PDB entry 6ixa

View 6ixa on RCSB PDB site
Description: cryo-em structures of alphacoronavirus spike glycoprotein
Deposited on 2018-12-09, released 2020-06-17
Made obsolete by 7cyc on 2020-12-23

The last revision was dated 2020-12-23, with a file datestamp of 2020-12-18.
Experiment type: EM
Resolution: 3.21 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Spike glycoprotein
    Species: Human coronavirus 229E [TaxId:11137]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15423
      • variant (641)
      • variant (680)
      • variant (764)
      • variant (774)
      • variant (870)
      • variant (936)
      • variant (970)
      • variant (1004)
  • Chain 'B':
    Compound: Spike glycoprotein
    Species: Human coronavirus 229E [TaxId:11137]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15423
      • variant (641)
      • variant (680)
      • variant (764)
      • variant (774)
      • variant (870)
      • variant (936)
      • variant (970)
      • variant (1004)
  • Chain 'C':
    Compound: Spike glycoprotein
    Species: Human coronavirus 229E [TaxId:11137]
    Gene: S, 2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15423
      • variant (641)
      • variant (680)
      • variant (764)
      • variant (774)
      • variant (870)
      • variant (936)
      • variant (970)
      • variant (1004)
  • Heterogens: BMA, MAN, NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ixaA (A:)
    mfvllvayallhiagcqttnglntsysvcngcvgysenvfavesggyipsdfafnnwfll
    tntssvvdgvvrsfqplllnclwsvsglrfttgfvyfngtgrgdckgfssdvlsdviryn
    lnfeenlrrgtilfktsygvvvfyctnntlvsgdahipfgtvlgnfycfvnttignetts
    afvgalpktvrefvisrtghfyingyryftlgnveavnfnvttaettdfctvalasyadv
    lvnvsqtsianiiycnsvinrlrcdqlsfdvpdgfystspiqsvelpvsivslpvyhkht
    fivlyvdfkpqsgggkcfncypagvnitlanfnetkgplcvdtshfttkyvavyanvgrw
    sasintgncpfsfgkvnnfvkfgsvcfslkdipggcampivanwayskyytigslyvsws
    dgdgitgvpqpvegvssfmnvtldkctkyniydvsgvgvirvsndtflngitytstsgnl
    lgfkdvtkgtiysitpcnppdqlvvyqqavvgamlsenftsygfsnvvelpkffyasngt
    ynctdavltyssfgvcadgsiiavqprnvsydsvsaivtanlsipsnwttsvqveylqit
    stpivvdcstyvcngnvrcvellkqytsacktiedalrnsamlesadvsemltfdkkaft
    lanvssfgdynlssvipslprsgsrvagrsaiedilfsklvtsglgtvdadykkctkgls
    iadlacaqyyngimvlpgvadaermamytgsliggialggltsaasipfslaiqsrlnyv
    alqtdvlqenqkilaasfnkamtnivdaftgvndaitqtsqalqtvatalnkiqdvvnqq
    gnslnhltsqlrqnfqaisssiqaiydrldiiqadqqvdrlitgrlaalnvfvshtltky
    tevrasrqlaqqkvnecvksqskrygfcgngthifslvnaapeglvflhtvllptqykdv
    eawsglcvdgrngyvlrqpnlalykegnyyritsrimfepriptiadfvqiencnvtfvn
    isrselqtivpeyidvnktlqelsyklpnytvpdlvveqynqtilnltseistlenksae
    lnytvqklqtlidninstlvdlkwlnrvetyikwpw
    

