PDB entry 6iv1

View 6iv1 on RCSB PDB site
Description: Crystal structure of a bacterial Bestrophin homolog from Klebsiella pneumoniae with a mutation I180T
Class: membrane protein
Keywords: Bestrophin-1, homolog, mutation, klebsiella pneumoniae, MEMBRANE PROTEIN
Deposited on 2018-12-02, released 2019-11-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-11-13, with a file datestamp of 2019-11-08.
Experiment type: XRAY
Resolution: 3.18 Å
R-factor: N/A
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bestrophin homolog
    Species: Klebsiella pneumoniae IS53 [TaxId:1432554]
    Database cross-references and differences (RAF-indexed):
    • Uniprot W1ELP7
      • engineered mutation (181)
    Domains in SCOPe 2.08: d6iv1a_
  • Chain 'B':
    Compound: Bestrophin homolog
    Species: Klebsiella pneumoniae IS53 [TaxId:1432554]
    Database cross-references and differences (RAF-indexed):
    • Uniprot W1ELP7
      • engineered mutation (181)
    Domains in SCOPe 2.08: d6iv1b_
  • Chain 'C':
    Compound: Bestrophin homolog
    Species: Klebsiella pneumoniae IS53 [TaxId:1432554]
    Database cross-references and differences (RAF-indexed):
    • Uniprot W1ELP7
      • engineered mutation (181)
    Domains in SCOPe 2.08: d6iv1c_
  • Chain 'D':
    Compound: Bestrophin homolog
    Species: Klebsiella pneumoniae IS53 [TaxId:1432554]
    Database cross-references and differences (RAF-indexed):
    • Uniprot W1ELP7
      • engineered mutation (181)
    Domains in SCOPe 2.08: d6iv1d_
  • Chain 'E':
    Compound: Bestrophin homolog
    Species: Klebsiella pneumoniae IS53 [TaxId:1432554]
    Database cross-references and differences (RAF-indexed):
    • Uniprot W1ELP7
      • engineered mutation (181)
    Domains in SCOPe 2.08: d6iv1e_
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6iv1A (A:)
namiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapfs
llgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsyl
vafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreagkls
dttyglmdnkldelahvlggcerlattpvpfaytlilqrtvylfctllpfalvgdlhymt
pfvsvfisytflswdslaeeledpfgtaandlplnamcntiernlldmtgqhplpe

    Sequence, based on observed residues (ATOM records): (download) 
    >6iv1A (A:)
skiifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsasysrfve
arnlwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdptadlrrl
lpeervteilassmptnrilllagneigqlreagklsdttyglmdnkldelahvlggcer
lattpvpfaytlilqrtvylfctllpfalvgdlhymtpfvsvfisytflswdslaeeled
pfgtaandlplnamcntiernlldmtgq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6iv1B (B:)
namiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapfs
llgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsyl
vafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreagkls
dttyglmdnkldelahvlggcerlattpvpfaytlilqrtvylfctllpfalvgdlhymt
pfvsvfisytflswdslaeeledpfgtaandlplnamcntiernlldmtgqhplpe

    Sequence, based on observed residues (ATOM records): (download) 
    >6iv1B (B:)
skiifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsasysrfve
arnlwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdptadlrrl
lpeervteilassmptnrilllagneigqlreagklsdttyglmdnkldelahvlggcer
lattpvpfaytlilqrtvylfctllpfalvgdlhymtpfvsvfisytflswdslaeeled
pfgtaandlplnamcntiernlld

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6iv1C (C:)
namiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapfs
llgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsyl
vafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreagkls
dttyglmdnkldelahvlggcerlattpvpfaytlilqrtvylfctllpfalvgdlhymt
pfvsvfisytflswdslaeeledpfgtaandlplnamcntiernlldmtgqhplpe

    Sequence, based on observed residues (ATOM records): (download) 
    >6iv1C (C:)
kiifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsasysrfvea
rnlwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdptadlrrll
peervteilassmptnrilllagneigqlreagklsdttyglmdnkldelahvlggcerl
attpvpfaytlilqrtvylfctllpfalvgdlhymtpfvsvfisytflswdslaeeledp
fgtaandlplnamcntiernlldmtgqhp

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6iv1D (D:)
namiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapfs
llgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsyl
vafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreagkls
dttyglmdnkldelahvlggcerlattpvpfaytlilqrtvylfctllpfalvgdlhymt
pfvsvfisytflswdslaeeledpfgtaandlplnamcntiernlldmtgqhplpe

    Sequence, based on observed residues (ATOM records): (download) 
    >6iv1D (D:)
skiifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsasysrfve
arnlwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdptadlrrl
lpeervteilassmptnrilllagneigqlreagklsdttyglmdnkldelahvlggcer
lattpvpfaytlilqrtvylfctllpfalvgdlhymtpfvsvfisytflswdslaeeled
pfgtaandlplnamcntiernlldmtgq

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6iv1E (E:)
namiirpeqhwflrlfdwhgsvlskiifrlllnvlmsiiaiisyqwyeqlgihltvapfs
llgiaiaiflgfrnsasysrfvearnlwgtvliaertlvrqlrnilpaehdahrrivsyl
vafswslkhqlrktdptadlrrllpeervteilassmptnrilllagneigqlreagkls
dttyglmdnkldelahvlggcerlattpvpfaytlilqrtvylfctllpfalvgdlhymt
pfvsvfisytflswdslaeeledpfgtaandlplnamcntiernlldmtgqhplpe

    Sequence, based on observed residues (ATOM records): (download) 
    >6iv1E (E:)
iifrlllnvlmsiiaiisyqwyeqlgihltvapfsllgiaiaiflgfrnsasysrfvear
nlwgtvliaertlvrqlrnilpaehdahrrivsylvafswslkhqlrktdptadlrrllp
eervteilassmptnrilllagneigqlreagklsdttyglmdnkldelahvlggcerla
ttpvpfaytlilqrtvylfctllpfalvgdlhymtpfvsvfisytflswdslaeeledpf
gtaandlplnamcntiernlldmtgqhplp