PDB entry 6iv8

View 6iv8 on RCSB PDB site
Description: the selenomethionine(semet)-derived cas13d binary complex
Deposited on 2018-12-02, released 2019-06-19
The last revision was dated 2019-06-26, with a file datestamp of 2019-06-21.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: The selenomethionine (SeMet)-labeled Cas13d
    Species: uncultured Ruminococcus sp [TaxId:165186]
    Gene: SAMEA3545300_02264
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A1C5SD84 (Start-921)
      • engineered mutation (287)
      • engineered mutation (822)
  • Chain 'B':
    Compound: RNA (51-mer)
    Species: uncultured Ruminococcus sp. [TaxId:165186]
  • Chain 'C':
    Compound: The selenomethionine (SeMet)-labeled Cas13d
    Species: uncultured Ruminococcus sp [TaxId:165186]
    Gene: SAMEA3545300_02264
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A1C5SD84 (Start-921)
      • engineered mutation (287)
      • engineered mutation (822)
  • Chain 'D':
    Compound: RNA (53-mer)
    Species: uncultured Ruminococcus sp. [TaxId:165186]
  • Heterogens: MG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6iv8A (A:)
makknkmkprelreaqkkarqlkaaeinnnaapaiaampaaeviapvaekkkssvkaagm
ksilvsenkmyitsfgkgnsavleyevdnndynktqlsskdnsnielgdvnevnitfssk
hgfgsgveintsnpthrsgesspvrgdmlglkselekrffgktfddnihiqliynildie
kilavyvtnivyalnnmlgikdsesyddfmgylsarntyevfthpdksnlsdkvkgnikk
slskfndllktkrlgyfgleepktkdtraseaykkrvyhmlaivgqiaqcvfhdksgakr
fdlysfinnidpeyrdtldylveerlksinkdfiegnkvnisllidmmkgyeaddiirly
ydfivlksqknlgfsikklrekmleeygfrfkdkqydsvrskmyklmdfllfcnyyrndv
aagealvrklrfsmtddekegiyadeaaklwgkfrndfeniadhmngdvikelgkadmdf
dekildsekknasdllyfskmiymltyfldgkeindllttliskfdnikeflkimkssav
dveceltagyklfndsqritnelfivkniasmrkpaasakltmfrdaltilgiddnitdd
riseilklkekgkgihglrnfitnnviessrfvylikyanaqkirevaknekvvmfvlgg
ipdtqieryykscvefpdmnssleakrselarmiknisfddfknvkqqakgrenvakera
kaviglyltvmyllvknlvnvnaryviaihclerdfglykeiipelasknlkndyrilsq
tlcelcddrnessnlflkknkrlrkcvevdinnadssmtrkyanciahltvvrelkeyig
dirtvdsyfsiyhyvmqrcitkrgddtkqeekikyeddllknhgytkdfvkalnspfgyn
iprfknlsieqlfdrneylteklehhhhhh

    Sequence, based on observed residues (ATOM records):
    >6iv8A (A:)
ekkkssvkaagmksilvsenkmyitsfgkgnsavleyevdnndynktqlsskdnsnielg
dvnevnitfsskhgfgsgveintsnpthrsgesspvrgdmlglkselekrffgktfddni
hiqliynildiekilavyvtnivyalnnmlgikdsesyddfmgylsarntyevfthpdks
nlsdkvkgnikkslskfndllktkrlgyfgleepktkdtraseaykkrvyhmlaivgqia
qcvfhdksgakrfdlysfinnidpeyrdtldylveerlksinkdfiegnkvnisllidmm
kgyeaddiirlyydfivlksqknlgfsikklrekmleeygfrfkdkqydsvrskmyklmd
fllfcnyyrndvaagealvrklrfsmtddekegiyadeaaklwgkfrndfeniadhmngd
vikelgkadmdfdekildsekknasdllyfskmiymltyfldgkeindllttliskfdni
keflkimkssavdveceltagyklfndsqritnelfivkniasmrkpaasakltmfrdal
tilgiddnitddriseilklkekgkgihglrnfitnnviessrfvylikyanaqkireva
knekvvmfvlggipdtqieryykscvefpdmnssleakrselarmiknisfddfknvkqq
akgrenvakerakaviglyltvmyllvknlvnvnaryviaihclerdfglykeiipelas
knlkndyrilsqtlcelcddrnessnlflkknkrlrkcvevdinnadssmtrkyanciah
ltvvrelkeyigdirtvdsyfsiyhyvmqrcitkrgeekikyeddllknhgytkdfvkal
nspfgyniprfknlsieqlfdrneyltek

