PDB entry 6ii7

View 6ii7 on RCSB PDB site
Description: Crystal structure of Plasmodium falciparum adenosine deaminase C27Q+L227I mutant co-complexed with Zn ion, hypoxanthine and inosine
Class: hydrolase
Keywords: TIM barrel, HYDROLASE
Deposited on 2018-10-03, released 2019-05-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-08, with a file datestamp of 2019-05-10.
Experiment type: XRAY
Resolution: 2.48 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: adenosine deaminase
    Species: Plasmodium falciparum 3D7 [TaxId:36329]
    Gene: PF3D7_1029600
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q8IJA9 (Start-366)
      • engineered mutation (26)
      • engineered mutation (226)
    Domains in SCOPe 2.08: d6ii7a_
  • Heterogens: NOS, HPA, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ii7A (A:)
mncknmdtsyeiinyltkdeldidlsqmdkkerykiwkrlpkcelhchldvcfsvdffln
virkyniqpnmsdeeiidyylfskpgksldefvekalrltdiyidytvvedlakhavfnk
ykegvvlmefryspsfmsfkhnldkdliheaivkglneavalleykiqvgllctgdggls
hermkeaaefcikhkkdfvgydhaghevdlkpfkdifdnireegisisvhagedvsipnl
nslytainllhvkrighgirvsesqelidlvkekdillevcpisnvllnnvksmdthpir
mlydagvkvsvnsddpgmfltnitdnyeelythlnftladfmkmnlwavqksfvdpdikn
kiiskyf

    Sequence, based on observed residues (ATOM records): (download) 
    >6ii7A (A:)
inyltkdeldidlsqmdkkerykiwkrlpkcelhchldvcfsvdfflnvirkyniqpnms
deeiidyylfskpgksldefvekalrltdiyidytvvedlakhavfnkykegvvlmefry
spsfmsfkhnldkdliheaivkglneavalleykiqvgllctgdgglshermkeaaefci
khkkdfvgydhaghevdlkpfkdifdnireegisisvhagedvsipnlnslytainllhv
krighgirvsesqelidlvkekdillevcpisnvllnnvksmdthpirmlydagvkvsvn
sddpgmfltnitdnyeelythlnftladfmkmnlwavqksfvdpdiknkiiskyf