PDB entry 6isg

View 6isg on RCSB PDB site
Description: structure of 9n-i dna polymerase incorporation with dg in the active site
Deposited on 2018-11-16, released 2019-08-28
The last revision was dated 2019-08-28, with a file datestamp of 2019-08-23.
Experiment type: XRAY
Resolution: 3.4 Å
R-factor: N/A
AEROSPACI score: 0.09 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase
    Species: Thermococcus sp. 9oN-7 [TaxId:103799]
    Gene: pol, polA
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q56366 (0-End)
      • engineered mutation (140)
      • engineered mutation (142)
      • engineered mutation (484)
  • Chain 'C':
    Compound: DNA (5'-d(*gp*cp*gp*gp*ap*cp*tp*gp*cp*tp*tp*ap*cp*cp*g)-3')
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'D':
    Compound: DNA (5'-d(*gp*ap*cp*gp*gp*tp*ap*ap*gp*cp*ap*gp*tp*cp*cp*g)-3')
    Species: synthetic construct, synthetic [TaxId:32630]
  • Heterogens: PPV, CA, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6isgA (A:)
    mildtdyitengkpvirvfkkengefkieydrtfepyfyallkddsaiedvkkvtakrhg
    tvvkvkraekvqkkflgrpievwklyfnhpqdvpairdrirahpavvdiyeydipfakry
    lidkglipmegdeeltmlafaiatlyhegeefgtgpilmisyadgsearvitwkkidlpy
    vdvvstekemikrflrvvrekdpdvlityngdnfdfaylkkrceelgikftlgrdgsepk
    iqrmgdrfavevkgrihfdlypvirrtinlptytleavyeavfgkpkekvyaeeiaqawe
    sgeglervarysmedakvtyelgreffpmeaqlsrligqslwdvsrsstgnlvewfllrk
    aykrnelapnkpderelarrrggyaggyvkeperglwdnivyldfrslypsiiithnvsp
    dtlnregckeydvapevghkfckdfpgfipsllgdlleerqkikrkmkatvdplekklld
    yrqrlikilansfygyygyakarwyckecaesvtawgreyiemvireleekfgfkvlyad
    tdglhatipgadaetvkkkakeflkyinpklpglleleyegfyvrgffvtkkkyavidee
    gkittrgleivrrdwseiaketqarvleailkhgdveeavrivkevteklskyevppekl
    viheqitrdlrdykatgphvavakrlaargvkirpgtvisyivlkgsgrigdraipadef
    dptkhrydaeyyienqvlpaverilkafgyrkedlryqktkqvglgawlkvkgkklehhh
    hhh
    

    Sequence, based on observed residues (ATOM records):
    >6isgA (A:)
    mildtdyitengkpvirvfkkengefkieydrtfepyfyallkddsaiedvkkvtakrhg
    tvvkvkraekvqkkflgrpievwklyfnhpqdvpairdrirahpavvdiyeydipfakry
    lidkglipmegdeeltmlafaiatlyhegeefgtgpilmisyadgsearvitwkkidlpy
    vdvvstekemikrflrvvrekdpdvlityngdnfdfaylkkrceelgikftlgrdgsepk
    iqrmgdrfavevkgrihfdlypvirrtinlptytleavyeavfgkpkekvyaeeiaqawe
    sgeglervarysmedakvtyelgreffpmeaqlsrligqslwdvsrsstgnlvewfllrk
    aykrnelapnkpderelarrrggyaggyvkeperglwdnivyldfrslypsiiithnvsp
    dtlnregckeydvapevghkfckdfpgfipsllgdlleerqkikrkmkatvdplekklld
    yrqrlikilansfygyygyakarwyckecaesvtawgreyiemvireleekfgfkvlyad
    tdglhatipgadaetvkkkakeflkyinpklpglleleyegfyvrgffvtkkkyavidee
    gkittrgleivrrdwseiaketqarvleailkhgdveeavrivkevteklskyevppekl
    viheqitrdlrdykatgphvavakrlaargvkirpgtvisyivlkgsgrigdraipadef
    dptkhrydaeyyienqvlpaverilkafgyrked
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.