PDB entry 6iy9

View 6iy9 on RCSB PDB site
Description: crystal structure of aminoglycoside 7"-phoshotransferase-ia (aph(7")- ia/hyg) from streptomyces hygroscopicus complexed with hygromycin b
Deposited on 2018-12-14, released 2019-09-11
The last revision was dated 2019-11-20, with a file datestamp of 2019-11-15.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hygromycin-B 7''-O-kinase
    Species: Streptomyces hygroscopicus [TaxId:1912]
    Gene: hyg
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09979
      • engineered mutation (62)
  • Chain 'B':
    Compound: Hygromycin-B 7''-O-kinase
    Species: Streptomyces hygroscopicus [TaxId:1912]
    Gene: hyg
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09979
      • engineered mutation (62)
  • Heterogens: HY0, NHE, FLC, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6iy9A (A:)
mtqeslllldridsddsyaslrndqefweplarraleelglpvppvlrvpgestnpvlvg
epgpviklfgehwcgpeslaseseayavladapvpvprllgrgelrpgtgawpwpylvms
rmtgttwrsamdgttdrnallalarelgrvlgrlhrvpltgntvltphsevfpellrerr
aatvedhrgwgylsprlldrledwlpdvdtllagreprfvhgdlhgtnifvdlaatevtg
ivdftdvyagdsryslvqlhlnafrgdreilaalldgaqwkrtedfarellaftflhdfe
vfeetpldlsgftdpeelaqflwgppdtapgalehhhhhh

    Sequence, based on observed residues (ATOM records):
    >6iy9A (A:)
qeslllldridsddsyaslrndqefweplarraleelglpvppvlrvpgestnpvlvgep
gpviklfgehwcgpeslaseseayavladapvpvprllgrgelrpgtgawpwpylvmsrm
tgttwrsamdgttdrnallalarelgrvlgrlhrvpltgntvltphsevfpellrerraa
tvedhrgwgylsprlldrledwlpdvdtllagreprfvhgdlhgtnifvdlaatevtgiv
dftdvyagdsryslvqlhlnafrgdreilaalldgaqwkrtedfarellaftflhdfevf
eetpldlsgftdpeelaqflwgppd

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6iy9B (B:)
mtqeslllldridsddsyaslrndqefweplarraleelglpvppvlrvpgestnpvlvg
epgpviklfgehwcgpeslaseseayavladapvpvprllgrgelrpgtgawpwpylvms
rmtgttwrsamdgttdrnallalarelgrvlgrlhrvpltgntvltphsevfpellrerr
aatvedhrgwgylsprlldrledwlpdvdtllagreprfvhgdlhgtnifvdlaatevtg
ivdftdvyagdsryslvqlhlnafrgdreilaalldgaqwkrtedfarellaftflhdfe
vfeetpldlsgftdpeelaqflwgppdtapgalehhhhhh

    Sequence, based on observed residues (ATOM records):
    >6iy9B (B:)
eslllldridsddsyaslrndqefweplarraleelglpvppvlrvpgestnpvlvgepg
pviklfgehwcgpeslaseseayavladapvpvprllgrgelrpgtgawpwpylvmsrmt
gttwrsamdgttdrnallalarelgrvlgrlhrvpltgntvltphsevfpellrerraat
vedhrgwgylsprlldrledwlpdvdtllagreprfvhgdlhgtnifvdlaatevtgivd
ftdvyagdsryslvqlhlnafrgdreilaalldgaqwkrtedfarellaftflhdfevfe
etpldlsgftdpeelaqflwgppd