PDB entry 6ii8

View 6ii8 on RCSB PDB site
Description: crystal structure of h7 hemagglutinin from a/anhui/1/2013 in complex with a human neutralizing antibody l4b-18
Deposited on 2018-10-03, released 2018-10-24
The last revision was dated 2020-07-29, with a file datestamp of 2020-07-02.
Experiment type: XRAY
Resolution: 3.32 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hemagglutinin
    Species: Influenza A virus [TaxId:1386076]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Hemagglutinin
    Species: Influenza A virus [TaxId:1663875]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Hemagglutinin
    Species: Influenza A virus [TaxId:1386076]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Hemagglutinin
    Species: Influenza A virus [TaxId:1663875]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Hemagglutinin
    Species: Influenza A virus [TaxId:1386076]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Hemagglutinin
    Species: Influenza A virus [TaxId:1663875]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Heavy chain of L4B-18 Fab
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6II8 (0-222)
  • Chain 'H':
    Compound: Heavy chain of L4B-18 Fab
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6II8 (0-222)
  • Chain 'I':
    Compound: Light chain of L4B-18 Fab
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6II8 (0-212)
  • Chain 'J':
    Compound: Heavy chain of L4B-18 Fab
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6II8 (0-End)
  • Chain 'K':
    Compound: Light chain of L4B-18 Fab
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6II8 (0-End)
  • Chain 'L':
    Compound: Light chain of L4B-18 Fab
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6II8 (0-212)
  • Heterogens: NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records:
    >6ii8A (A:)
    dkiclghhavsngtkvntltergvevvnatetvertnipricskgkrtvdlgqcgllgti
    tgppqcdqflefsadliierregsdvcypgkfvneealrqilresggidkeamgftysgi
    rtngatsacrrsgssfyaemkwllsntdnaafpqmtksykntrkspalivwgihhsvsta
    eqtklygsgnklvtvgssnyqqsfvpspgarpqvnglsgridfhwlmlnpndtvtfsfng
    afiapdrasflrgksmgiqsgvqvdancegdcyhsggtiisnlpfqnidsravgkcpryv
    kqrslllatgmknvpe
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records:
    >6ii8B (B:)
    glfgaiagfiengweglidgwygfrhqnaqgegtaadykstqsaidqitgklnrliektn
    qqfelidnefnevekqignvinwtrdsitevwsynaellvamenqhtidladsemdklye
    rvkrqlrenaeedgtgcfeifhkcdddcmasirnntydhskyreeamqnriq
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >6ii8C (C:)
    dkiclghhavsngtkvntltergvevvnatetvertnipricskgkrtvdlgqcgllgti
    tgppqcdqflefsadliierregsdvcypgkfvneealrqilresggidkeamgftysgi
    rtngatsacrrsgssfyaemkwllsntdnaafpqmtksykntrkspalivwgihhsvsta
    eqtklygsgnklvtvgssnyqqsfvpspgarpqvnglsgridfhwlmlnpndtvtfsfng
    afiapdrasflrgksmgiqsgvqvdancegdcyhsggtiisnlpfqnidsravgkcpryv
    kqrslllatgmknvpe
    

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >6ii8D (D:)
    glfgaiagfiengweglidgwygfrhqnaqgegtaadykstqsaidqitgklnrliektn
    qqfelidnefnevekqignvinwtrdsitevwsynaellvamenqhtidladsemdklye
    rvkrqlrenaeedgtgcfeifhkcdddcmasirnntydhskyreeamqnriq
    

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records:
    >6ii8E (E:)
    dkiclghhavsngtkvntltergvevvnatetvertnipricskgkrtvdlgqcgllgti
    tgppqcdqflefsadliierregsdvcypgkfvneealrqilresggidkeamgftysgi
    rtngatsacrrsgssfyaemkwllsntdnaafpqmtksykntrkspalivwgihhsvsta
    eqtklygsgnklvtvgssnyqqsfvpspgarpqvnglsgridfhwlmlnpndtvtfsfng
    afiapdrasflrgksmgiqsgvqvdancegdcyhsggtiisnlpfqnidsravgkcpryv
    kqrslllatgmknvpe
    

