PDB entry 6icv

View 6icv on RCSB PDB site
Description: structure of setd3 bound to sah and unmodified actin
Deposited on 2018-09-07, released 2019-02-27
The last revision was dated 2019-03-06, with a file datestamp of 2019-03-01.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone-lysine N-methyltransferase setd3
    Species: Homo sapiens [TaxId:9606]
    Gene: SETD3, C14orf154
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Histone-lysine N-methyltransferase setd3
    Species: Homo sapiens [TaxId:9606]
    Gene: SETD3, C14orf154
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Actin, cytoplasmic 1
    Species: Homo sapiens [TaxId:9606]
    Gene: ACTB
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Actin, cytoplasmic 1
    Species: Homo sapiens [TaxId:9606]
    Gene: ACTB
    Database cross-references and differences (RAF-indexed):
  • Heterogens: SAH, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6icvA (A:)
gmgkksrvktqksgtgatatvspkeilnltsellqkcsspapgpgkeweeyvqirtlvek
irkkqkglsvtfdgkredyfpdlmkwasengasvegfemvnfkeegfglratrdikaeel
flwvprkllmtvesaknsvlgplysqdrilqamgnialafhllceraspnsfwqpyiqtl
pseydtplyfeedevrylqstqaihdvfsqykntarqyayfykviqthphanklplkdsf
tyedyrwavssvmtrqnqiptedgsrvtlaliplwdmcnhtnglittgynleddrcecva
lqdfrageqiyifygtrsnaefvihsgfffdnnshdrvkiklgvsksdrlyamkaevlar
agiptssvfalhfteppisaqllaflrvfcmteeelkehllgdsaidriftlgnsefpvs
wdnevklwtfledraslllktykttieedksvlknhdlsvrakmaiklrlgekeilekav
ksaavnreyyrqqmeekaplpkye

    Sequence, based on observed residues (ATOM records):
    >6icvA (A:)
spkeilnltsellqkcsspapgkeweeyvqirtlvekirkkqkglsvtfdgkredyfpdl
mkwasengasvegfemvnfkeegfglratrdikaeelflwvprkllmtvesaknsvlgpl
ysqdrilqamgnialafhllceraspnsfwqpyiqtlpseydtplyfeedevrylqstqa
ihdvfsqykntarqyayfykviqthphanklplkdsftyedyrwavssvmtrqnqipted
gsrvtlaliplwdmcnhtnglittgynleddrcecvalqdfrageqiyifygtrsnaefv
ihsgfffdnnshdrvkiklgvsksdrlyamkaevlaragiptssvfalhfteppisaqll
aflrvfcmteeelkehllgdsaidriftlgnsefpvswdnevklwtfledraslllktyk
ttieedksvlknhdlsvrakmaiklrlgekeilekavksaavnreyyrqqmeekaplpky

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6icvB (B:)
gmgkksrvktqksgtgatatvspkeilnltsellqkcsspapgpgkeweeyvqirtlvek
irkkqkglsvtfdgkredyfpdlmkwasengasvegfemvnfkeegfglratrdikaeel
flwvprkllmtvesaknsvlgplysqdrilqamgnialafhllceraspnsfwqpyiqtl
pseydtplyfeedevrylqstqaihdvfsqykntarqyayfykviqthphanklplkdsf
tyedyrwavssvmtrqnqiptedgsrvtlaliplwdmcnhtnglittgynleddrcecva
lqdfrageqiyifygtrsnaefvihsgfffdnnshdrvkiklgvsksdrlyamkaevlar
agiptssvfalhfteppisaqllaflrvfcmteeelkehllgdsaidriftlgnsefpvs
wdnevklwtfledraslllktykttieedksvlknhdlsvrakmaiklrlgekeilekav
ksaavnreyyrqqmeekaplpkye

    Sequence, based on observed residues (ATOM records):
    >6icvB (B:)
spkeilnltsellqkcsspapgkeweeyvqirtlvekirkkqkglsvtfdgkredyfpdl
mkwasengasvegfemvnfkeegfglratrdikaeelflwvprkllmtvesaknsvlgpl
ysqdrilqamgnialafhllceraspnsfwqpyiqtlpseydtplyfeedevrylqstqa
ihdvfsqykntarqyayfykviqthphanklplkdsftyedyrwavssvmtrqnqipted
gsrvtlaliplwdmcnhtnglittgynleddrcecvalqdfrageqiyifygtrsnaefv
ihsgfffdnnshdrvkiklgvsksdrlyamkaevlaragiptssvfalhfteppisaqll
aflrvfcmteeelkehllgdsaidriftlgnsefpvswdnevklwtfledraslllktyk
ttieedksvlknhdlsvrakmaiklrlgekeilekavksaavnreyyrqqmeekaplpk

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6icvC (C:)
tlkypiehgivtnwddmekiwhh

    Sequence, based on observed residues (ATOM records):
    >6icvC (C:)
lkypiehgivtnwddme

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6icvD (D:)
tlkypiehgivtnwddmekiwhh

    Sequence, based on observed residues (ATOM records):
    >6icvD (D:)
lkypiehgivtnwddme