PDB entry 6itq

View 6itq on RCSB PDB site
Description: Crystal structure of cortisol complexed with its nanobody at pH 10.5
Class: immune system
Keywords: Cortisol, Complex, Nanobody, Camelid antibody, IMMUNE SYSTEM
Deposited on 2018-11-24, released 2019-07-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-24, with a file datestamp of 2019-07-19.
Experiment type: XRAY
Resolution: 1.53 Å
R-factor: N/A
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: anti-cortisol camelid antibody
    Species: Camelus bactrianus [TaxId:9837]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ITQ (0-End)
    Domains in SCOPe 2.08: d6itqa1, d6itqa2
  • Chain 'B':
    Compound: anti-cortisol camelid antibody
    Species: Camelus bactrianus [TaxId:9837]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ITQ (0-End)
    Domains in SCOPe 2.08: d6itqb1, d6itqb2
  • Chain 'C':
    Compound: anti-cortisol camelid antibody
    Species: Camelus bactrianus [TaxId:9837]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ITQ (0-End)
    Domains in SCOPe 2.08: d6itqc1, d6itqc2
  • Chain 'D':
    Compound: anti-cortisol camelid antibody
    Species: Camelus bactrianus [TaxId:9837]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ITQ (0-End)
    Domains in SCOPe 2.08: d6itqd1, d6itqd2
  • Heterogens: HCY, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6itqA (A:)
qvqlqesgggsvqaggslrlscvvsgntgstgywawfrqgpgteregvaatytagsgtsm
tyyadsvkgrftisqdnakktlylqmnslkpedtgmyrcastrfagrwyrdseyrawgqg
tqvtvss

    Sequence, based on observed residues (ATOM records): (download) 
    >6itqA (A:)
qvqlqesgggsvqaggslrlscvvsgntgstgywawfrqgpregvaatytagstsmtyya
dsvkgrftisqdnakktlylqmnslkpedtgmyrcastrfagrwyrdseyrawgqgtqvt
vs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6itqB (B:)
qvqlqesgggsvqaggslrlscvvsgntgstgywawfrqgpgteregvaatytagsgtsm
tyyadsvkgrftisqdnakktlylqmnslkpedtgmyrcastrfagrwyrdseyrawgqg
tqvtvss

    Sequence, based on observed residues (ATOM records): (download) 
    >6itqB (B:)
qvqlqesgggsvqaggslrlscvvsgntgstgywawfrqregvaatytagstsmtyyads
vkgrftisqdnakktlylqmnslkpedtgmyrcastrfagrwyrdseyrawgqgtqvtvs

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6itqC (C:)
qvqlqesgggsvqaggslrlscvvsgntgstgywawfrqgpgteregvaatytagsgtsm
tyyadsvkgrftisqdnakktlylqmnslkpedtgmyrcastrfagrwyrdseyrawgqg
tqvtvss

    Sequence, based on observed residues (ATOM records): (download) 
    >6itqC (C:)
qvqlqesgggsvqaggslrlscvvsgntgstgywawfrqgpgteregvaatytagstsmt
yyadsvkgrftisqdnakktlylqmnslkpedtgmyrcastrfagrwyrdseyrawgqgt
qvtvs

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6itqD (D:)
qvqlqesgggsvqaggslrlscvvsgntgstgywawfrqgpgteregvaatytagsgtsm
tyyadsvkgrftisqdnakktlylqmnslkpedtgmyrcastrfagrwyrdseyrawgqg
tqvtvss

    Sequence, based on observed residues (ATOM records): (download) 
    >6itqD (D:)
qvqlqesgggsvqaggslrlscvvsgntgstgywawfrqgpregvaatytagstsmtyya
dsvkgrftisqdnakktlylqmnslkpedtgmyrcastrfagrwyrdseyrawgqgtqvt
vs