PDB entry 6iyb

View 6iyb on RCSB PDB site
Description: Structure of human ORP1 ANK - Rab7 complex
Class: transport protein
Keywords: oxysterol-binding protein, ORP1, membrane contact site, Rab7, Ankyrin repeat, cholesterol, RILP, Late endosome, TRANSPORT PROTEIN
Deposited on 2018-12-14, released 2019-03-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-03-13, with a file datestamp of 2019-03-08.
Experiment type: XRAY
Resolution: 2.09 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ras-related protein Rab-7a
    Species: Homo sapiens [TaxId:9606]
    Gene: RAB7A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51149
      • engineered mutation (71)
    Domains in SCOPe 2.08: d6iyba_
  • Chain 'B':
    Compound: Oxysterol-binding protein-related protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: OSBPL1A
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9BXW6 (6-End)
      • expression tag (5)
    Domains in SCOPe 2.08: d6iybb1, d6iybb2
  • Chain 'C':
    Compound: Ras-related protein Rab-7a
    Species: Homo sapiens [TaxId:9606]
    Gene: RAB7A
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51149
      • engineered mutation (71)
    Domains in SCOPe 2.08: d6iybc_
  • Chain 'D':
    Compound: Oxysterol-binding protein-related protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: OSBPL1A
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9BXW6 (6-End)
      • expression tag (4-5)
    Domains in SCOPe 2.08: d6iybd1, d6iybd2
  • Heterogens: GTP, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6iybA (A:)
gsamgstsrkkvllkviilgdsgvgktslmnqyvnkkfsnqykatigadfltkevmvddr
lvtmqiwdtaglerfqsgvafyrgadccvlvfdvtapntfktldswrdefliqasprdpe
nfpfvvlgnkidlenrqvatkraqawcysknnipyfetsakeainveqafqtiarnalkq
etevelynefpepikldkn

    Sequence, based on observed residues (ATOM records): (download) 
    >6iybA (A:)
vllkviilgdsgvgktslmnqyvnkkfsnqykatigadfltkevmvddrlvtmqiwdtag
lerfqsgvafyrgadccvlvfdvtapntfktldswrdefliqasprdpenfpfvvlgnki
dlenrqvatkraqawcysknnipyfetsakeainveqafqtiarnalkqet

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6iybB (B:)
gsamgsaeqqllhharngnaeevrqlletmarneviadinckgrsksnlgwtplhlacyf
ghrqvvqdllkagaevnvlndmgdtplhraaftgrkelvmllleynadttivngsgqtak
evthaeeirsmleavertqqrkleelllaaareg

    Sequence, based on observed residues (ATOM records): (download) 
    >6iybB (B:)
saeqqllhharngnaeevrqlletmarneviadinckgrsksnlgwtplhlacyfghrqv
vqdllkagaevnvlndmgdtplhraaftgrkelvmllleynadttivngsgqtakevtha
eeirsmleavertqq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6iybC (C:)
gsamgstsrkkvllkviilgdsgvgktslmnqyvnkkfsnqykatigadfltkevmvddr
lvtmqiwdtaglerfqsgvafyrgadccvlvfdvtapntfktldswrdefliqasprdpe
nfpfvvlgnkidlenrqvatkraqawcysknnipyfetsakeainveqafqtiarnalkq
etevelynefpepikldkn

    Sequence, based on observed residues (ATOM records): (download) 
    >6iybC (C:)
vllkviilgdsgvgktslmnqyvnkkfsnqykatigadfltkevmvddrlvtmqiwdtag
lerfqsgvafyrgadccvlvfdvtapntfktldswrdefliqasprdpenfpfvvlgnki
dlenrqvatkraqawcysknnipyfetsakeainveqafqtiarnalkqet

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6iybD (D:)
gsamgsaeqqllhharngnaeevrqlletmarneviadinckgrsksnlgwtplhlacyf
ghrqvvqdllkagaevnvlndmgdtplhraaftgrkelvmllleynadttivngsgqtak
evthaeeirsmleavertqqrkleelllaaareg

    Sequence, based on observed residues (ATOM records): (download) 
    >6iybD (D:)
gsaeqqllhharngnaeevrqlletmarneviadinckgrsksnlgwtplhlacyfghrq
vvqdllkagaevnvlndmgdtplhraaftgrkelvmllleynadttivngsgqtakevth
aeeirsmleavertq