PDB entry 6ifj

View 6ifj on RCSB PDB site
Description: structure of bispecific fc
Deposited on 2018-09-20, released 2019-09-25
The last revision was dated 2020-07-29, with a file datestamp of 2020-07-02.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Immunoglobulin gamma-1 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DOX5
      • engineered mutation (141)
      • engineered mutation (193)
  • Chain 'B':
    Compound: Immunoglobulin gamma-1 heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DOX5
      • engineered mutation (154)
  • Chain 'C':
    Compound: 13-mer peptide
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6IFJ (0-12)
  • Chain 'D':
    Compound: 13-mer peptide
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6IFJ (0-12)
  • Heterogens: GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ifjA (A:)
    epkscdkthtcppcpapellggpsvflfppkpkdtlmisrtpevtcvvvdvshedpevkf
    nwyvdgvevhnaktkpreeqynstyrvvsvltvlhqdwlngkeykckvsnkalpapiekt
    iskakgqprepqvytlppsrdkltknqvsltclvkgfypsdiavewesngqpennykttp
    pvldsdgsfflysrltvdksrwqqgnvfscsvmhealhnhytqkslslspgk
    

    Sequence, based on observed residues (ATOM records):
    >6ifjA (A:)
    ggpsvflfppkpkdtlmisrtpevtcvvvdvshedpevkfnwyvdgvevhnaktkpreeq
    ynstyrvvsvltvlhqdwlngkeykckvsnkalpapiektiskakgqprepqvytlppsr
    dkltknqvsltclvkgfypsdiavewesngqpennykttppvldsdgsfflysrltvdks
    rwqqgnvfscsvmhealhnhytqkslsls
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ifjB (B:)
    epkscdkthtcppcpapellggpsvflfppkpkdtlmisrtpevtcvvvdvshedpevkf
    nwyvdgvevhnaktkpreeqynstyrvvsvltvlhqdwlngkeykckvsnkalpapiekt
    iskakgqprepqvytlppsrdeltknqvsltclvegfypsdiavewesngqpennykttp
    pvldsdgsfflyskltvdksrwqqgnvfscsvmhealhnhytqkslslspgk
    

    Sequence, based on observed residues (ATOM records):
    >6ifjB (B:)
    lggpsvflfppkpkdtlmisrtpevtcvvvdvshedpevkfnwyvdgvevhnaktkpree
    qynstyrvvsvltvlhqdwlngkeykckvsnkalpapiektiskakgqprepqvytlpps
    rdeltknqvsltclvegfypsdiavewesngqpennykttppvldsdgsfflyskltvdk
    srwqqgnvfscsvmhealhnhytqkslsls
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >6ifjC (C:)
    dcawhlgelvwct
    

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >6ifjD (D:)
    dcawhlgelvwct