    Sequence, based on observed residues (ATOM records):
    >6ixaA (A:)
    ipsdfafnnwflltntssvvdgvvrsfqplllnclwsvsglrfttgfvyfngtgrgdckg
    fssdvlsdvirynlnfeenlrrgtilfktsygvvvfyctnntlvsgdanfycfvnttign
    ettsafvgalpktvrefvisrtghfyingyryftlgnveavnfnvttaettdfctvalas
    yadvlvnvsqtsianiiycnsvinrlrcdqlsfdvpdgfystspiqsvelpvsivslpvy
    hkhtfivlyvdfkpqsgggkcfncypagvnitlanfnetkgplcvdtshfttkyvavyan
    vgrwsasintgncpfsfgkvnnfvkfgsvcfslkdipggcampivanwayskyytigsly
    vswsdgdgitgvpqpvegvssfmnvtldkctkyniydvsgvgvirvsndtflngitytst
    sgnllgfkdvtkgtiysitpcnppdqlvvyqqavvgamlsenftsygfsnvvelpkffya
    sngtynctdavltyssfgvcadgsiiavqprnvsydsvsaivtanlsipsnwttsvqvey
    lqitstpivvdcstyvcngnvrcvellkqytsacktiedalrnsamlesadvsemltfdk
    kaftlanvssfgdynlssvipslprsgsrvagrsaiedilfskladykkctkglsiadla
    caqyyngimvlpgvadaermamytgsliggialggltsaasipfslaiqsrlnyvalqtd
    vlqenqkilaasfnkamtnivdaftsqalqtvatalnkiqdvvnqqgnslnhltsqlrqn
    fqaisssiqaiydrldiiqadqqvdrlitgrlaalnvfvshtltkytevrasrqlaqqkv
    necvksqskrygfcgngthifslvnaapeglvflhtvllptqykdveawsglcvdgrngy
    vlrqpnlalykegnyyritsrimfepriptiadfvqiencnvtfvnisrselqtivpey
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ixaB (B:)
    mfvllvayallhiagcqttnglntsysvcngcvgysenvfavesggyipsdfafnnwfll
    tntssvvdgvvrsfqplllnclwsvsglrfttgfvyfngtgrgdckgfssdvlsdviryn
    lnfeenlrrgtilfktsygvvvfyctnntlvsgdahipfgtvlgnfycfvnttignetts
    afvgalpktvrefvisrtghfyingyryftlgnveavnfnvttaettdfctvalasyadv
    lvnvsqtsianiiycnsvinrlrcdqlsfdvpdgfystspiqsvelpvsivslpvyhkht
    fivlyvdfkpqsgggkcfncypagvnitlanfnetkgplcvdtshfttkyvavyanvgrw
    sasintgncpfsfgkvnnfvkfgsvcfslkdipggcampivanwayskyytigslyvsws
    dgdgitgvpqpvegvssfmnvtldkctkyniydvsgvgvirvsndtflngitytstsgnl
    lgfkdvtkgtiysitpcnppdqlvvyqqavvgamlsenftsygfsnvvelpkffyasngt
    ynctdavltyssfgvcadgsiiavqprnvsydsvsaivtanlsipsnwttsvqveylqit
    stpivvdcstyvcngnvrcvellkqytsacktiedalrnsamlesadvsemltfdkkaft
    lanvssfgdynlssvipslprsgsrvagrsaiedilfsklvtsglgtvdadykkctkgls
    iadlacaqyyngimvlpgvadaermamytgsliggialggltsaasipfslaiqsrlnyv
    alqtdvlqenqkilaasfnkamtnivdaftgvndaitqtsqalqtvatalnkiqdvvnqq
    gnslnhltsqlrqnfqaisssiqaiydrldiiqadqqvdrlitgrlaalnvfvshtltky
    tevrasrqlaqqkvnecvksqskrygfcgngthifslvnaapeglvflhtvllptqykdv
    eawsglcvdgrngyvlrqpnlalykegnyyritsrimfepriptiadfvqiencnvtfvn
    isrselqtivpeyidvnktlqelsyklpnytvpdlvveqynqtilnltseistlenksae
    lnytvqklqtlidninstlvdlkwlnrvetyikwpw
    

    Sequence, based on observed residues (ATOM records):
    >6ixaB (B:)
    ipsdfafnnwflltntssvvdgvvrsfqplllnclwsvsglrfttgfvyfngtgrgdckg
    fssdvlsdvirynlnfeenlrrgtilfktsygvvvfyctnntlvsgdanfycfvnttign
    ettsafvgalpktvrefvisrtghfyingyryftlgnveavnfnvttaettdfctvalas
    yadvlvnvsqtsianiiycnsvinrlrcdqlsfdvpdgfystspiqsvelpvsivslpvy
    hkhtfivlyvdfkpqsgggkcfncypagvnitlanfnetkgplcvdtshfttkyvavyan
    vgrwsasintgncpfsfgkvnnfvkfgsvcfslkdipggcampivanwayskyytigsly
    vswsdgdgitgvpqpvegvssfmnvtldkctkyniydvsgvgvirvsndtflngitytst
    sgnllgfkdvtkgtiysitpcnppdqlvvyqqavvgamlsenftsygfsnvvelpkffya
    sngtynctdavltyssfgvcadgsiiavqprnvsydsvsaivtanlsipsnwttsvqvey
    lqitstpivvdcstyvcngnvrcvellkqytsacktiedalrnsamlesadvsemltfdk
    kaftlanvssfgdynlssvipslprsgsrvagrsaiedilfskladykkctkglsiadla
    caqyyngimvlpgvadaermamytgsliggialggltsaasipfslaiqsrlnyvalqtd
    vlqenqkilaasfnkamtnivdaftsqalqtvatalnkiqdvvnqqgnslnhltsqlrqn
    fqaisssiqaiydrldiiqadqqvdrlitgrlaalnvfvshtltkytevrasrqlaqqkv
    necvksqskrygfcgngthifslvnaapeglvflhtvllptqykdveawsglcvdgrngy
    vlrqpnlalykegnyyritsrimfepriptiadfvqiencnvtfvnisrselqtivpey
    

