PDB entry 6ipb

View 6ipb on RCSB PDB site
Description: crystal structure of the cofactor-binding domain of the human phase ii drug metabolism enzyme ugt2b15
Deposited on 2018-11-02, released 2020-01-15
The last revision was dated 2020-01-22, with a file datestamp of 2020-01-17.
Experiment type: XRAY
Resolution: 1.78 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: UDP-glucuronosyltransferase 2B15
    Species: Homo sapiens [TaxId:9606]
    Gene: UGT2B15, UGT2B8
    Database cross-references and differences (RAF-indexed):
    • Uniprot P54855 (23-190)
      • expression tag (20-22)
  • Chain 'B':
    Compound: UDP-glucuronosyltransferase 2B15
    Species: Homo sapiens [TaxId:9606]
    Gene: UGT2B15, UGT2B8
    Database cross-references and differences (RAF-indexed):
    • Uniprot P54855 (23-End)
      • expression tag (20-22)
  • Chain 'C':
    Compound: UDP-glucuronosyltransferase 2B15
    Species: Homo sapiens [TaxId:9606]
    Gene: UGT2B15, UGT2B8
    Database cross-references and differences (RAF-indexed):
    • Uniprot P54855 (23-End)
      • expression tag (20-22)
  • Chain 'D':
    Compound: UDP-glucuronosyltransferase 2B15
    Species: Homo sapiens [TaxId:9606]
    Gene: UGT2B15, UGT2B8
    Database cross-references and differences (RAF-indexed):
    • Uniprot P54855 (23-End)
      • expression tag (20-22)
  • Heterogens: TLA, GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ipbA (A:)
mgsshhhhhhhhlevlfqgphmmkpakplpkemeefvqssgengivvfslgsmisnmsee
sanmiasalaqipqkvlwrfdgkkpntlgsntrlykwlpqndllghpktkafithggtng
iyeaiyhgipmvgiplfadqhdniahmkakgaalsvdirtmssrdllnalksvindpvyk
envmklsrihh

    Sequence, based on observed residues (ATOM records):
    >6ipbA (A:)
hmmkpakplpkemeefvqssgengivvfslgsmisnmseesanmiasalaqipqkvlwrf
dgkkpntlgsntrlykwlpqndllghpktkafithggtngiyeaiyhgipmvgiplfadq
hdniahmkakgaalsvdirtmssrdllnalksvindpvykenvmklsrihh

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ipbB (B:)
mgsshhhhhhhhlevlfqgphmmkpakplpkemeefvqssgengivvfslgsmisnmsee
sanmiasalaqipqkvlwrfdgkkpntlgsntrlykwlpqndllghpktkafithggtng
iyeaiyhgipmvgiplfadqhdniahmkakgaalsvdirtmssrdllnalksvindpvyk
envmklsrihh

    Sequence, based on observed residues (ATOM records):
    >6ipbB (B:)
hmmkpakplpkemeefvqssgengivvfslgsmisnmseesanmiasalaqipqkvlwrf
dgkkpntlgsntrlykwlpqndllghpktkafithggtngiyeaiyhgipmvgiplfadq
hdniahmkakgaalsvdirtmssrdllnalksvindpvykenvmklsrih

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6ipbC (C:)
mgsshhhhhhhhlevlfqgphmmkpakplpkemeefvqssgengivvfslgsmisnmsee
sanmiasalaqipqkvlwrfdgkkpntlgsntrlykwlpqndllghpktkafithggtng
iyeaiyhgipmvgiplfadqhdniahmkakgaalsvdirtmssrdllnalksvindpvyk
envmklsrihh

    Sequence, based on observed residues (ATOM records):
    >6ipbC (C:)
hmmkpakplpkemeefvqssgengivvfslgsmisnmseesanmiasalaqipqkvlwrf
dgkkpntlgsntrlykwlpqndllghpktkafithggtngiyeaiyhgipmvgiplfadq
hdniahmkakgaalsvdirtmssrdllnalksvindpvykenvmklsrih

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6ipbD (D:)
mgsshhhhhhhhlevlfqgphmmkpakplpkemeefvqssgengivvfslgsmisnmsee
sanmiasalaqipqkvlwrfdgkkpntlgsntrlykwlpqndllghpktkafithggtng
iyeaiyhgipmvgiplfadqhdniahmkakgaalsvdirtmssrdllnalksvindpvyk
envmklsrihh

    Sequence, based on observed residues (ATOM records):
    >6ipbD (D:)
hmmkpakplpkemeefvqssgengivvfslgsmisnmseesanmiasalaqipqkvlwrf
dgkkpntlgsntrlykwlpqndllghpktkafithggtngiyeaiyhgipmvgiplfadq
hdniahmkakgaalsvdirtmssrdllnalksvindpvykenvmklsri