PDB entry 6ie2

View 6ie2 on RCSB PDB site
Description: crystal structure of methyladenine demethylase
Deposited on 2018-09-13, released 2019-09-18
The last revision was dated 2020-07-08, with a file datestamp of 2020-07-03.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nucleic acid dioxygenase ALKBH1
    Species: Homo sapiens [TaxId:9606]
    Gene: ALKBH1, ABH, ABH1, ALKBH
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Nucleic acid dioxygenase ALKBH1
    Species: Homo sapiens [TaxId:9606]
    Gene: ALKBH1, ABH, ABH1, ALKBH
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Nucleic acid dioxygenase ALKBH1
    Species: Homo sapiens [TaxId:9606]
    Gene: ALKBH1, ABH, ABH1, ALKBH
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Nucleic acid dioxygenase ALKBH1
    Species: Homo sapiens [TaxId:9606]
    Gene: ALKBH1, ABH, ABH1, ALKBH
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Nucleic acid dioxygenase ALKBH1
    Species: Homo sapiens [TaxId:9606]
    Gene: ALKBH1, ABH, ABH1, ALKBH
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Nucleic acid dioxygenase ALKBH1
    Species: Homo sapiens [TaxId:9606]
    Gene: ALKBH1, ABH, ABH1, ALKBH
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Nucleic acid dioxygenase ALKBH1
    Species: Homo sapiens [TaxId:9606]
    Gene: ALKBH1, ABH, ABH1, ALKBH
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Nucleic acid dioxygenase ALKBH1
    Species: Homo sapiens [TaxId:9606]
    Gene: ALKBH1, ABH, ABH1, ALKBH
    Database cross-references and differences (RAF-indexed):
  • Heterogens: MN, AKG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ie2A (A:)
mgkmaaavgsvatlatepgedafrklfrfyrqsrpgtadlegvidfsaahaargkgpgaq
kviksqlnvssvseqnayraglqpvskwqayglkgypgfifipnpflpgyqwhwvkqclk
lysqkpnvcnldkhmskeetqdlweqskeflrykeatkrrprslleklrwvtvgyhynwd
skkysadhytpfpsdlgflseqvaaacgfedfraeagilnyyrldstlgihvdrseldhs
kpllsfsfgqsaifllgglqrdeaptamfmhsgdimimsgfsrllnhavprvlpnpegeg
lphcleaplpavlprdsmvepcsmedwqvcasylktarvnmtvrqvlatdqnfplepied
ekrdistegfchlddqnsevkrarinpds

    Sequence, based on observed residues (ATOM records):
    >6ie2A (A:)
gedafrklfrfyrqsrpgtadlegvidfsagaqkviksqlnvssvseqnayraglqpvsk
wqayglkgypgfifipnpflpgyqwhwvkqclklysqkpnvcnldkhmskeetqdlweqs
keflrykerslleklrwvtvgyhynwdskkysadhytpfpsdlgflseqvaaacgfedfr
aeagilnyyrldstlgihvdrseldhskpllsfsfgqsaifllgglqrdeaptamfmhsg
dimimsgfsrllnhavprvlpnpegeglphcleaplpavlprdsmvepcsmedwqvcasy
lktarvnmtvrqvlatdqnfp

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ie2B (B:)
mgkmaaavgsvatlatepgedafrklfrfyrqsrpgtadlegvidfsaahaargkgpgaq
kviksqlnvssvseqnayraglqpvskwqayglkgypgfifipnpflpgyqwhwvkqclk
lysqkpnvcnldkhmskeetqdlweqskeflrykeatkrrprslleklrwvtvgyhynwd
skkysadhytpfpsdlgflseqvaaacgfedfraeagilnyyrldstlgihvdrseldhs
kpllsfsfgqsaifllgglqrdeaptamfmhsgdimimsgfsrllnhavprvlpnpegeg
lphcleaplpavlprdsmvepcsmedwqvcasylktarvnmtvrqvlatdqnfplepied
ekrdistegfchlddqnsevkrarinpds

    Sequence, based on observed residues (ATOM records):
    >6ie2B (B:)
gedafrklfrfyrqsrpgtadlegvidfsagaqkviksqlnvssvseqnayraglqpvsk
wqayglkgypgfifipnpflpgyqwhwvkqclklysqkpnvcnldkhmskeetqdlweqs
keflrykerslleklrwvtvgyhynwdskkysadhytpfpsdlgflseqvaaacgfedfr
aeagilnyyrldstlgihvdrseldhskpllsfsfgqsaifllgglqrdeaptamfmhsg
dimimsgfsrllnhavprvlpnpegeglphcleaplpavlprdsmvepcsmedwqvcasy
lktarvnmtvrqvlatdqnfple

