PDB entry 6ihz

View 6ihz on RCSB PDB site
Description: the atomic structure of shp2 e76a mutant
Deposited on 2018-10-03, released 2019-10-09
Made obsolete by 7emn on 2021-05-05

The last revision was dated 2021-05-05, with a file datestamp of 2021-04-30.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein phosphatase non-receptor type 11
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPN11, PTP2C, SHPTP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q06124
      • engineered mutation (75)
  • Chain 'B':
    Compound: Tyrosine-protein phosphatase non-receptor type 11
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPN11, PTP2C, SHPTP2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q06124
      • engineered mutation (75)

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ihzA (A:)
mtsrrwfhpnitgveaenllltrgvdgsflarpsksnpgdftlsvrrngavthikiqntg
dyydlyggekfatlaalvqyymehhgqlkekngdvielkyplncadptserwfhghlsgk
eaeklltekgkhgsflvresqshpgdfvlsvrtgddkgesndgkskvthvmircqelkyd
vgggerfdsltdlvehykknpmvetlgtvlqlkqplnttrinaaeiesrvrelsklaett
dkvkqgfweefetlqqqeckllysrkegqrqenknknryknilpfdhtrvvlhdgdpnep
vsdyinaniimpefetkcnnskpkksyiatqgclqntvndfwrmvfqensrvivmttkev
ergkskcvkywpdeyalkeygvmrvrnvkesaahdytlrelklskvgqgntertvwqyhf
rtwpdhgvpsdpggvldfleevhhkqesimdagpvvvhcsagigrtgtfividilidiir
ekgvdcdidvpktiqmvrsqrsgmvqteaqyrfiymavqhyietlqrrieeeqk

    Sequence, based on observed residues (ATOM records):
    >6ihzA (A:)
srrwfhpnitgveaenllltrgvdgsflarpspgdftlsvrrngavthikiqntgdyydl
yggekfatlaalvqyymehhgqlkedvielkyplncadptserwfhghlsgkeaekllte
kgkhgsflvresqshpgdfvlsvrtgddgkskvthvmircqelkydvgggerfdsltdlv
ehykknpmvetlgtvlqlkqplnttrinaaeiesrvrelskqgfweefetlqqqecklly
srkegqrqenknknryknilpfdhtrvvlhdgdppvsdyinaniimpekksyiatqgclq
ntvndfwrmvfqensrvivmttkevergkskcvkywpdeyalkeygvmrvrnvkesaahd
ytlrelklskvgqgntertvwqyhfrtwpdhgvpsdpggvldfleevhhkqesimdagpv
vvhcsagigrtgtfividilidiirekgvdcdidvpktiqmvrsqrsgmvqteaqyrfiy
mavqhyietlqrrie

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ihzB (B:)
mtsrrwfhpnitgveaenllltrgvdgsflarpsksnpgdftlsvrrngavthikiqntg
dyydlyggekfatlaalvqyymehhgqlkekngdvielkyplncadptserwfhghlsgk
eaeklltekgkhgsflvresqshpgdfvlsvrtgddkgesndgkskvthvmircqelkyd
vgggerfdsltdlvehykknpmvetlgtvlqlkqplnttrinaaeiesrvrelsklaett
dkvkqgfweefetlqqqeckllysrkegqrqenknknryknilpfdhtrvvlhdgdpnep
vsdyinaniimpefetkcnnskpkksyiatqgclqntvndfwrmvfqensrvivmttkev
ergkskcvkywpdeyalkeygvmrvrnvkesaahdytlrelklskvgqgntertvwqyhf
rtwpdhgvpsdpggvldfleevhhkqesimdagpvvvhcsagigrtgtfividilidiir
ekgvdcdidvpktiqmvrsqrsgmvqteaqyrfiymavqhyietlqrrieeeqk

    Sequence, based on observed residues (ATOM records):
    >6ihzB (B:)
tsrrwfhpnitgveaenllltrgvdgsflarpsksnpgdftlsvrrngavthikiqntgd
yydlyggekfatlaalvqyymehhgqlkegdvielkyplncadptserwfhghlsgkeae
klltekgkhgsflvresqshpgdfvlsvrtgdgkskvthvmircqelkydvgggerfdsl
tdlvehykknpmvetlgtvlqlkqplnttrinaaeiesrvrelskqgfweefetlqqqec
kllysrkegqrqenknknryknilpfdhtrvvlhdgdppvsdyinaniimpekksyiatq
gclqntvndfwrmvfqensrvivmttkevergkskcvkywpdeyalkeygvmrvrnvkes
aahdytlrelklskvgqgntertvwqyhfrtwpdhgvpsdpggvldfleevhhkqesimd
agpvvvhcsagigrtgtfividilidiirekgvdcdidvpktiqmvrsqrsgmvqteaqy
rfiymavqhyietlqrrie