PDB entry 6ivk

View 6ivk on RCSB PDB site
Description: Crystal structure of a membrane protein G175A
Class: membrane protein
Keywords: membrane protein
Deposited on 2018-12-04, released 2019-11-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-11-06, with a file datestamp of 2019-11-01.
Experiment type: XRAY
Resolution: 2.65 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ibestrophin
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: yneE, AGG09_26735, B1727_16705, B4U21_14105, B4U25_16730, B4U27_02655, B4U30_16350, B4U35_20780, BB785_13310, BN49_2925, C3483_12335, C7V41_19985, CPT10_17935, CWN54_25435, CWQ24_13475, DM060_34770, DM071_16710, DM078_14870, DM083_28480, DMR37_19630, DXF97_13395, NCTC11679_02573, NCTC13465_00112, NCTC5052_01714, NCTC8849_03195, NCTC9637_03467, NCTC9645_05950, NCTC9661_03571, SAMEA104305404_11875, SAMEA23986918_00256, SAMEA24002668_02597, SAMEA24012418_00268, SAMEA3649709_04169, SAMEA3673019_02937, SAMEA3727643_02313, SAMEA4394730_00268
    Database cross-references and differences (RAF-indexed):
    • Uniprot W9BH30
      • engineered mutation (177)
    Domains in SCOPe 2.08: d6ivka_
  • Chain 'B':
    Compound: Ibestrophin
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: yneE, AGG09_26735, B1727_16705, B4U21_14105, B4U25_16730, B4U27_02655, B4U30_16350, B4U35_20780, BB785_13310, BN49_2925, C3483_12335, C7V41_19985, CPT10_17935, CWN54_25435, CWQ24_13475, DM060_34770, DM071_16710, DM078_14870, DM083_28480, DMR37_19630, DXF97_13395, NCTC11679_02573, NCTC13465_00112, NCTC5052_01714, NCTC8849_03195, NCTC9637_03467, NCTC9645_05950, NCTC9661_03571, SAMEA104305404_11875, SAMEA23986918_00256, SAMEA24002668_02597, SAMEA24012418_00268, SAMEA3649709_04169, SAMEA3673019_02937, SAMEA3727643_02313, SAMEA4394730_00268
    Database cross-references and differences (RAF-indexed):
    • Uniprot W9BH30
      • engineered mutation (177)
    Domains in SCOPe 2.08: d6ivkb_
  • Chain 'C':
    Compound: Ibestrophin
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: yneE, AGG09_26735, B1727_16705, B4U21_14105, B4U25_16730, B4U27_02655, B4U30_16350, B4U35_20780, BB785_13310, BN49_2925, C3483_12335, C7V41_19985, CPT10_17935, CWN54_25435, CWQ24_13475, DM060_34770, DM071_16710, DM078_14870, DM083_28480, DMR37_19630, DXF97_13395, NCTC11679_02573, NCTC13465_00112, NCTC5052_01714, NCTC8849_03195, NCTC9637_03467, NCTC9645_05950, NCTC9661_03571, SAMEA104305404_11875, SAMEA23986918_00256, SAMEA24002668_02597, SAMEA24012418_00268, SAMEA3649709_04169, SAMEA3673019_02937, SAMEA3727643_02313, SAMEA4394730_00268
    Database cross-references and differences (RAF-indexed):
    • Uniprot W9BH30
      • engineered mutation (177)
    Domains in SCOPe 2.08: d6ivkc_
  • Chain 'D':
    Compound: Ibestrophin
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: yneE, AGG09_26735, B1727_16705, B4U21_14105, B4U25_16730, B4U27_02655, B4U30_16350, B4U35_20780, BB785_13310, BN49_2925, C3483_12335, C7V41_19985, CPT10_17935, CWN54_25435, CWQ24_13475, DM060_34770, DM071_16710, DM078_14870, DM083_28480, DMR37_19630, DXF97_13395, NCTC11679_02573, NCTC13465_00112, NCTC5052_01714, NCTC8849_03195, NCTC9637_03467, NCTC9645_05950, NCTC9661_03571, SAMEA104305404_11875, SAMEA23986918_00256, SAMEA24002668_02597, SAMEA24012418_00268, SAMEA3649709_04169, SAMEA3673019_02937, SAMEA3727643_02313, SAMEA4394730_00268
    Database cross-references and differences (RAF-indexed):
    • Uniprot W9BH30
      • engineered mutation (177)
    Domains in SCOPe 2.08: d6ivkd_
  • Chain 'E':
    Compound: Ibestrophin
    Species: Klebsiella pneumoniae [TaxId:573]
    Gene: yneE, AGG09_26735, B1727_16705, B4U21_14105, B4U25_16730, B4U27_02655, B4U30_16350, B4U35_20780, BB785_13310, BN49_2925, C3483_12335, C7V41_19985, CPT10_17935, CWN54_25435, CWQ24_13475, DM060_34770, DM071_16710, DM078_14870, DM083_28480, DMR37_19630, DXF97_13395, NCTC11679_02573, NCTC13465_00112, NCTC5052_01714, NCTC8849_03195, NCTC9637_03467, NCTC9645_05950, NCTC9661_03571, SAMEA104305404_11875, SAMEA23986918_00256, SAMEA24002668_02597, SAMEA24012418_00268, SAMEA3649709_04169, SAMEA3673019_02937, SAMEA3727643_02313, SAMEA4394730_00268
    Database cross-references and differences (RAF-indexed):
    • Uniprot W9BH30 (Start-296)
      • engineered mutation (177)
    Domains in SCOPe 2.08: d6ivke_
  • Heterogens: ZN, ACY, EDO, CL, PGE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ivkA (A:)
snamiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapf
sllgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsy
lvafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreaakl
sdityglmdnkldelahvlggcerlattpvpfaytlilqrtvylfctllpfalvgdlhym
tpfvsvfisytflswdslaeeledpfgtaandlplnamcntiernlldmtgqhplpe

