrpehfwkpgtavdvavntygvdlgegmfgednvqthftigdeviataddn
tkiltvrvngevvksmptsmgkdstptangiyivgsrykhiimdsstygvpvnspngyrt
dvdwatqisysgvfvhsapwsvgaqghtntshgclnvspsnaqwfydhvkrgdivevvnt
vggtlpgidglgdwnipwdqwragna

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6iywC (C:)
snaqltfqtsspahltmpyvmpgdgevvgvgepvairfdeniadrgaaekaikittnppv
egafywlnnrevrwrpehfwkpgtavdvavntygvdlgegmfgednvqthftigdeviat
addntkiltvrvngevvksmptsmgkdstptangiyivgsrykhiimdsstygvpvnspn
gyrtdvdwatqisysgvfvhsapwsvgaqghtntshgclnvspsnaqwfydhvkrgdive
vvntvggtlpgidglgdwnipwdqwragnaka

    Sequence, based on observed residues (ATOM records): (download) 
    >6iywC (C:)
ltfqtsspahltmpyvmpgdgevvgvgepvairfdeniadrgaaekaikittnppvegaf
ywlnnrevrwrpehfwkpgtavdvavntygvdlgegmfgednvqthftigdeviataddn
tkiltvrvngevvksmptsmgkdstptangiyivgsrykhiimdsstygvpvnspngyrt
dvdwatqisysgvfvhsapwsvgaqghtntshgclnvspsnaqwfydhvkrgdivevvnt
vggtlpgidglgdwnipwdqwragnak

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6iywD (D:)
snaqltfqtsspahltmpyvmpgdgevvgvgepvairfdeniadrgaaekaikittnppv
egafywlnnrevrwrpehfwkpgtavdvavntygvdlgegmfgednvqthftigdeviat
addntkiltvrvngevvksmptsmgkdstptangiyivgsrykhiimdsstygvpvnspn
gyrtdvdwatqisysgvfvhsapwsvgaqghtntshgclnvspsnaqwfydhvkrgdive
vvntvggtlpgidglgdwnipwdqwragnaka

    Sequence, based on observed residues (ATOM records): (download) 
    >6iywD (D:)
tfqtsspahltmpyvmpgdgevvgvgepvairfdeniadrgaaekaikittnppvegafy
wlnnrevrwrpehfwkpgtavdvavntygvdlgegmfgednvqthftigdeviataddnt
kiltvrvngevvksmptsmgkdstptangiyivgsrykhiimdsstygvpvnspngyrtd
vdwatqisysgvfvhsapwsvgaqghtntshgclnvspsnaqwfydhvkrgdivevvntv
ggtlpgidglgdwnipwdqwragn

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6iywE (E:)
snaqltfqtsspahltmpyvmpgdgevvgvgepvairfdeniadrgaaekaikittnppv
egafywlnnrevrwrpehfwkpgtavdvavntygvdlgegmfgednvqthftigdeviat
addntkiltvrvngevvksmptsmgkdstptangiyivgsrykhiimdsstygvpvnspn
gyrtdvdwatqisysgvfvhsapwsvgaqghtntshgclnvspsnaqwfydhvkrgdive
vvntvggtlpgidglgdwnipwdqwragnaka

    Sequence, based on observed residues (ATOM records): (download) 
    >6iywE (E:)
tfqtsspahltmpyvmpgdgevvgvgepvairfdeniadrgaaekaikittnppvegafy
wlnnrevrwrpehfwkpgtavdvavntygvdlgegmfgednvqthftigdeviataddnt
kiltvrvngevvksmptsmgkdstptangiyivgsrykhiimdsstygvpvnspngyrtd
vdwatqisysgvfvhsapwsvgaqghtntshgclnvspsnaqwfydhvkrgdivevvntv
ggtlpgidglgdwnipwdqwragn

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6iywF (F:)
snaqltfqtsspahltmpyvmpgdgevvgvgepvairfdeniadrgaaekaikittnppv
egafywlnnrevrwrpehfwkpgtavdvavntygvdlgegmfgednvqthftigdeviat
addntkiltvrvngevvksmptsmgkdstptangiyivgsrykhiimdsstygvpvnspn
gyrtdvdwatqisysgvfvhsapwsvgaqghtntshgclnvspsnaqwfydhvkrgdive
vvntvggtlpgidglgdwnipwdqwragnaka

    Sequence, based on observed residues (ATOM records): (download) 
    >6iywF (F:)
tfqtsspahltmpyvmpgdgevvgvgepvairfdeniadrgaaekaikittnppvegafy
wlnnrevrwrpehfwkpgtavdvavntygvdlgegmfgednvqthftigdeviataddnt
kiltvrvngevvksmptsmgkdstptangiyivgsrykhiimdsstygvpvnspngyrtd
vdwatqisysgvfvhsapwsvgaqghtntshgclnvspsnaqwfydhvkrgdivevvntv
ggtlpgidglgdwnipwdqwragn