PDB entry 6irs

View 6irs on RCSB PDB site
Description: human lat1-4f2hc complex incubated with jph203
Deposited on 2018-11-14, released 2019-03-27
The last revision was dated 2020-07-29, with a file datestamp of 2020-07-02.
Experiment type: EM
Resolution: 3.3 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 4F2 cell-surface antigen heavy chain
    Species: Homo sapiens [TaxId:9606]
    Gene: SLC3A2, hCG_2016598
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Large neutral amino acids transporter small subunit 1
    Species: Homo sapiens [TaxId:9606]
    Gene: SLC7A5, CD98LC, LAT1, MPE16
    Database cross-references and differences (RAF-indexed):
  • Heterogens: 3PH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6irsA (A:)
mahhhhhhhhhhsgrelqppeasiavvsiprqlpgshseagvqglsagddsetgsdcvtq
aglqllassdppalasknaevtvetgfhhvsqadiefltsidptasasgsagitgtmsqd
tevdmkevelnelepekqpmnaasgaamslagaeknglvkikvaedeaeaaaaakftgls
keellkvagspgwvrtrwallllfwlgwlgmlagavviivraprcrelpaqkwwhtgaly
rigdlqafqghgagnlaglkgrldylsslkvkglvlgpihknqkddvaqtdllqidpnfg
skedfdsllqsakkksirvildltpnyrgenswfstqvdtvatkvkdalefwlqagvdgf
qvrdienlkdassflaewqnitkgfsedrlliagtnssdlqqilsllesnkdllltssyl
sdsgstgehtkslvtqylnatgnrwcswslsqarlltsflpaqllrlyqlmlftlpgtpv
fsygdeigldaaalpgqpmeapvmlwdessfpdipgavsanmtvkgqsedpgsllslfrr
lsdqrskersllhgdfhafsagpglfsyirhwdqnerflvvlnfgdvglsaglqasdlpa
saslpakadlllstqpgreegsplelerlklepheglllrfpyaale

    Sequence, based on observed residues (ATOM records):
    >6irsA (A:)
tglskeellkvagspgwvrtrwallllfwlgwlgmlagavviivraprcrelpaqkwwht
galyrigdlqafqghgagnlaglkgrldylsslkvkglvlgpihknqkddvaqtdllqid
pnfgskedfdsllqsakkksirvildltpnyrgenswfstqvdtvatkvkdalefwlqag
vdgfqvrdienlkdassflaewqnitkgfsedrlliagtnssdlqqilsllesnkdlllt
ssylsdsgstgehtkslvtqylnatgnrwcswslsqarlltsflpaqllrlyqlmlftlp
gtpvfsygdeigldaaalpgqpmeapvmlwdessfpdipgavsanmtvkgqsedpgslls
lfrrlsdqrskersllhgdfhafsagpglfsyirhwdqnerflvvlnfgdvglsaglqas
dlpasaslpakadlllstqpgreegsplelerlklepheglllrfpyaa

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6irsB (B:)
madykddddksgpdevdasgragagpkrralaapaaeekeearekmlaaksadgsepage
gegvtlqrnitllngvaiivgtiigsgifvtptgvlkeagspglalvvwaacgvfsivga
lcyaelgttisksggdyaymlevygslpaflklwielliirpssqyivalvfatyllkpl
fptcpvpeeaaklvaclcvllltavncysvkaatrvqdafaaakllalaliillgfvqig
kgdvsnldpnfsfegtkldvgnivlalysglfayggwnylnfvteeminpyrnlplaiii
slpivtlvyvltnlayfttlsteqmlsseavavdfgnyhlgvmswiipvfvglscfgsvn
gslftssrlffvgsreghlpsilsmihpqlltpvpslvftcvmtllyafskdifsvinff
sffnwlcvalaiigmiwlrhrkpelerpikvnlalpvffilaclfliavsfwktpvecgi
gftiilsglpvyffgvwwknkpkwllqgifsttvlcqklmqvvpqet

    Sequence, based on observed residues (ATOM records):
    >6irsB (B:)
tllngvaiivgtiigsgifvtptgvlkeagspglalvvwaacgvfsivgalcyaelgtti
sksggdyaymlevygslpaflklwielliirpssqyivalvfatyllkplfptcpvpeea
aklvaclcvllltavncysvkaatrvqdafaaakllalaliillgfvqigkgdvsnldpn
fsfegtkldvgnivlalysglfayggwnylnfvteeminpyrnlplaiiislpivtlvyv
ltnlayfttlsteqmlsseavavdfgnyhlgvmswiipvfvglscfgsvngslftssrlf
fvgsreghlpsilsmihpqlltpvpslvftcvmtllyafskdifsvinffsffnwlcval
aiigmiwlrhrkpelerpikvnlalpvffilaclfliavsfwktpvecgigftiilsglp
vyffgvwwknkpkwllqgifsttvlcqklmqvvpqet