PDB entry 6if5

View 6if5 on RCSB PDB site
Description: crystal structure of monkey tlr7 in complex with 2',3'-cgmp (guanosine 2',3'-cyclic phosphate)
Deposited on 2018-09-18, released 2019-01-30
The last revision was dated 2020-07-29, with a file datestamp of 2020-07-02.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Toll-like receptor 7
    Species: Macaca mulatta [TaxId:9544]
    Gene: TLR7
    Database cross-references and differences (RAF-indexed):
    • Uniprot B3Y653 (4-End)
      • engineered mutation (144)
      • engineered mutation (366)
      • engineered mutation (776)
  • Chain 'B':
    Compound: Toll-like receptor 7
    Species: Macaca mulatta [TaxId:9544]
    Gene: TLR7
    Database cross-references and differences (RAF-indexed):
    • Uniprot B3Y653 (4-End)
      • engineered mutation (144)
      • engineered mutation (366)
      • engineered mutation (776)
  • Heterogens: NAG, SO4, 23G, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6if5A (A:)
rspwarwfpktlpcdvtldvsknhvivdctdkhlteipggiptnttnltltinhipdisp
asfhrlvhlveidfrcncvpirlgsksnmcprrlqikprsfsgltylkslyldgnqllei
pqglppslqllsleannifsirkeqltelanieilylgqncyyrnpcyvsysiekdafln
ltklkvlslkdnnvttvptvlpstltelylynnmiaeiqeddfnnlnqlqildlsgncpr
cynapfpctpcknnsplqipvnafdaltelkvlrlhsnslqhvpprwfkninnlqeldls
qnflakeigdakflhflpnliqldlsfnfelqvyrasmnlsqafsslkslkilrirgyvf
kelksfqlsplhnlqnlevldlgtnfikianlsmfkqfkrlkvidlsvnkispsgdslvp
rgssnartsvesyepqvleqlyyfrydkyarscrfknkeasftsvqescykygqtldlsk
nsiffikssdfqhlsflkclnlsgnlisqtlngsefqplaelryldfsnnrldllhstaf
eelrklevldissnshyfqsegithmlnftknlkvlqklmmndndissstsrtmeseslr
tlefrgnhldvlwrdgdnrylqlfknllkleeldisknslsflpsgvfdgmppnlknlsl
aknglksfiweklrylknletldlshnqlttvperlsncsrslknlilknnqirsltkyf
lqdafqlryldlssnkiqmiqktsfpenvlnnlkmlllhhnrflctcdavwfvwwvqhte
vtipylatdvtcvgpgahkgqsvisldlytceldltneflvpr

    Sequence, based on observed residues (ATOM records):
    >6if5A (A:)
arwfpktlpcdvtldvsknhvivdctdkhlteipggiptnttnltltinhipdispasfh
rlvhlveidfrcncvpirlgsksnmcprrlqikprsfsgltylkslyldgnqlleipqgl
ppslqllsleannifsirkeqltelanieilylgqncyyrnpcyvsysiekdaflnltkl
kvlslkdnnvttvptvlpstltelylynnmiaeiqeddfnnlnqlqildlsgncprcyna
pfpctpcknnsplqipvnafdaltelkvlrlhsnslqhvpprwfkninnlqeldlsqnfl
akeigdakflhflpnliqldlsfnfelqvyrasmnlsqafsslkslkilrirgyvfkelk
sfqlsplhnlqnlevldlgtnfikianlsmfkqfkrlkvidlsvnkispvleqlyyfryd
kyarscrfscykygqtldlsknsiffikssdfqhlsflkclnlsgnlisqtlngsefqpl
aelryldfsnnrldllhstafeelrklevldissnshyfqsegithmlnftknlkvlqkl
mmndndissstsrtmeseslrtlefrgnhldvlwrdgdnrylqlfknllkleeldiskns
lsflpsgvfdgmppnlknlslaknglksfiweklrylknletldlshnqlttvperlsnc
srslknlilknnqirsltkyflqdafqlryldlssnkiqmiqktsfpenvlnnlkmlllh
hnrflctcdavwfvwwvqhtevtipylatdvtcvgpgahkgqsvisldlytcel

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6if5B (B:)
rspwarwfpktlpcdvtldvsknhvivdctdkhlteipggiptnttnltltinhipdisp
asfhrlvhlveidfrcncvpirlgsksnmcprrlqikprsfsgltylkslyldgnqllei
pqglppslqllsleannifsirkeqltelanieilylgqncyyrnpcyvsysiekdafln
ltklkvlslkdnnvttvptvlpstltelylynnmiaeiqeddfnnlnqlqildlsgncpr
cynapfpctpcknnsplqipvnafdaltelkvlrlhsnslqhvpprwfkninnlqeldls
qnflakeigdakflhflpnliqldlsfnfelqvyrasmnlsqafsslkslkilrirgyvf
kelksfqlsplhnlqnlevldlgtnfikianlsmfkqfkrlkvidlsvnkispsgdslvp
rgssnartsvesyepqvleqlyyfrydkyarscrfknkeasftsvqescykygqtldlsk
nsiffikssdfqhlsflkclnlsgnlisqtlngsefqplaelryldfsnnrldllhstaf
eelrklevldissnshyfqsegithmlnftknlkvlqklmmndndissstsrtmeseslr
tlefrgnhldvlwrdgdnrylqlfknllkleeldisknslsflpsgvfdgmppnlknlsl
aknglksfiweklrylknletldlshnqlttvperlsncsrslknlilknnqirsltkyf
lqdafqlryldlssnkiqmiqktsfpenvlnnlkmlllhhnrflctcdavwfvwwvqhte
vtipylatdvtcvgpgahkgqsvisldlytceldltneflvpr

    Sequence, based on observed residues (ATOM records):
    >6if5B (B:)
arwfpktlpcdvtldvsknhvivdctdkhlteipggiptnttnltltinhipdispasfh
rlvhlveidfrcncvpirlgsksnmcprrlqikprsfsgltylkslyldgnqlleipqgl
ppslqllsleannifsirkeqltelanieilylgqncyyrnpcyvsysiekdaflnltkl
kvlslkdnnvttvptvlpstltelylynnmiaeiqeddfnnlnqlqildlsgncprcyna
pfpctpcknnsplqipvnafdaltelkvlrlhsnslqhvpprwfkninnlqeldlsqnfl
akeigdakflhflpnliqldlsfnfelqvyrasmnlsqafsslkslkilrirgyvfkelk
sfqlsplhnlqnlevldlgtnfikianlsmfkqfkrlkvidlsvnkispvleqlyyfryd
kyarscrscykygqtldlsknsiffikssdfqhlsflkclnlsgnlisqtlngsefqpla
elryldfsnnrldllhstafeelrklevldissnshyfqsegithmlnftknlkvlqklm
mndndissstsrtmeseslrtlefrgnhldvlwrdgdnrylqlfknllkleeldisknsl
sflpsgvfdgmppnlknlslaknglksfiweklrylknletldlshnqlttvperlsncs
rslknlilknnqirsltkyflqdafqlryldlssnkiqmiqktsfpenvlnnlkmlllhh
nrflctcdavwfvwwvqhtevtipylatdvtcvgpgahkgqsvisldlytcel