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6ie2C (C:)
mgkmaaavgsvatlatepgedafrklfrfyrqsrpgtadlegvidfsaahaargkgpgaq
kviksqlnvssvseqnayraglqpvskwqayglkgypgfifipnpflpgyqwhwvkqclk
lysqkpnvcnldkhmskeetqdlweqskeflrykeatkrrprslleklrwvtvgyhynwd
skkysadhytpfpsdlgflseqvaaacgfedfraeagilnyyrldstlgihvdrseldhs
kpllsfsfgqsaifllgglqrdeaptamfmhsgdimimsgfsrllnhavprvlpnpegeg
lphcleaplpavlprdsmvepcsmedwqvcasylktarvnmtvrqvlatdqnfplepied
ekrdistegfchlddqnsevkrarinpds

    Sequence, based on observed residues (ATOM records):
    >6ie2C (C:)
gedafrklfrfyrqsrpgtadlegvidfsagaqkviksqlnvssvseqnayraglqpvsk
wqayglkgypgfifipnpflpgyqwhwvkqclklysqkpnvcnldkhmskeetqdlweqs
keflrykerslleklrwvtvgyhynwdskkysadhytpfpsdlgflseqvaaacgfedfr
aeagilnyyrldstlgihvdrseldhskpllsfsfgqsaifllgglqrdeaptamfmhsg
dimimsgfsrllnhavprvlpnpegeglphcleaplpavlprdsmvepcsmedwqvcasy
lktarvnmtvrqvlatdqnfple

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6ie2D (D:)
mgkmaaavgsvatlatepgedafrklfrfyrqsrpgtadlegvidfsaahaargkgpgaq
kviksqlnvssvseqnayraglqpvskwqayglkgypgfifipnpflpgyqwhwvkqclk
lysqkpnvcnldkhmskeetqdlweqskeflrykeatkrrprslleklrwvtvgyhynwd
skkysadhytpfpsdlgflseqvaaacgfedfraeagilnyyrldstlgihvdrseldhs
kpllsfsfgqsaifllgglqrdeaptamfmhsgdimimsgfsrllnhavprvlpnpegeg
lphcleaplpavlprdsmvepcsmedwqvcasylktarvnmtvrqvlatdqnfplepied
ekrdistegfchlddqnsevkrarinpds

    Sequence, based on observed residues (ATOM records):
    >6ie2D (D:)
gedafrklfrfyrqsrpgtadlegvidfsagaqkviksqlnvssvseqnayraglqpvsk
wqayglkgypgfifipnpflpgyqwhwvkqclklysqkpnvcnldkhmskeetqdlweqs
keflrykerslleklrwvtvgyhynwdskkysadhytpfpsdlgflseqvaaacgfedfr
aeagilnyyrldstlgihvdrseldhskpllsfsfgqsaifllgglqrdeaptamfmhsg
dimimsgfsrllnhavprvlpnpegeglphcleaplpavlprdsmvepcsmedwqvcasy
lktarvnmtvrqvlatdqnfple

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6ie2E (E:)
mgkmaaavgsvatlatepgedafrklfrfyrqsrpgtadlegvidfsaahaargkgpgaq
kviksqlnvssvseqnayraglqpvskwqayglkgypgfifipnpflpgyqwhwvkqclk
lysqkpnvcnldkhmskeetqdlweqskeflrykeatkrrprslleklrwvtvgyhynwd
skkysadhytpfpsdlgflseqvaaacgfedfraeagilnyyrldstlgihvdrseldhs
kpllsfsfgqsaifllgglqrdeaptamfmhsgdimimsgfsrllnhavprvlpnpegeg
lphcleaplpavlprdsmvepcsmedwqvcasylktarvnmtvrqvlatdqnfplepied
ekrdistegfchlddqnsevkrarinpds

    Sequence, based on observed residues (ATOM records):
    >6ie2E (E:)
gedafrklfrfyrqsrpgtadlegvidfsaagaqkviksqlnvssvseqnayraglqpvs
kwqayglkgypgfifipnpflpgyqwhwvkqclklysqkpnvcnldkhmskeetqdlweq
skeflrykrslleklrwvtvgyhynwdskkysadhytpfpsdlgflseqvaaacgfedfr
aeagilnyyrldstlgihvdrseldhskpllsfsfgqsaifllgglqrdeaptamfmhsg
dimimsgfsrllnhavprvlpnpegeglphcleaplpavlprdsmvepcsmedwqvcasy
lktarvnmtvrqvlatd

