PDB entry 6ihi

View 6ihi on RCSB PDB site
Description: Crystal structure of RasADH 3B3/I91V from Ralstonia.sp in complex with NADPH and A6O
Class: hydrolase/inhibitor
Keywords: OXIDOREDUCTASE, KRED, BIOCATALYST, HYDROLASE-INHIBITOR complex
Deposited on 2018-09-30, released 2019-10-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-10-16, with a file datestamp of 2019-10-11.
Experiment type: XRAY
Resolution: 1.78 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Alclohol dehydrogenase
    Species: Ralstonia sp. [TaxId:54061]
    Database cross-references and differences (RAF-indexed):
    • Uniprot C0IR58 (Start-248)
      • engineered mutation (90)
      • engineered mutation (186-187)
      • engineered mutation (204)
    Domains in SCOPe 2.08: d6ihia_
  • Chain 'B':
    Compound: Alclohol dehydrogenase
    Species: Ralstonia sp. [TaxId:54061]
    Database cross-references and differences (RAF-indexed):
    • Uniprot C0IR58 (0-248)
      • engineered mutation (90)
      • engineered mutation (186)
      • engineered mutation (204)
    Domains in SCOPe 2.08: d6ihib_
  • Chain 'C':
    Compound: Alclohol dehydrogenase
    Species: Ralstonia sp. [TaxId:54061]
    Database cross-references and differences (RAF-indexed):
    • Uniprot C0IR58 (0-248)
      • engineered mutation (90)
      • engineered mutation (186-187)
      • engineered mutation (204)
    Domains in SCOPe 2.08: d6ihic_
  • Chain 'D':
    Compound: Alclohol dehydrogenase
    Species: Ralstonia sp. [TaxId:54061]
    Database cross-references and differences (RAF-indexed):
    • Uniprot C0IR58 (0-248)
      • engineered mutation (90)
      • engineered mutation (186-187)
      • engineered mutation (204)
    Domains in SCOPe 2.08: d6ihid_
  • Heterogens: NAP, A6O, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ihiA (A:)
myrllnktavitggnsgiglatakrfvaegayvfivgrrrkeleqaaaeigrnvtavkad
vtkledldrlyaivreqrgsidvlfansgaveqktleeitpehydrtfdvnvrgliftvq
kalpllrdggsviltssvagvlglqahdtysaakaavrslartwttelkgrsirvnavsp
gaidtpslenqvstqeeadelrakaaaatplgrvgrpeelaaavlflasddssyvagiel
fvdggltqv

    Sequence, based on observed residues (ATOM records): (download) 
    >6ihiA (A:)
yrllnktavitggnsgiglatakrfvaegayvfivgrrrkeleqaaaeigrnvtavkadv
tkledldrlyaivreqrgsidvlfansgaveqktleeitpehydrtfdvnvrgliftvqk
alpllrdggsviltssvagvlglqahdtysaakaavrslartwttelkgrsirvnavspg
aidtpslenqvstqeeadelrakaaaatplgrvgrpeelaaavlflasddssyvagielf
vdggltqv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6ihiB (B:)
myrllnktavitggnsgiglatakrfvaegayvfivgrrrkeleqaaaeigrnvtavkad
vtkledldrlyaivreqrgsidvlfansgaveqktleeitpehydrtfdvnvrgliftvq
kalpllrdggsviltssvagvlglqahdtysaakaavrslartwttelkgrsirvnavsp
gaidtpslenqvstqeeadelrakaaaatplgrvgrpeelaaavlflasddssyvagiel
fvdggltqv

    Sequence, based on observed residues (ATOM records): (download) 
    >6ihiB (B:)
myrllnktavitggnsgiglatakrfvaegayvfivgrrrkeleqaaaeigrnvtavkad
vtkledldrlyaivreqrgsidvlfansgaveqktleeitpehydrtfdvnvrgliftvq
kalpllrdggsviltssvagvlglqahdtysaakaavrslartwttelkgrsirvnavsp
gaidtpsrakaaaatplgrvgrpeelaaavlflasddssyvagielfvdggltqv

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6ihiC (C:)
myrllnktavitggnsgiglatakrfvaegayvfivgrrrkeleqaaaeigrnvtavkad
vtkledldrlyaivreqrgsidvlfansgaveqktleeitpehydrtfdvnvrgliftvq
kalpllrdggsviltssvagvlglqahdtysaakaavrslartwttelkgrsirvnavsp
gaidtpslenqvstqeeadelrakaaaatplgrvgrpeelaaavlflasddssyvagiel
fvdggltqv

    Sequence, based on observed residues (ATOM records): (download) 
    >6ihiC (C:)
myrllnktavitggnsgiglatakrfvaegayvfivgrrrkeleqaaaeigrnvtavkad
vtkledldrlyaivreqrgsidvlfansgaveqktleeitpehydrtfdvnvrgliftvq
kalpllrdggsviltssvagvlglqahdtysaakaavrslartwttelkgrsirvnavsp
gaidtpsldelrakaaaatplgrvgrpeelaaavlflasddssyvagielfvdggltqv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6ihiD (D:)
myrllnktavitggnsgiglatakrfvaegayvfivgrrrkeleqaaaeigrnvtavkad
vtkledldrlyaivreqrgsidvlfansgaveqktleeitpehydrtfdvnvrgliftvq
kalpllrdggsviltssvagvlglqahdtysaakaavrslartwttelkgrsirvnavsp
gaidtpslenqvstqeeadelrakaaaatplgrvgrpeelaaavlflasddssyvagiel
fvdggltqv

    Sequence, based on observed residues (ATOM records): (download) 
    >6ihiD (D:)
myrllnktavitggnsgiglatakrfvaegayvfivgrrrkeleqaaaeigrnvtavkad
vtkledldrlyaivreqrgsidvlfansgaveqktleeitpehydrtfdvnvrgliftvq
kalpllrdggsviltssvagvlglqahdtysaakaavrslartwttelkgrsirvnavsp
gaidtpslrakaaaatplgrvgrpeelaaavlflasddssyvagielfvdggltqv