PDB entry 6iga

View 6iga on RCSB PDB site
Description: Crystal structure of argininosuccinate lyase from Mycobacterium tuberculosis
Class: lyase
Keywords: argininosuccinate lyase, fumarate, tetramer, LYASE
Deposited on 2018-09-25, released 2019-02-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-02-13, with a file datestamp of 2019-02-08.
Experiment type: XRAY
Resolution: 2.78 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Argininosuccinate Lyase
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: argH, Rv1659, MTCY06H11.24
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6igaa_
  • Chain 'B':
    Compound: Argininosuccinate Lyase
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: argH, Rv1659, MTCY06H11.24
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6igab_
  • Chain 'C':
    Compound: Argininosuccinate Lyase
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: argH, Rv1659, MTCY06H11.24
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6igac_
  • Chain 'D':
    Compound: Argininosuccinate Lyase
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: argH, Rv1659, MTCY06H11.24
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6igad_
  • Heterogens: SO4

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6igaA (A:)
mstnegslwggrfaggpsdalaalsksthfdwvlapydltasrahtmvlfragllteeqr
dgllagldslaqdvadgsfgplvtdedvhaalerglidrvgpdlggrlragrsrndqvaa
lfrmwlrdavrrvatgvldvvgalaeqaaahpsaimpgkthlqsaqpillahhllahahp
llrdldrivdfdkraavspygsgalagsslgldpdaiaadlgfsaaadnsvdataardfa
aeaafvfamiavdlsrlaediivwsstefgyvtlhdswstgssimpqkknpdiaelargk
sgrlignlagllatlkaqplaynrdlqedkepvfdsvaqlelllpamaglvasltfnvqr
maelapagytlatdlaewlvrqgvpfrsaheaagaavraaeqrgvglqeltddelaaisp
eltpqvrevltiegsvsardcrggtapgrvaeqlnaigeaaerlrrqlvr

    Sequence, based on observed residues (ATOM records): (download) 
    >6igaA (A:)
gpsdalaalsksthfdwvlapydltasrahtmvlfragllteeqrdgllagldslaqdva
dgsfgplvtdedvhaalerglidrvgpdlggrlragrsrndqvaalfrmwlrdavrrvat
gvldvvgalaeqaaahpsaimpgkthlqsaqpillahhllahahpllrdldrivdfdkra
avspygsgalagsslgldpdaiaadlgfsaaadnsvdataardfaaeaafvfamiavdls
rlaediivwsstefgyvtlhdswstgssimpqkknpdiaelargksgrlignlagllatl
kaqplaynrdlqedkepvfdsvaqlelllpamaglvasltfnvqrmaelapagytlatdl
aewlvrqgvpfrsaheaagaavraaeqrgvglqeltddelaaispeltpqvrevltiegs
vsardcrggtapgrvaeqlnaigeaaerlrrqlvr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6igaB (B:)
mstnegslwggrfaggpsdalaalsksthfdwvlapydltasrahtmvlfragllteeqr
dgllagldslaqdvadgsfgplvtdedvhaalerglidrvgpdlggrlragrsrndqvaa
lfrmwlrdavrrvatgvldvvgalaeqaaahpsaimpgkthlqsaqpillahhllahahp
llrdldrivdfdkraavspygsgalagsslgldpdaiaadlgfsaaadnsvdataardfa
aeaafvfamiavdlsrlaediivwsstefgyvtlhdswstgssimpqkknpdiaelargk
sgrlignlagllatlkaqplaynrdlqedkepvfdsvaqlelllpamaglvasltfnvqr
maelapagytlatdlaewlvrqgvpfrsaheaagaavraaeqrgvglqeltddelaaisp
eltpqvrevltiegsvsardcrggtapgrvaeqlnaigeaaerlrrqlvr

