PDB entry 6imz
View 6imz on RCSB PDB site
Description: Crystal structure of MTH1 in complex with 18-Crown-6
Class: hydrolase
Keywords: Human Nudix Hydrolase, 8-oxo-dGTP, cancer, HYDROLASE
Deposited on
2018-10-24, released
2019-10-30
The last revision prior to the SCOPe 2.07 freeze date was dated
2019-10-30, with a file datestamp of
2019-10-25.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: 7,8-dihydro-8-oxoguanine triphosphatase
Species: Homo sapiens [TaxId:9606]
Gene: NUDT1, MTH1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d6imza1, d6imza2 - Heterogens: ZN, SO4, O4B, VGH, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6imzA (A:)
masrlytlvlvlqpqrvllgmkkrgfgagrwngfggkvqegetiedgarrelqeesgltv
dalhkvgqivfefvgepelmdvhvfctdsiqgtpvesdemrpcwfqldqipfkdmwpdds
ywfplllqkkkfhgyfkfqgqdtildytlrevdtvlehhhhhh
Sequence, based on observed residues (ATOM records): (download)
>6imzA (A:)
asrlytlvlvlqpqrvllgmkkrgfgagrwngfggkvqegetiedgarrelqeesgltvd
alhkvgqivfefvgepelmdvhvfctdsiqgtpvesdemrpcwfqldqipfkdmwpddsy
wfplllqkkkfhgyfkfqgqdtildytlrevdtvlehhhhhh