PDB entry 6ijl

View 6ijl on RCSB PDB site
Description: crystal structure of smyd3 in complex with covalent inhibitor 5
Deposited on 2018-10-10, released 2019-08-14
The last revision was dated 2019-08-14, with a file datestamp of 2019-08-09.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone-lysine N-methyltransferase SMYD3
    Species: Homo sapiens [TaxId:9606]
    Gene: SMYD3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9H7B4
      • engineered mutation (12)
      • engineered mutation (139)
  • Heterogens: A8U, ZN, SAM, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ijlA (A:)
    meplkvekfatanrgnglravtplrpgellfrsdplaytvckgsrgvvcdrcllgkeklm
    rcsqcrvakycsakcqkkawpdhkreckclksckpryppdsvrllgrvvfklmdgapses
    eklysfydlesninkltedrkeglrqlvmtfqhfmreeiqdasqlppafdlfeafakvic
    nsfticnaemqevgvglypsisllnhscdpncsivfngphlllravrdievgeelticyl
    dmlmtseerrkqlrdqycfecdcfrcqtqdkdadmltgdeqvwkevqeslkkieelkahw
    kweqvlamcqaiissnserlpdiniyqlkvldcamdacinlglleealfygtrtmepyri
    ffpgshpvrgvqvmkvgklqlhqgmfpqamknlrlafdimrvthgrehsliedlilllee
    cdaniras
    

    Sequence, based on observed residues (ATOM records):
    >6ijlA (A:)
    plkvekfatanrgnglravtplrpgellfrsdplaytvckgsrgvvcdrcllgkeklmrc
    sqcrvakycsakcqkkawpdhkreckclksckpryppdsvrllgrvvfklmdgapsesek
    lysfydlesninkltedrkeglrqlvmtfqhfmreeiqdasqlppafdlfeafakvicns
    fticnaemqevgvglypsisllnhscdpncsivfngphlllravrdievgeelticyldm
    lmtseerrkqlrdqycfecdcfrcqtqdkdadmltgdeqvwkevqeslkkieelkahwkw
    eqvlamcqaiissnserlpdiniyqlkvldcamdacinlglleealfygtrtmepyriff
    pgshpvrgvqvmkvgklqlhqgmfpqamknlrlafdimrvthgrehsliedlillleecd
    ani