PDB entry 6iql

View 6iql on RCSB PDB site
Description: crystal structure of dopamine receptor d4 bound to the subtype- selective ligand, l745870
Deposited on 2018-11-08, released 2019-12-04
The last revision was dated 2019-12-04, with a file datestamp of 2019-11-29.
Experiment type: XRAY
Resolution: 3.5 Å
R-factor: N/A
AEROSPACI score: 0.08 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: D(4) dopamine receptor,Soluble cytochrome b562,D(4) dopamine receptor
    Species: Mus musculus [TaxId:10090]
    Gene: DRD4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51436 (Start-205)
      • engineered mutation (108)
      • engineered mutation (188)
    • Uniprot P0ABE7 (206-310)
      • engineered mutation (212)
      • engineered mutation (307)
      • linker (311)
    • Uniprot P51436 (312-End)
      • engineered mutation (325)
  • Chain 'B':
    Compound: D(4) dopamine receptor,Soluble cytochrome b562,D(4) dopamine receptor
    Species: Mus musculus [TaxId:10090]
    Gene: DRD4
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51436 (Start-205)
      • engineered mutation (108)
      • engineered mutation (168)
      • engineered mutation (188)
    • Uniprot P0ABE7 (206-310)
      • engineered mutation (212)
      • engineered mutation (307)
      • linker (311)
    • Uniprot P51436 (312-End)
      • engineered mutation (325)
  • Heterogens: L74

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6iqlA (A:)
dykddddkeftgaglggagaaalvggvlliglvlagnslvcvsvasertlqtptnyfivs
laaadlllavlvlplfvysevqggvwllsprlcdtlmamdvmlctasiwnlcaisvdrfv
avtvplrynqqgqcqllliaatwllsaavaspvvcglndvpgrdpavcrlenrdyvvyss
vcsfflpcilmlllywatfrglrrweadlednwetlndnlkviekadnaaqvkdaltkmr
aaaldaqkatppkledkspdspemkdfrhgfdilvgqiddalklanegkvkeaqaaaeql
kttrnayiqkylkitgrerkamrvlavvvgaflvcwtpffvvhitralcpacfvsprlvs
avtwlgyvnsalnpiiytifnaefrsvfrktlrlrc

    Sequence, based on observed residues (ATOM records):
    >6iqlA (A:)
gaaalvggvlliglvlagnslvcvsvasertlqtptnyfivslaaadlllavlvlplfvy
sevqggvwllsprlcdtlmamdvmlctasiwnlcaisvdrfvavtgqcqllliaatwlls
aavaspvvcglndvpgrdpenrdyvvyssvcsfflpcilmlllywatfrglrrweadled
nwetlndnlkviekadnaaqvkdaltkmraaaldaqkakdfrhgfdilvgqiddalklan
egkvkeaqaaaeqlkttrnayiqkylkitgrerkamrvlavvvgaflvcwtpffvvhitr
alcpacfvsprlvsavtwlgyvnsalnpiiytifnaefrsv

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6iqlB (B:)
dykddddkeftgaglggagaaalvggvlliglvlagnslvcvsvasertlqtptnyfivs
laaadlllavlvlplfvysevqggvwllsprlcdtlmamdvmlctasiwnlcaisvdrfv
avtvplrynqqgqcqllliaatwllsaavaspvvcglndvpgrdpavcrlenrdyvvyss
vcsfflpcilmlllywatfrglrrweadlednwetlndnlkviekadnaaqvkdaltkmr
aaaldaqkatppkledkspdspemkdfrhgfdilvgqiddalklanegkvkeaqaaaeql
kttrnayiqkylkitgrerkamrvlavvvgaflvcwtpffvvhitralcpacfvsprlvs
avtwlgyvnsalnpiiytifnaefrsvfrktlrlrc

    Sequence, based on observed residues (ATOM records):
    >6iqlB (B:)
gaaalvggvlliglvlagnslvcvsvasertlqtptnyfivslaaadlllavlvlplfvy
sevqggvwllsprlcdtlmamdvmlctasiwnlcaisvdrfvavtvgqcqllliaatwll
saavaspvvcgvcrlenrdyvvyssvcsfflpcilmlllywatfrglrrweadlednwet
lndnlkviekadnaaqvkdaltkmraaaldaqkpemkdfrhgfdilvgqiddalklaneg
kvkeaqaaaeqlkttrnayiqkylkitgrerkamrvlavvvgaflvcwtpffvvhitral
cpacfvsprlvsavtwlgyvnsalnpiiytifnaefrsvf