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6iv8C (C:)
makknkmkprelreaqkkarqlkaaeinnnaapaiaampaaeviapvaekkkssvkaagm
ksilvsenkmyitsfgkgnsavleyevdnndynktqlsskdnsnielgdvnevnitfssk
hgfgsgveintsnpthrsgesspvrgdmlglkselekrffgktfddnihiqliynildie
kilavyvtnivyalnnmlgikdsesyddfmgylsarntyevfthpdksnlsdkvkgnikk
slskfndllktkrlgyfgleepktkdtraseaykkrvyhmlaivgqiaqcvfhdksgakr
fdlysfinnidpeyrdtldylveerlksinkdfiegnkvnisllidmmkgyeaddiirly
ydfivlksqknlgfsikklrekmleeygfrfkdkqydsvrskmyklmdfllfcnyyrndv
aagealvrklrfsmtddekegiyadeaaklwgkfrndfeniadhmngdvikelgkadmdf
dekildsekknasdllyfskmiymltyfldgkeindllttliskfdnikeflkimkssav
dveceltagyklfndsqritnelfivkniasmrkpaasakltmfrdaltilgiddnitdd
riseilklkekgkgihglrnfitnnviessrfvylikyanaqkirevaknekvvmfvlgg
ipdtqieryykscvefpdmnssleakrselarmiknisfddfknvkqqakgrenvakera
kaviglyltvmyllvknlvnvnaryviaihclerdfglykeiipelasknlkndyrilsq
tlcelcddrnessnlflkknkrlrkcvevdinnadssmtrkyanciahltvvrelkeyig
dirtvdsyfsiyhyvmqrcitkrgddtkqeekikyeddllknhgytkdfvkalnspfgyn
iprfknlsieqlfdrneylteklehhhhhh

    Sequence, based on observed residues (ATOM records):
    >6iv8C (C:)
kkkssvkaagmksilvsenkmyitsfgkgnsavleyevdnndynktqlsskdnsnielgd
vnevnitfsskhgfgsgveintsnpthrsgesspvrgdmlglkselekrffgktfddnih
iqliynildiekilavyvtnivyalnnmlgiksyddfmgylsarntyevfthpdksnlsd
kvkgnikkslskfndllktkrlgyfgleepktkdtraseaykkrvyhmlaivgqiaqcvf
hdksgakrfdlysfinnidpeyrdtldylveerlksinkdfiegnkvnisllidmmkgye
addiirlyydfivlksqknlgfsikklrekmleeygfrfkdkqydsvrskmyklmdfllf
cnyyrndvaagealvrklrfsmtddekegiyadeaaklwgkfrndfeniadhmngdvike
lgkadmdfdekildsekknasdllyfskmiymltyfldgkeindllttliskfdnikefl
kimkssavdveceltagyklfndsqritnelfivkniasmrkpaasakltmfrdaltilg
iddnitddriseilklkekgkgihglrnfitnnviessrfvylikyanaqkirevaknek
vvmfvlggipdtqieryykscvefpdmnssleakrselarmiknisfddfknvkqqakgr
envakerakaviglyltvmyllvknlvnvnaryviaihclerdfglykeiipelasknlk
ndyrilsqtlcelcddrnessnlflkknkrlrkcvevdinnadssmtrkyanciahltvv
relkeyigdirtvdsyfsiyhyvmqrcitkrkikyeddllknhgytkdfvkalnspfgyn
iprfknlsieqlfdrneyltek

  • Chain 'D':
    No sequence available.