PDB entry 6iv2

View 6iv2 on RCSB PDB site
Description: Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae with a mutation Y211A
Class: membrane protein
Keywords: Bestrophin-1, homolog, mutation, klebsiella pneumoniae, MEMBRANE PROTEIN
Deposited on 2018-12-02, released 2019-11-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-11-13, with a file datestamp of 2019-11-08.
Experiment type: XRAY
Resolution: 2.62 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bestrophin homolog
    Species: Klebsiella pneumoniae IS53 [TaxId:1432554]
    Database cross-references and differences (RAF-indexed):
    • Uniprot W1ELP7
      • engineered mutation (212)
    Domains in SCOPe 2.08: d6iv2a_
  • Chain 'B':
    Compound: Bestrophin homolog
    Species: Klebsiella pneumoniae IS53 [TaxId:1432554]
    Database cross-references and differences (RAF-indexed):
    • Uniprot W1ELP7
      • engineered mutation (212)
    Domains in SCOPe 2.08: d6iv2b_
  • Chain 'C':
    Compound: Bestrophin homolog
    Species: Klebsiella pneumoniae IS53 [TaxId:1432554]
    Database cross-references and differences (RAF-indexed):
    • Uniprot W1ELP7
      • engineered mutation (212)
    Domains in SCOPe 2.08: d6iv2c_
  • Chain 'D':
    Compound: Bestrophin homolog
    Species: Klebsiella pneumoniae IS53 [TaxId:1432554]
    Database cross-references and differences (RAF-indexed):
    • Uniprot W1ELP7
      • engineered mutation (212)
    Domains in SCOPe 2.08: d6iv2d_
  • Chain 'E':
    Compound: Bestrophin homolog
    Species: Klebsiella pneumoniae IS53 [TaxId:1432554]
    Database cross-references and differences (RAF-indexed):
    • Uniprot W1ELP7
      • engineered mutation (212)
    Domains in SCOPe 2.08: d6iv2e_
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6iv2A (A:)
namiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapfs
llgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsyl
vafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreagkls
dityglmdnkldelahvlggcerlattpvpfaatlilqrtvylfctllpfalvgdlhymt
pfvsvfisytflswdslaeeledpfgtaandlplnamcntiernlldmtgqhplpe

    Sequence, based on observed residues (ATOM records): (download) 
    >6iv2A (A:)
skiifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsasysrfve
arnlwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdptadlrrl
lpeervteilassmptnrilllagneigqlreagklsdityglmdnkldelahvlggcer
lattppfaatlilqrtvylfctllpfalvgdlhymtpfvsvfisytflswdslaeeledp
fgtaandlplnamcntiernlldmtgq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6iv2B (B:)
namiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapfs
llgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsyl
vafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreagkls
dityglmdnkldelahvlggcerlattpvpfaatlilqrtvylfctllpfalvgdlhymt
pfvsvfisytflswdslaeeledpfgtaandlplnamcntiernlldmtgqhplpe

    Sequence, based on observed residues (ATOM records): (download) 
    >6iv2B (B:)
skiifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsasysrfve
arnlwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdptadlrrl
lpeervteilassmptnrilllagneigqlreagklsdityglmdnkldelahvlggcer
lattpvpfaatlilqrtvylfctllpfalvgdlhymtpfvsvfisytflswdslaeeled
pfgtaandlplnamcntiernlldmtg

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6iv2C (C:)
namiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapfs
llgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsyl
vafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreagkls
dityglmdnkldelahvlggcerlattpvpfaatlilqrtvylfctllpfalvgdlhymt
pfvsvfisytflswdslaeeledpfgtaandlplnamcntiernlldmtgqhplpe

    Sequence, based on observed residues (ATOM records): (download) 
    >6iv2C (C:)
iifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsasysrfvear
nlwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdptadlrrllp
eervteilassmptnrilllagneigqlreagklsdityglmdnkldelahvlggcerla
ttfaatlilqrtvylfctllpfalvgdlhymtpfvsvfisytflswdslaeeledpfgta
andlplnamcntiernlldmtg

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6iv2D (D:)
namiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapfs
llgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsyl
vafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreagkls
dityglmdnkldelahvlggcerlattpvpfaatlilqrtvylfctllpfalvgdlhymt
pfvsvfisytflswdslaeeledpfgtaandlplnamcntiernlldmtgqhplpe

    Sequence, based on observed residues (ATOM records): (download) 
    >6iv2D (D:)
skiifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsasysrfve
arnlwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdptadlrrl
lpeervteilassmptnrilllagneigqlreagklsdityglmdnkldelahvlggcer
lattpvpfaatlilqrtvylfctllpfalvgdlhymtpfvsvfisytflswdslaeeled
pfgtaandlplnamcntiernlldmtgq

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6iv2E (E:)
namiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapfs
llgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsyl
vafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreagkls
dityglmdnkldelahvlggcerlattpvpfaatlilqrtvylfctllpfalvgdlhymt
pfvsvfisytflswdslaeeledpfgtaandlplnamcntiernlldmtgqhplpe

    Sequence, based on observed residues (ATOM records): (download) 
    >6iv2E (E:)
ifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsasysrfvearn
lwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdptadlrrllpe
ervteilassmptnrilllagneigqlreagklsdityglmdnkldelahvlggcerlat
tpvpfaatlilqrtvylfctllpfalvgdlhymtpfvsvfisytflswdslaeeledpfg
taandlplnamcntiernlldmtgq