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6ixaC (C:)
    mfvllvayallhiagcqttnglntsysvcngcvgysenvfavesggyipsdfafnnwfll
    tntssvvdgvvrsfqplllnclwsvsglrfttgfvyfngtgrgdckgfssdvlsdviryn
    lnfeenlrrgtilfktsygvvvfyctnntlvsgdahipfgtvlgnfycfvnttignetts
    afvgalpktvrefvisrtghfyingyryftlgnveavnfnvttaettdfctvalasyadv
    lvnvsqtsianiiycnsvinrlrcdqlsfdvpdgfystspiqsvelpvsivslpvyhkht
    fivlyvdfkpqsgggkcfncypagvnitlanfnetkgplcvdtshfttkyvavyanvgrw
    sasintgncpfsfgkvnnfvkfgsvcfslkdipggcampivanwayskyytigslyvsws
    dgdgitgvpqpvegvssfmnvtldkctkyniydvsgvgvirvsndtflngitytstsgnl
    lgfkdvtkgtiysitpcnppdqlvvyqqavvgamlsenftsygfsnvvelpkffyasngt
    ynctdavltyssfgvcadgsiiavqprnvsydsvsaivtanlsipsnwttsvqveylqit
    stpivvdcstyvcngnvrcvellkqytsacktiedalrnsamlesadvsemltfdkkaft
    lanvssfgdynlssvipslprsgsrvagrsaiedilfsklvtsglgtvdadykkctkgls
    iadlacaqyyngimvlpgvadaermamytgsliggialggltsaasipfslaiqsrlnyv
    alqtdvlqenqkilaasfnkamtnivdaftgvndaitqtsqalqtvatalnkiqdvvnqq
    gnslnhltsqlrqnfqaisssiqaiydrldiiqadqqvdrlitgrlaalnvfvshtltky
    tevrasrqlaqqkvnecvksqskrygfcgngthifslvnaapeglvflhtvllptqykdv
    eawsglcvdgrngyvlrqpnlalykegnyyritsrimfepriptiadfvqiencnvtfvn
    isrselqtivpeyidvnktlqelsyklpnytvpdlvveqynqtilnltseistlenksae
    lnytvqklqtlidninstlvdlkwlnrvetyikwpw
    

    Sequence, based on observed residues (ATOM records):
    >6ixaC (C:)
    ipsdfafnnwflltntssvvdgvvrsfqplllnclwsvsglrfttgfvyfngtgrgdckg
    fssdvlsdvirynlnfeenlrrgtilfktsygvvvfyctnntlvsgdanfycfvnttign
    ettsafvgalpktvrefvisrtghfyingyryftlgnveavnfnvttaettdfctvalas
    yadvlvnvsqtsianiiycnsvinrlrcdqlsfdvpdgfystspiqsvelpvsivslpvy
    hkhtfivlyvdfkpqsgggkcfncypagvnitlanfnetkgplcvdtshfttkyvavyan
    vgrwsasintgncpfsfgkvnnfvkfgsvcfslkdipggcampivanwayskyytigsly
    vswsdgdgitgvpqpvegvssfmnvtldkctkyniydvsgvgvirvsndtflngitytst
    sgnllgfkdvtkgtiysitpcnppdqlvvyqqavvgamlsenftsygfsnvvelpkffya
    sngtynctdavltyssfgvcadgsiiavqprnvsydsvsaivtanlsipsnwttsvqvey
    lqitstpivvdcstyvcngnvrcvellkqytsacktiedalrnsamlesadvsemltfdk
    kaftlanvssfgdynlssvipslprsgsrvagrsaiedilfskladykkctkglsiadla
    caqyyngimvlpgvadaermamytgsliggialggltsaasipfslaiqsrlnyvalqtd
    vlqenqkilaasfnkamtnivdaftsqalqtvatalnkiqdvvnqqgnslnhltsqlrqn
    fqaisssiqaiydrldiiqadqqvdrlitgrlaalnvfvshtltkytevrasrqlaqqkv
    necvksqskrygfcgngthifslvnaapeglvflhtvllptqykdveawsglcvdgrngy
    vlrqpnlalykegnyyritsrimfepriptiadfvqiencnvtfvnisrselqtivpey