PDB entry 6id4

View 6id4 on RCSB PDB site
Description: defining the structural basis for human alloantibody binding to human leukocyte antigen allele hla-a*11:01
Deposited on 2018-09-08, released 2019-02-06
The last revision was dated 2020-10-28, with a file datestamp of 2020-10-23.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: MHC class I antigen
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-A
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ID4 (0-221)
  • Chain 'D':
    Compound: light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ID4
  • Chain 'E':
    Compound: MHC class I antigen
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-A
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Gene: B2M, CDABP0092, HDCMA22P
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ID4 (0-221)
  • Chain 'L':
    Compound: light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ID4
  • Chain 'T':
    Compound: peptide
    Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ID4 (0-8)
  • Chain 'U':
    Compound: peptide
    Species: Human immunodeficiency virus 1, synthetic [TaxId:11676]
    Database cross-references and differences (RAF-indexed):
    • PDB 6ID4 (0-8)
  • Heterogens: GOL, PEG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6id4A (A:)
    mgshsmryfytsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpey
    wdqetrnvkaqsqtdrvdlgtlrgyynqsedgshtiqimygcdvgpdgrflrgyrqdayd
    gkdyialnedlrswtaadmaaqitkrkweaahaaeqqraylegrcvewlrrylengketl
    qrtdppkthmthhpisdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdg
    tfqkwaavvvpsgeeqrytchvqheglpkpltlrwe
    

    Sequence, based on observed residues (ATOM records):
    >6id4A (A:)
    gshsmryfytsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
    dqetrnvkaqsqtdrvdlgtlrgyynqsedgshtiqimygcdvgpdgrflrgyrqdaydg
    kdyialnedlrswtaadmaaqitkrkweaahaaeqqraylegrcvewlrrylengketlq
    rtdppkthmthhpisdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdgt
    fqkwaavvvpsgeeqrytchvqheglpkpltlrw
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6id4B (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

    Sequence, based on observed residues (ATOM records):
    >6id4B (B:)
    iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
    sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6id4C (C:)
    evqlvqsgaevkkpgasvkvsckasgytftgyymhwvrqapgqglewmgwinpnsggtsy
    aqkfqgrvtmtrdtststvymelsslrsedtavyycarvttviagpvfdywgqgtlvtvs
    sastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
    sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk
    

    Sequence, based on observed residues (ATOM records):
    >6id4C (C:)
    evqlvqsgaevkkpgasvkvsckasgytftgyymhwvrqapgqglewmgwinpnsggtsy
    aqkfqgrvtmtrdtststvymelsslrsedtavyycarvttviagpvfdywgqgtlvtvs
    sastkgpsvfplapsgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglysl
    ssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk
    

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6id4D (D:)
    qavltqpsslsaspgasasltctlrsginvgpyniywyqqkpgsppqylmryksdpdkhq
    gsavpsrfsgskdasanagillisglqsedeadyycmiwhnnawvfgggtkltvlgqpka
    apsvtlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnk
    yaassylsltpeqwkshksyscqvthegstvektvaptecs
    

    Sequence, based on observed residues (ATOM records):
    >6id4D (D:)
    vltqpsslsaspgasasltctlrsginvgpyniywyqqkpgsppqylmryksdpdkhqgs
    avpsrfsgskdasanagillisglqsedeadyycmiwhnnawvfgggtkltvlgqpkaap
    svtlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkya
    assylsltpeqwkshksyscqvthegstvektvap
    

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6id4E (E:)
    mgshsmryfytsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpey
    wdqetrnvkaqsqtdrvdlgtlrgyynqsedgshtiqimygcdvgpdgrflrgyrqdayd
    gkdyialnedlrswtaadmaaqitkrkweaahaaeqqraylegrcvewlrrylengketl
    qrtdppkthmthhpisdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdg
    tfqkwaavvvpsgeeqrytchvqheglpkpltlrwe
    

    Sequence, based on observed residues (ATOM records):
    >6id4E (E:)
    gshsmryfytsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
    dqetrnvkaqsqtdrvdlgtlrgyynqsedgshtiqimygcdvgpdgrflrgyrqdaydg
    kdyialnedlrswtaadmaaqitkrkweaahaaeqqraylegrcvewlrrylengketlq
    rtdppkthmthhpisdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdgt
    fqkwaavvvpsgeeqrytchvqheglpkpltlrwe
    

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6id4F (F:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

    Sequence, based on observed residues (ATOM records):
    >6id4F (F:)
    iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
    sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6id4H (H:)
    evqlvqsgaevkkpgasvkvsckasgytftgyymhwvrqapgqglewmgwinpnsggtsy
    aqkfqgrvtmtrdtststvymelsslrsedtavyycarvttviagpvfdywgqgtlvtvs
    sastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
    sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk
    

    Sequence, based on observed residues (ATOM records):
    >6id4H (H:)
    evqlvqsgaevkkpgasvkvsckasgytftgyymhwvrqapgqglewmgwinpnsggtsy
    aqkfqgrvtmtrdtststvymelsslrsedtavyycarvttviagpvfdywgqgtlvtvs
    sastkgpsvfplapsgtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglysl
    ssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk
    

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6id4L (L:)
    qavltqpsslsaspgasasltctlrsginvgpyniywyqqkpgsppqylmryksdpdkhq
    gsavpsrfsgskdasanagillisglqsedeadyycmiwhnnawvfgggtkltvlgqpka
    apsvtlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnk
    yaassylsltpeqwkshksyscqvthegstvektvaptecs
    

    Sequence, based on observed residues (ATOM records):
    >6id4L (L:)
    avltqpsslsaspgasasltctlrsginvgpyniywyqqkpgsppqylmryksdpdkhqg
    savpsrfsgskdasanagillisglqsedeadyycmiwhnnawvfgggtkltvlgqpkaa
    psvtlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnky
    aassylsltpeqwkshksyscqvthegstvektvap
    

  • Chain 'T':
    Sequence; same for both SEQRES and ATOM records:
    >6id4T (T:)
    aifqssmtk
    

  • Chain 'U':
    Sequence; same for both SEQRES and ATOM records:
    >6id4U (U:)
    aifqssmtk