PDB entry 6ix2

View 6ix2 on RCSB PDB site
Description: Structure of the A214C/A250I mutant of an epoxide hydrolase from Aspergillus usamii E001 (AuEH2) at 1.48 Angstroms resolution
Class: hydrolase
Keywords: Alpha and beta proteins, alpha/beta-Hydrolases, Styrene Oxide, HYDROLASE
Deposited on 2018-12-09, released 2019-12-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-11, with a file datestamp of 2019-12-06.
Experiment type: XRAY
Resolution: 1.48 Å
R-factor: N/A
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Microsomal epoxide hyddrolase
    Species: Aspergillus usamii [TaxId:186680]
    Gene: EH2
    Database cross-references and differences (RAF-indexed):
    • Uniprot T2B4K5 (36-End)
      • expression tag (34-35)
      • engineered mutation (249)
      • engineered mutation (285)
    Domains in SCOPe 2.08: d6ix2a1, d6ix2a2
  • Chain 'B':
    Compound: Microsomal epoxide hyddrolase
    Species: Aspergillus usamii [TaxId:186680]
    Gene: EH2
    Database cross-references and differences (RAF-indexed):
    • Uniprot T2B4K5
      • engineered mutation (249)
      • engineered mutation (285)
    Domains in SCOPe 2.08: d6ix2b_
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ix2A (A:)
mgsshhhhhhssglvprgshmasmtggqqmgrgsefmalaysniplgatvipspfqvhis
deqieelqllvklsklapptyeglqqdrrygitnewlanakeawksfdwrpaesrinsfp
qftydiegltihfvalfsekkdaipivllhgwpgsfleflpvltsirdkyspetlpyhiv
vpslpgytfssgppldvnfngedtarvinkvmlnlgfedgyvaqggdigskigrilavdh
dackavhlnccymgkpssipdtaiteedkralaraqwfatfgsgyivehgtrpstignal
stspvallswigekfldwagetipletilesvtlywftetfprsiyhyrenfpppklrht
edprwyirkpfgfsyypmelvptprawvettgnlvfwqahekgghfaalerpqdylddlt
afceqvwagrk

    Sequence, based on observed residues (ATOM records): (download) 
    >6ix2A (A:)
efmalaysniplgatvipspfqvhisdeqieelqllvklsklapptyeglqqdrrygitn
ewlanakeawksfdwrpaesrinsfpqftydiegltihfvalfsekkdaipivllhgwpg
sfleflpvltsirdkyspetlpyhivvpslpgytfssgppldvnfngedtarvinkvmln
lgfedgyvaqggdigskigrilavdhdackavhlnccymgkpssipdaqwfatfgsgyiv
ehgtrpstignalstspvallswigekfldwagetipletilesvtlywftetfprsiyh
yrenfpppklrhtedprwyirkpfgfsyypmelvptprawvettgnlvfwqahekgghfa
alerpqdylddltafceqvwag

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6ix2B (B:)
mgsshhhhhhssglvprgshmasmtggqqmgrgsefmalaysniplgatvipspfqvhis
deqieelqllvklsklapptyeglqqdrrygitnewlanakeawksfdwrpaesrinsfp
qftydiegltihfvalfsekkdaipivllhgwpgsfleflpvltsirdkyspetlpyhiv
vpslpgytfssgppldvnfngedtarvinkvmlnlgfedgyvaqggdigskigrilavdh
dackavhlnccymgkpssipdtaiteedkralaraqwfatfgsgyivehgtrpstignal
stspvallswigekfldwagetipletilesvtlywftetfprsiyhyrenfpppklrht
edprwyirkpfgfsyypmelvptprawvettgnlvfwqahekgghfaalerpqdylddlt
afceqvwagrk

    Sequence, based on observed residues (ATOM records): (download) 
    >6ix2B (B:)
laysniplgatvipspfqvhisdeqieelqllvklsklapptyeglqqdrrygitnewla
nakeawksfdwrpaesrinsfpqftydiegltihfvalfsekkdaipivllhgwpgsfle
flpvltsirdkyspetlpyhivvpslpgytfssgppldvnfngedtarvinkvmlnlgfe
dgyvaqggdigskigrilavdhdackavhlnccymgkpteedkralaraqwfatfgsgyi
vehgtrpstignalstspvallswigekfldwagetipletilesvtlywftetfprsiy
hyrenfpppklrhtedprwyirkpfgfsyypmelvptprawvettgnlvfwqahekgghf
aalerpqdylddltafceqvwag