PDB entry 6ifj
View 6ifj on RCSB PDB site
Description: structure of bispecific fc
Deposited on
2018-09-20, released
2019-09-25
The last revision was dated
2020-07-29, with a file datestamp of
2020-07-02.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.29
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Immunoglobulin gamma-1 heavy chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P0DOX5
- engineered mutation (141)
- engineered mutation (193)
- Chain 'B':
Compound: Immunoglobulin gamma-1 heavy chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P0DOX5
- engineered mutation (154)
- Chain 'C':
Compound: 13-mer peptide
Species: synthetic construct, synthetic [TaxId:32630]
Database cross-references and differences (RAF-indexed):
- Chain 'D':
Compound: 13-mer peptide
Species: synthetic construct, synthetic [TaxId:32630]
Database cross-references and differences (RAF-indexed):
- Heterogens: GOL, HOH
PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.
- Chain 'A':
Sequence, based on SEQRES records:
>6ifjA (A:)
epkscdkthtcppcpapellggpsvflfppkpkdtlmisrtpevtcvvvdvshedpevkf
nwyvdgvevhnaktkpreeqynstyrvvsvltvlhqdwlngkeykckvsnkalpapiekt
iskakgqprepqvytlppsrdkltknqvsltclvkgfypsdiavewesngqpennykttp
pvldsdgsfflysrltvdksrwqqgnvfscsvmhealhnhytqkslslspgk
Sequence, based on observed residues (ATOM records):
>6ifjA (A:)
ggpsvflfppkpkdtlmisrtpevtcvvvdvshedpevkfnwyvdgvevhnaktkpreeq
ynstyrvvsvltvlhqdwlngkeykckvsnkalpapiektiskakgqprepqvytlppsr
dkltknqvsltclvkgfypsdiavewesngqpennykttppvldsdgsfflysrltvdks
rwqqgnvfscsvmhealhnhytqkslsls
- Chain 'B':
Sequence, based on SEQRES records:
>6ifjB (B:)
epkscdkthtcppcpapellggpsvflfppkpkdtlmisrtpevtcvvvdvshedpevkf
nwyvdgvevhnaktkpreeqynstyrvvsvltvlhqdwlngkeykckvsnkalpapiekt
iskakgqprepqvytlppsrdeltknqvsltclvegfypsdiavewesngqpennykttp
pvldsdgsfflyskltvdksrwqqgnvfscsvmhealhnhytqkslslspgk
Sequence, based on observed residues (ATOM records):
>6ifjB (B:)
lggpsvflfppkpkdtlmisrtpevtcvvvdvshedpevkfnwyvdgvevhnaktkpree
qynstyrvvsvltvlhqdwlngkeykckvsnkalpapiektiskakgqprepqvytlpps
rdeltknqvsltclvegfypsdiavewesngqpennykttppvldsdgsfflyskltvdk
srwqqgnvfscsvmhealhnhytqkslsls
- Chain 'C':
Sequence; same for both SEQRES and ATOM records:
>6ifjC (C:)
dcawhlgelvwct
- Chain 'D':
Sequence; same for both SEQRES and ATOM records:
>6ifjD (D:)
dcawhlgelvwct