    Sequence, based on observed residues (ATOM records): (download) 
    >6ivkA (A:)
skiifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsasysrfve
arnlwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdptadlrrl
lpeervteilassmptnrilllagneigqlreaaklsdityglmdnkldelahvlggcer
lattpvpfaytlilqrtvylfctllpfalvgdlhymtpfvsvfisytflswdslaeeled
pfgtaandlplnamcntiernlldmtgq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6ivkB (B:)
snamiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapf
sllgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsy
lvafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreaakl
sdityglmdnkldelahvlggcerlattpvpfaytlilqrtvylfctllpfalvgdlhym
tpfvsvfisytflswdslaeeledpfgtaandlplnamcntiernlldmtgqhplpe

    Sequence, based on observed residues (ATOM records): (download) 
    >6ivkB (B:)
skiifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsasysrfve
arnlwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdptadlrrl
lpeervteilassmptnrilllagneigqlreaaklsdityglmdnkldelahvlggcer
lattpvpfaytlilqrtvylfctllpfalvgdlhymtpfvsvfisytflswdslaeeled
pfgtaandlplnamcntiernlldmtgqhplp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6ivkC (C:)
snamiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapf
sllgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsy
lvafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreaakl
sdityglmdnkldelahvlggcerlattpvpfaytlilqrtvylfctllpfalvgdlhym
tpfvsvfisytflswdslaeeledpfgtaandlplnamcntiernlldmtgqhplpe

    Sequence, based on observed residues (ATOM records): (download) 
    >6ivkC (C:)
skiifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsasysrfve
arnlwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdptadlrrl
lpeervteilassmptnrilllagneigqlreaaklsdityglmdnkldelahvlggcer
lattpvpfaytlilqrtvylfctllpfalvgdlhymtpfvsvfisytflswdslaeeled
pfgtaandlplnamcntiernlldmtgqhp

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6ivkD (D:)
snamiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapf
sllgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsy
lvafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreaakl
sdityglmdnkldelahvlggcerlattpvpfaytlilqrtvylfctllpfalvgdlhym
tpfvsvfisytflswdslaeeledpfgtaandlplnamcntiernlldmtgqhplpe

    Sequence, based on observed residues (ATOM records): (download) 
    >6ivkD (D:)
skiifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsasysrfve
arnlwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdptadlrrl
lpeervteilassmptnrilllagneigqlreaaklsdityglmdnkldelahvlggcer
lattpvpfaytlilqrtvylfctllpfalvgdlhymtpfvsvfisytflswdslaeeled
pfgtaandlplnamcntiernlldmtgq

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6ivkE (E:)
snamiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapf
sllgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsy
lvafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreaakl
sdityglmdnkldelahvlggcerlattpvpfaytlilqrtvylfctllpfalvgdlhym
tpfvsvfisytflswdslaeeledpfgtaandlplnamcntiernlldmtgqhplpe

    Sequence, based on observed residues (ATOM records): (download) 
    >6ivkE (E:)
iifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsasysrfvear
nlwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdptadlrrllp
eervteilassmptnrilllagneigqlreaaklsdityglmdnkldelahvlggcerla
ttpvpfaytlilqrtvylfctllpfalvgdlhymtpfvsvfisytflswdslaeeledpf
gtaandlplnamcntiernlldmtgqhplpe