PDB entry 6iup

View 6iup on RCSB PDB site
Description: Crystal structure of FGFR4 kinase domain in complex with compound 5
Class: transferase/inhibitor
Keywords: protein kinase, TRANSFERASE-INHIBITOR complex
Deposited on 2018-11-29, released 2019-11-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-11-06, with a file datestamp of 2019-11-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fibroblast growth factor receptor 4
    Species: Homo sapiens [TaxId:9606]
    Gene: FGFR4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P22455
      • engineered mutation (232)
    Domains in SCOPe 2.08: d6iupa_
  • Heterogens: AX0, DMS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6iupA (A:)
mgsshhhhhhssgllaglvsldlpldplwefprdrlvlgkplgegcfgqvvraeafgmdp
arpdqastvavkmlkdnasdkdladlvsemevmkligrhkniinllgvctqegplyvive
caakgnlreflrarrppgpdlspdgprssegplsfpvlvscayqvargmqylesrkcihr
dlaarnvlvtednvmkiadfglargvhhidyykktsngrlpvkwmapealfdevythqsd
vwsfgillweiftlggspypgipveelfsllreghrmdrpphcppelyglmrecwhaaps
qrptfkqlvealdkvllavsee

    Sequence, based on observed residues (ATOM records): (download) 
    >6iupA (A:)
ldlpldplwefprdrlvlgkplgegcfgqvvraeafgmdparpdqastvavkmlkasdkd
ladlvsemevmkligrhkniinllgvctqegplyvivecaakgnlreflrarrpprsseg
plsfpvlvscayqvargmqylesrkcihrdlaarnvlvtednvmkiadfglargvhhidy
ykktsngrlpvkwmapealfdevythqsdvwsfgillweiftlggspypgipveelfsll
reghrmdrpphcppelyglmrecwhaapsqrptfkqlvealdkvllav