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6ii8F (F:)
    glfgaiagfiengweglidgwygfrhqnaqgegtaadykstqsaidqitgklnrliektn
    qqfelidnefnevekqignvinwtrdsitevwsynaellvamenqhtidladsemdklye
    rvkrqlrenaeedgtgcfeifhkcdddcmasirnntydhskyreeamqnriq
    

    Sequence, based on observed residues (ATOM records):
    >6ii8F (F:)
    glfgaiagfiengweglidgwygfrhqnaqgegtaadykstqsaidqitgklnrliektn
    qqfelidnefnevekqignvinwtrdsitevwsynaellvamenqhtidladsemdklye
    rvkrqlrenaeedgtgcfeifhkcdddcmasirnntydhskyreeamqnri
    

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records:
    >6ii8G (G:)
    evqlvesggglvqpggslrlscaasgftfssyamswvrqapgkglewvsaisgsggstyy
    adsvkgrftisrdnskntlylqmnslraedtavyycakdrllwfgellfegfdywgqgtl
    vtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpa
    vlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkv
    

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6ii8H (H:)
    evqlvesggglvqpggslrlscaasgftfssyamswvrqapgkglewvsaisgsggstyy
    adsvkgrftisrdnskntlylqmnslraedtavyycakdrllwfgellfegfdywgqgtl
    vtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpa
    vlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkv
    

    Sequence, based on observed residues (ATOM records):
    >6ii8H (H:)
    evqlvesggglvqpggslrlscaasgftfssyamswvrqapgkglewvsaisgsggstyy
    adsvkgrftisrdnskntlylqmnslraedtavyycakdrllwfgellfegfdywgqgtl
    vtvssastkgpsvfplapggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
    lyslssvvtvpssslgtqtyicnvnhkpsntkvdkkv
    

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records:
    >6ii8I (I:)
    nfmltqphsvsespgktvtisctrssgsiasnyvqwyqqrpgsspttviyednqrpsgvp
    drfsgsidsssnsasltisglktedeadyycqsydssnvvfgggtkltvlgqpkaapsvt
    lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
    ylsltpeqwkshrsyscqvthegstvektvapt
    

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6ii8J (J:)
    evqlvesggglvqpggslrlscaasgftfssyamswvrqapgkglewvsaisgsggstyy
    adsvkgrftisrdnskntlylqmnslraedtavyycakdrllwfgellfegfdywgqgtl
    vtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpa
    vlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkv
    

    Sequence, based on observed residues (ATOM records):
    >6ii8J (J:)
    evqlvesggglvqplrlscaasgftfssyamswvrqapgkglewvsaisgsggstyyads
    vkgrftisrdnskntlylqmnslraedtavyycakdrllwfgellfegfdywgqgtlv
    

  • Chain 'K':
    Sequence, based on SEQRES records:
    >6ii8K (K:)
    nfmltqphsvsespgktvtisctrssgsiasnyvqwyqqrpgsspttviyednqrpsgvp
    drfsgsidsssnsasltisglktedeadyycqsydssnvvfgggtkltvlgqpkaapsvt
    lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
    ylsltpeqwkshrsyscqvthegstvektvapt
    

    Sequence, based on observed residues (ATOM records):
    >6ii8K (K:)
    nfmltqphsvstisctrssgsiasnyvqwyqqrpgsspttviyednqrpsgvpdrfsgsi
    dsssnsasltisglktedeadyycqsydssnvvfgggtkl
    

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records:
    >6ii8L (L:)
    nfmltqphsvsespgktvtisctrssgsiasnyvqwyqqrpgsspttviyednqrpsgvp
    drfsgsidsssnsasltisglktedeadyycqsydssnvvfgggtkltvlgqpkaapsvt
    lfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaass
    ylsltpeqwkshrsyscqvthegstvektvapt