PDB entry 6ika

View 6ika on RCSB PDB site
Description: hiv-1 reverse transcriptase with q151m/g112s/d113a/y115f/f116y/f160l/i159l:dna:entecavir-triphosphate ternary complex
Deposited on 2018-10-15, released 2019-01-30
The last revision was dated 2019-02-06, with a file datestamp of 2019-02-01.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HIV-1 RT p66 subunit
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot D3XFN7 (2-End)
      • engineered mutation (113-114)
      • engineered mutation (116-117)
      • engineered mutation (152)
      • engineered mutation (160-161)
      • engineered mutation (163)
      • engineered mutation (281)
  • Chain 'B':
    Compound: HIV-1 RT p51 subunit
    Species: Human immunodeficiency virus type 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12497
      • engineered mutation (177)
      • engineered mutation (295)
  • Chain 'C':
    Compound: HIV-1 RT p66 subunit
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot D3XFN7 (2-End)
      • engineered mutation (113-114)
      • engineered mutation (116-117)
      • engineered mutation (152)
      • engineered mutation (160-161)
      • engineered mutation (163)
      • engineered mutation (281)
  • Chain 'D':
    Compound: HIV-1 RT p51 subunit
    Species: Human immunodeficiency virus type 1 [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P12497
      • engineered mutation (177)
      • engineered mutation (295)
  • Chain 'E':
    Compound: DNA/RNA (38-mer)
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'F':
    Compound: DNA/RNA (38-mer)
    Species: synthetic construct, synthetic [TaxId:32630]
  • Heterogens: ET9, GOL, MG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ikaA (A:)
mvpispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpynt
pvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkqkksvtvldvsaafysv
pldkdfrkytaftipsinnetpgiryqynvlpmgwkgspallqssmtkilepfrkqnpdi
viyqymddlyvgsdleigqhrtkieelrqhllrwgfttpdkkhqkeppflwmgyelhpdk
wtvqpivlpekdswtvndiqklvgklnwasqiyagikvrqlskllrgtkaltevvpltee
aelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmk
gahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvn
tpplvklwyqlekepiigaetfyvdgaanretklgkagyvtdrgrqkvvpltdttnqkte
lqaihlalqdsglevnivtdsqyalgiiqaqpdkseselvsqiieqlikkekvylawvpa
hkgiggneqvdklvsag

    Sequence, based on observed residues (ATOM records):
    >6ikaA (A:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkqkksvtvldvsaafysvpl
dkdfrkytaftipsinnetpgiryqynvlpmgwkgspallqssmtkilepfrkqnpdivi
yqymddlyvgsdleigqhrtkieelrqhllrwgfttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiyagikvrqlskllrgtkaltevvplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkga
htndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntp
plvklwyqlekepiigaetfyvdgaanretklgkagyvtdrgrqkvvpltdttnqktelq
aihlalqdsglevnivtdsqyalgiiqaqpdkseselvsqiieqlikkekvylawvpahk
giggneqvdklvs

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ikaB (B:)
mahhhhhhalevlfqgpispietvpvklkpgmdgpkvkqwplteekikalveictemeke
gkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkqkk
svtvldvgdayfsvpldkdfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssm
tkilepfrkqnpdiviyqymddlyvgsdleigqhrtkieelrqhllrwgfttpdkkhqke
ppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiyagikvrqlskllr
gtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqe
pfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwte
ywqatwipewefvntpplvklwyq

    Sequence, based on observed residues (ATOM records):
    >6ikaB (B:)
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
kkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkqkksvtvldvgdayfsvpldkdf
rkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqym
ddlyvgsdleigqhrtkieelrqhllrwggyelhpdkwtvqpivlpekdswtvndiqklv
gklnwasqiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydp
skdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiv
iwgktpkfklpiqketweawwteywqatwipewefvntpplvklwy

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6ikaC (C:)
mvpispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpynt
pvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkqkksvtvldvsaafysv
pldkdfrkytaftipsinnetpgiryqynvlpmgwkgspallqssmtkilepfrkqnpdi
viyqymddlyvgsdleigqhrtkieelrqhllrwgfttpdkkhqkeppflwmgyelhpdk
wtvqpivlpekdswtvndiqklvgklnwasqiyagikvrqlskllrgtkaltevvpltee
aelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmk
gahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvn
tpplvklwyqlekepiigaetfyvdgaanretklgkagyvtdrgrqkvvpltdttnqkte
lqaihlalqdsglevnivtdsqyalgiiqaqpdkseselvsqiieqlikkekvylawvpa
hkgiggneqvdklvsag

    Sequence, based on observed residues (ATOM records):
    >6ikaC (C:)
pispietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpv
faikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkqkksvtvldvsaafysvpl
dkdfrkytaftipsinnetpgiryqynvlpmgwkgspallqssmtkilepfrkqnpdivi
yqymddlyvgsdleigqhrtkieelrqhllrwgfttpdkkhqkeppflwmgyelhpdkwt
vqpivlpekdswtvndiqklvgklnwasqiyagikvrqlskllrgtkaltevvplteeae
lelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkga
htndvkqlteavqkiatesiviwgktpkfklpiqketweawwteywqatwipewefvntp
plvklwyqlekepiigaetfyvdgaanretklgkagyvtdrgrqkvvpltdttnqktelq
aihlalqdsglevnivtdsqyalgiiqaqpdkseselvsqiieqlikkekvylawvpahk
giggneqvdklvs

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6ikaD (D:)
mahhhhhhalevlfqgpispietvpvklkpgmdgpkvkqwplteekikalveictemeke
gkiskigpenpyntpvfaikkkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkqkk
svtvldvgdayfsvpldkdfrkytaftipsinnetpgiryqynvlpqgwkgspaifqssm
tkilepfrkqnpdiviyqymddlyvgsdleigqhrtkieelrqhllrwgfttpdkkhqke
ppflwmgyelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiyagikvrqlskllr
gtkaltevvplteeaelelaenreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqe
pfknlktgkyarmkgahtndvkqlteavqkiatesiviwgktpkfklpiqketweawwte
ywqatwipewefvntpplvklwyq

    Sequence, based on observed residues (ATOM records):
    >6ikaD (D:)
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
kkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkqkksvtvldvgdayfsvpldkdf
rkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqym
ddlyvgsdleigqhrtkieelrqhllrwggyelhpdkwtvqpivlpekdswtvndiqklv
gklnwasqiyagikvrqlskllrgtkaltevvplteeaelelaenreilkepvhgvyydp
skdliaeiqkqgqgqwtyqiyqepfknlktgkyarmkgahtndvkqlteavqkiatesiv
iwgktpkfklpiqketweawwteywqatwipewefvntpplvklwy

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.