PDB entry 6igl

View 6igl on RCSB PDB site
Description: crystal structure of human etb receptor in complex with irl1620
Deposited on 2018-09-25, released 2018-11-21
The last revision was dated 2018-11-21, with a file datestamp of 2018-11-16.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Endothelin receptor type B,Endolysin,Endothelin receptor type B
    Species: Homo sapiens [TaxId:9606]
    Gene: EDNRB, ETRB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24530 (Start-240)
      • engineered mutation (61)
      • engineered mutation (91)
      • engineered mutation (207)
    • Uniprot A0A097J809 (241-400)
      • engineered mutation (293)
      • engineered mutation (336)
    • Uniprot P24530 (401-End)
      • engineered mutation (432)
      • engineered mutation (471)
      • engineered mutation (486)
      • engineered mutation (490)
  • Chain 'B':
    Compound: irl1620
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6IGL (0-14)
  • Heterogens: CIT, SO4, OLC, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6iglA (A:)
ggglapaevpkgdrtagspprtispppcqgpieiketfkyintvvsclvfvlgiignstl
lyiiyknkcmrngpniliaslalgdllhiviaipinvykllaedwpfgaemcklvpfiqk
asvgitvlslcalsidryravaswsrikgigvpkwtaveivliwvvsvvlavpeaigfdi
itmdykgsylricllhpvqktafmqfyatakdwwlfsfyfclplaitaffytlmtcemlr
knifemlrideglrlkiykdtegyytigighlltkspslnaakseldkaigrntngvitk
deaeklfnqdvdaavrgilrnaklkpvydsldavrraalinmvfqmgetgvagftnslrm
lqqkrwdeaavnlaksrwynqtpnrakrvittfrtgtwdaylndhlkqrrevaktvfclv
lvfalcwlplhlarilkltlynqndpnrcellsfllvldyiginmaslnscanpialylv
skrfknafksalccwaqs

    Sequence, based on observed residues (ATOM records):
    >6iglA (A:)
pppcqgpieiketfkyintvvsclvfvlgiignstllyiiyknkcmrngpniliaslalg
dllhiviaipinvykllaedwpfgaemcklvpfiqkasvgitvlslcalsidryravasw
srikgigvpkwtaveivliwvvsvvlavpeaigfdiitmdykgsylricllhpvqktafm
qfyatakdwwlfsfyfclplaitaffytlmtcemlrknifemlrideglrlkiykdtegy
ytigighlltkspslnaakseldkaigrntngvitkdeaeklfnqdvdaavrgilrnakl
kpvydsldavrraalinmvfqmgetgvagftnslrmlqqkrwdeaavnlaksrwynqtpn
rakrvittfrtgtwdaylndhlkqrrevaktvfclvlvfalcwlplhlarilkltlynqn
dpnrcellsfllvldyiginmaslnscanpialylvskrfknafksalc

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records:
    >6iglB (B:)
xdeeavyfahldiiw