PDB entry 6iv3

View 6iv3 on RCSB PDB site
Description: Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae with a mutation W252A
Class: membrane protein
Keywords: Bestrophin-1, homolog, mutation, klebsiella pneumoniae, MEMBRANE PROTEIN
Deposited on 2018-12-02, released 2019-11-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-11-13, with a file datestamp of 2019-11-08.
Experiment type: XRAY
Resolution: 2.52 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bestrophin homolog
    Species: Klebsiella pneumoniae IS53 [TaxId:1432554]
    Database cross-references and differences (RAF-indexed):
    • Uniprot W1ELP7
      • engineered mutation (253)
    Domains in SCOPe 2.08: d6iv3a_
  • Chain 'B':
    Compound: Bestrophin homolog
    Species: Klebsiella pneumoniae IS53 [TaxId:1432554]
    Database cross-references and differences (RAF-indexed):
    • Uniprot W1ELP7
      • engineered mutation (253)
    Domains in SCOPe 2.08: d6iv3b_
  • Chain 'C':
    Compound: Bestrophin homolog
    Species: Klebsiella pneumoniae IS53 [TaxId:1432554]
    Database cross-references and differences (RAF-indexed):
    • Uniprot W1ELP7
      • engineered mutation (253)
    Domains in SCOPe 2.08: d6iv3c_
  • Chain 'D':
    Compound: Bestrophin homolog
    Species: Klebsiella pneumoniae IS53 [TaxId:1432554]
    Database cross-references and differences (RAF-indexed):
    • Uniprot W1ELP7
      • engineered mutation (253)
    Domains in SCOPe 2.08: d6iv3d_
  • Chain 'E':
    Compound: Bestrophin homolog
    Species: Klebsiella pneumoniae IS53 [TaxId:1432554]
    Database cross-references and differences (RAF-indexed):
    • Uniprot W1ELP7
      • engineered mutation (253)
    Domains in SCOPe 2.08: d6iv3e_
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6iv3A (A:)
namiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapfs
llgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsyl
vafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreagkls
dityglmdnkldelahvlggcerlattpvpfaytlilqrtvylfctllpfalvgdlhymt
pfvsvfisytflsadslaeeledpfgtaandlplnamcntiernlldmtgqhplpe

    Sequence, based on observed residues (ATOM records): (download) 
    >6iv3A (A:)
whgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsas
ysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdpt
adlrrllpeervteilassmptnrilllagneigqlreagklsdityglmdnkldelahv
lggcerlattpvpfaytlilqrtvylfctllpfalvgdlhymtpfvsvfisytflsadsl
aeeledpfgtaandlplnamcntiernlldmtgq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6iv3B (B:)
namiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapfs
llgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsyl
vafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreagkls
dityglmdnkldelahvlggcerlattpvpfaytlilqrtvylfctllpfalvgdlhymt
pfvsvfisytflsadslaeeledpfgtaandlplnamcntiernlldmtgqhplpe

    Sequence, based on observed residues (ATOM records): (download) 
    >6iv3B (B:)
lskiifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsasysrfv
earnlwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdptadlrr
llpeervteilassmptnrilllagneigqlreagklsdityglmdnkldelahvlggce
rlattpvpfaytlilqrtvylfctllpfalvgdlhymtpfvsvfisytflsadslaeele
dpfgtaandlplnamcntiernlldmtgqhpl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6iv3C (C:)
namiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapfs
llgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsyl
vafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreagkls
dityglmdnkldelahvlggcerlattpvpfaytlilqrtvylfctllpfalvgdlhymt
pfvsvfisytflsadslaeeledpfgtaandlplnamcntiernlldmtgqhplpe

    Sequence, based on observed residues (ATOM records): (download) 
    >6iv3C (C:)
vlskiifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsasysrf
vearnlwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdptadlr
rllpeervteilassmptnrilllagneigqlreagklsdityglmdnkldelahvlggc
erlattpvpfaytlilqrtvylfctllpfalvgdlhymtpfvsvfisytflsadslaeel
edpfgtaandlplnamcntiernlldmtgqh

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6iv3D (D:)
namiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapfs
llgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsyl
vafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreagkls
dityglmdnkldelahvlggcerlattpvpfaytlilqrtvylfctllpfalvgdlhymt
pfvsvfisytflsadslaeeledpfgtaandlplnamcntiernlldmtgqhplpe

    Sequence, based on observed residues (ATOM records): (download) 
    >6iv3D (D:)
skiifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsasysrfve
arnlwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdptadlrrl
lpeervteilassmptnrilllagneigqlreagklsdityglmdnkldelahvlggcer
lattpvpfaytlilqrtvylfctllpfalvgdlhymtpfvsvfisytflsadslaeeled
pfgtaandlplnamcntiernlldmtgq

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6iv3E (E:)
namiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapfs
llgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsyl
vafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreagkls
dityglmdnkldelahvlggcerlattpvpfaytlilqrtvylfctllpfalvgdlhymt
pfvsvfisytflsadslaeeledpfgtaandlplnamcntiernlldmtgqhplpe

    Sequence, based on observed residues (ATOM records): (download) 
    >6iv3E (E:)
iifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsasysrfvear
nlwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdptadlrrllp
eervteilassmptnrilllagneigqlreagklsdityglmdnkldelahvlggcerla
ttpvpfaytlilqrtvylfctllpfalvgdlhymtpfvsvfisytflsadslaeeledpf
gtaandlplnamcntiernlldmtgqhplp