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6ie2F (F:)
mgkmaaavgsvatlatepgedafrklfrfyrqsrpgtadlegvidfsaahaargkgpgaq
kviksqlnvssvseqnayraglqpvskwqayglkgypgfifipnpflpgyqwhwvkqclk
lysqkpnvcnldkhmskeetqdlweqskeflrykeatkrrprslleklrwvtvgyhynwd
skkysadhytpfpsdlgflseqvaaacgfedfraeagilnyyrldstlgihvdrseldhs
kpllsfsfgqsaifllgglqrdeaptamfmhsgdimimsgfsrllnhavprvlpnpegeg
lphcleaplpavlprdsmvepcsmedwqvcasylktarvnmtvrqvlatdqnfplepied
ekrdistegfchlddqnsevkrarinpds

    Sequence, based on observed residues (ATOM records):
    >6ie2F (F:)
gedafrklfrfyrqsrpgtadlegvidfsaagaqkviksqlnvssvseqnayraglqpvs
kwqayglkgypgfifipnpflpgyqwhwvkqclklysqkpnvcnldkhmskeetqdlweq
skeflrykerslleklrwvtvgyhynwdskkysadhytpfpsdlgflseqvaaacgfedf
raeagilnyyrldstlgihvdrseldhskpllsfsfgqsaifllgglqrdeaptamfmhs
gdimimsgfsrllnhavprvlpnpegeglphcleaplpavlprdsmvepcsmedwqvcas
ylktarvnmtvrqvlatdqnfple

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6ie2G (G:)
mgkmaaavgsvatlatepgedafrklfrfyrqsrpgtadlegvidfsaahaargkgpgaq
kviksqlnvssvseqnayraglqpvskwqayglkgypgfifipnpflpgyqwhwvkqclk
lysqkpnvcnldkhmskeetqdlweqskeflrykeatkrrprslleklrwvtvgyhynwd
skkysadhytpfpsdlgflseqvaaacgfedfraeagilnyyrldstlgihvdrseldhs
kpllsfsfgqsaifllgglqrdeaptamfmhsgdimimsgfsrllnhavprvlpnpegeg
lphcleaplpavlprdsmvepcsmedwqvcasylktarvnmtvrqvlatdqnfplepied
ekrdistegfchlddqnsevkrarinpds

    Sequence, based on observed residues (ATOM records):
    >6ie2G (G:)
gedafrklfrfyrqsrpgtadlegvidfsaagaqkviksqlnvssvseqnayraglqpvs
kwqayglkgypgfifipnpflpgyqwhwvkqclklysqkpnvcnldkhmskeetqdlweq
skeflrykerslleklrwvtvgyhynwdskkysadhytpfpsdlgflseqvaaacgfedf
raeagilnyyrldstlgihvdrseldhskpllsfsfgqsaifllgglqrdeaptamfmhs
gdimimsgfsrllnhavprvlpnpegeglphcleaplpavlprdsmvepcsmedwqvcas
ylktarvnmtvrqvlatdqnfpl

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6ie2H (H:)
mgkmaaavgsvatlatepgedafrklfrfyrqsrpgtadlegvidfsaahaargkgpgaq
kviksqlnvssvseqnayraglqpvskwqayglkgypgfifipnpflpgyqwhwvkqclk
lysqkpnvcnldkhmskeetqdlweqskeflrykeatkrrprslleklrwvtvgyhynwd
skkysadhytpfpsdlgflseqvaaacgfedfraeagilnyyrldstlgihvdrseldhs
kpllsfsfgqsaifllgglqrdeaptamfmhsgdimimsgfsrllnhavprvlpnpegeg
lphcleaplpavlprdsmvepcsmedwqvcasylktarvnmtvrqvlatdqnfplepied
ekrdistegfchlddqnsevkrarinpds

    Sequence, based on observed residues (ATOM records):
    >6ie2H (H:)
gedafrklfrfyrqsrpgtadlegvidfsaagaqkviksqlnvssvseqnayraglqpvs
kwqayglkgypgfifipnpflpgyqwhwvkqclklysqkpnvcnldkhmskeetqdlweq
skeflrykerslleklrwvtvgyhynwdskkysadhytpfpsdlgflseqvaaacgfedf
raeagilnyyrldstlgihvdrseldhskpllsfsfgqsaifllgglqrdeaptamfmhs
gdimimsgfsrllnhavprvlpnpegeglphcleaplpavlprdsmvepcsmedwqvcas
ylktarvnmtvrqvlatdqnfple