PDB entry 6iit

View 6iit on RCSB PDB site
Description: complex structure of the hrp3 pwwp domain with both a 16-bp ta-rich dna and an h3k36me2-containing histone peptide
Deposited on 2018-10-07, released 2019-04-24
The last revision was dated 2019-04-24, with a file datestamp of 2019-04-19.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hepatoma-derived growth factor-related protein 3
    Species: Homo sapiens [TaxId:9606]
    Gene: HDGFL3, HDGF2, HDGFRP3, CGI-142
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Hepatoma-derived growth factor-related protein 3
    Species: Homo sapiens [TaxId:9606]
    Gene: HDGFL3, HDGF2, HDGFRP3, CGI-142
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9Y3E1 (1-99)
      • expression tag (0)
  • Chain 'C':
    Compound: 16-bp TA-rich DNA
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'D':
    Compound: 16-bp TA-rich DNA
    Species: synthetic construct, synthetic [TaxId:32630]
  • Chain 'E':
    Compound: H3K36me2-containing histone peptide
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6IIT (0-End)
  • Chain 'F':
    Compound: H3K36me2-containing histone peptide
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6IIT (0-End)
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6iitA (A:)
    smarprpreykagdlvfakmkgyphwparidelpegavkppankypifffgthetaflgp
    kdlfpykeykdkfgksnkrkgfneglweiennpgvkftgy
    

    Sequence, based on observed residues (ATOM records):
    >6iitA (A:)
    marprpreykagdlvfakmkgyphwparidelpegavkppankypifffgthetaflgpk
    dlfpykeykdkfgksnkrkgfneglweiennpgvkftgy
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records:
    >6iitB (B:)
    smarprpreykagdlvfakmkgyphwparidelpegavkppankypifffgthetaflgp
    kdlfpykeykdkfgksnkrkgfneglweiennpgvkftgy
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6iitE (E:)
    ggvkkphr
    

    Sequence, based on observed residues (ATOM records):
    >6iitE (E:)
    ggvkk
    

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6iitF (F:)
    ggvkkphr
    

    Sequence, based on observed residues (ATOM records):
    >6iitF (F:)
    ggvkk