    Sequence, based on observed residues (ATOM records): (download) 
    >6igaB (B:)
gpsdalaalsksthfdwvlapydltasrahtmvlfragllteeqrdgllagldslaqdva
dgsfgplvtdedvhaalerglidrvgpdlggrlragrsrndqvaalfrmwlrdavrrvat
gvldvvgalaeqaaahpsaimpgkthlqsaqpillahhllahahpllrdldrivdfdkra
avspygsgalagsslgldpdaiaadlgfsaaadnsvdataardfaaeaafvfamiavdls
rlaediivwsstefgyvtlhdswstgssimpqkknpdiaelargksgrlignlagllatl
kaqplaynrdlqedkepvfdsvaqlelllpamaglvasltfnvqrmaelapagytlatdl
aewlvrqgvpfrsaheaagaavraaeqrgvglqeltddelaaispeltpqvrevltiegs
vsardcrggtapgrvaeqlnaigeaaerlrrqlvr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6igaC (C:)
mstnegslwggrfaggpsdalaalsksthfdwvlapydltasrahtmvlfragllteeqr
dgllagldslaqdvadgsfgplvtdedvhaalerglidrvgpdlggrlragrsrndqvaa
lfrmwlrdavrrvatgvldvvgalaeqaaahpsaimpgkthlqsaqpillahhllahahp
llrdldrivdfdkraavspygsgalagsslgldpdaiaadlgfsaaadnsvdataardfa
aeaafvfamiavdlsrlaediivwsstefgyvtlhdswstgssimpqkknpdiaelargk
sgrlignlagllatlkaqplaynrdlqedkepvfdsvaqlelllpamaglvasltfnvqr
maelapagytlatdlaewlvrqgvpfrsaheaagaavraaeqrgvglqeltddelaaisp
eltpqvrevltiegsvsardcrggtapgrvaeqlnaigeaaerlrrqlvr

    Sequence, based on observed residues (ATOM records): (download) 
    >6igaC (C:)
gpsdalaalsksthfdwvlapydltasrahtmvlfragllteeqrdgllagldslaqdva
dgsfgplvtdedvhaalerglidrvgpdlggrlragrsrndqvaalfrmwlrdavrrvat
gvldvvgalaeqaaahpsaimpgkthlqsaqpillahhllahahpllrdldrivdfdkra
avspygsgalagsslgldpdaiaadlgfsaaadnsvdataardfaaeaafvfamiavdls
rlaediivwsstefgyvtlhdswstgssimpqkknpdiaelargksgrlignlagllatl
kaqplaynrdlqedkepvfdsvaqlelllpamaglvasltfnvqrmaelapagytlatdl
aewlvrqgvpfrsaheaagaavraaeqrgvglqeltddelaaispeltpqvrevltiegs
vsardcrggtapgrvaeqlnaigeaaerlrrqlvr

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6igaD (D:)
mstnegslwggrfaggpsdalaalsksthfdwvlapydltasrahtmvlfragllteeqr
dgllagldslaqdvadgsfgplvtdedvhaalerglidrvgpdlggrlragrsrndqvaa
lfrmwlrdavrrvatgvldvvgalaeqaaahpsaimpgkthlqsaqpillahhllahahp
llrdldrivdfdkraavspygsgalagsslgldpdaiaadlgfsaaadnsvdataardfa
aeaafvfamiavdlsrlaediivwsstefgyvtlhdswstgssimpqkknpdiaelargk
sgrlignlagllatlkaqplaynrdlqedkepvfdsvaqlelllpamaglvasltfnvqr
maelapagytlatdlaewlvrqgvpfrsaheaagaavraaeqrgvglqeltddelaaisp
eltpqvrevltiegsvsardcrggtapgrvaeqlnaigeaaerlrrqlvr

    Sequence, based on observed residues (ATOM records): (download) 
    >6igaD (D:)
gpsdalaalsksthfdwvlapydltasrahtmvlfragllteeqrdgllagldslaqdva
dgsfgplvtdedvhaalerglidrvgpdlggrlragrsrndqvaalfrmwlrdavrrvat
gvldvvgalaeqaaahpsaimpgkthlqsaqpillahhllahahpllrdldrivdfdkra
avspygsgalagsslgldpdaiaadlgfsaaadnsvdataardfaaeaafvfamiavdls
rlaediivwsstefgyvtlhdswstgssimpqkknpdiaelargksgrlignlagllatl
kaqplaynrdlqedkepvfdsvaqlelllpamaglvasltfnvqrmaelapagytlatdl
aewlvrqgvpfrsaheaagaavraaeqrgvglqeltddelaaispeltpqvrevltiegs
vsardcrggtapgrvaeqlnaigeaaerlrrqlvr