PDB entry 6isd

View 6isd on RCSB PDB site
Description: Crystal structure of Arabidopsis thaliana HPPD complexed with sulcotrione
Class: oxidoreductase/oxidoreductase inhibitor
Keywords: 4-Hydroxyphenylpyruvate dioxygenase, Slow binding inhibitors, drug design, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Deposited on 2018-11-16, released 2018-11-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-03-20, with a file datestamp of 2019-03-15.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 4-hydroxyphenylpyruvate dioxygenase
    Species: Arabidopsis thaliana [TaxId:3702]
    Gene: HPD
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6isda1, d6isda2
  • Chain 'B':
    Compound: 4-hydroxyphenylpyruvate dioxygenase
    Species: Arabidopsis thaliana [TaxId:3702]
    Gene: HPD
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6isdb1, d6isdb2
  • Heterogens: 5BQ, CO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6isdA (A:)
mghqnaavsenqnhddgaasspgfklvgfskfvrknpksdkfkvkrfhhiefwcgdatnv
arrfswglgmrfsaksdlstgnmvhasylltsgdlrflftapyspslsageikptttasi
psfdhgscrsffsshglgvravaievedaesafsisvangaipssppivlneavtiaevk
lygdvvlryvsykaedtekseflpgfervedassfpldygirrldhavgnvpelgpalty
vagftgfhqfaeftaddvgtaesglnsavlasndemvllpinepvhgtkrksqiqtyleh
negaglqhlalmsedifrtlremrkrssiggfdfmpsppptyyqnlkkrvgdvlsddqik
eceelgilvdrddqgtllqiftkplgdrptifieiiqrvgcmmkdeegkayqsggcggfg
kgnfselfksieeyektleakqlvg

    Sequence, based on observed residues (ATOM records): (download) 
    >6isdA (A:)
skfvrknpksdkfkvkrfhhiefwcgdatnvarrfswglgmrfsaksdlstgnmvhasyl
ltsgdlrflftapyspsltttasipsfdhgscrsffsshglgvravaievedaesafsis
vangaipssppivlneavtiaevklygdvvlryvsykflpgfervedfpldygirrldha
vgnvpelgpaltyvagftgfhqfaefsglnsavlasndemvllpinepvhgrksqiqtyl
ehnegaglqhlalmsedifrtlremrkrssiggfdfmpsppptyyqnlkkrvgdvlsddq
ikeceelgilvdrddqgtllqiftkplgdrptifieiiqrvgcmmyqsggcggfgkgnfs
elfksieey

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6isdB (B:)
mghqnaavsenqnhddgaasspgfklvgfskfvrknpksdkfkvkrfhhiefwcgdatnv
arrfswglgmrfsaksdlstgnmvhasylltsgdlrflftapyspslsageikptttasi
psfdhgscrsffsshglgvravaievedaesafsisvangaipssppivlneavtiaevk
lygdvvlryvsykaedtekseflpgfervedassfpldygirrldhavgnvpelgpalty
vagftgfhqfaeftaddvgtaesglnsavlasndemvllpinepvhgtkrksqiqtyleh
negaglqhlalmsedifrtlremrkrssiggfdfmpsppptyyqnlkkrvgdvlsddqik
eceelgilvdrddqgtllqiftkplgdrptifieiiqrvgcmmkdeegkayqsggcggfg
kgnfselfksieeyektleakqlvg

    Sequence, based on observed residues (ATOM records): (download) 
    >6isdB (B:)
skfvrknpksdkfkvkrfhhiefwcgdatnvarrfswglgmrfsaksdlstgnmvhasyl
ltsgdlrflftapyspsptttasipsfdhgscrsffsshglgvravaievedaesafsis
vangaipssppivlneavtiaevklygdvvlryvsykflpgfervefpldygirrldhav
gnvpelgpaltyvagftgfhqfaefesglnsavlasndemvllpinepvhgrksqiqtyl
ehnegaglqhlalmsedifrtlremrkrssiggfdfmpsppptyyqnlkkrvgdvlsddq
ikeceelgilvdrddqgtllqiftkplgdrptifieiiqrvgcmmyqsggcggfgkgnfs
elfksieeyek