PDB entry 6ict

View 6ict on RCSB PDB site
Description: structure of setd3 bound to sah and methylated actin
Deposited on 2018-09-07, released 2019-02-27
The last revision was dated 2019-03-06, with a file datestamp of 2019-03-01.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone-lysine N-methyltransferase setd3
    Species: Homo sapiens [TaxId:9606]
    Gene: SETD3, C14orf154
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Histone-lysine N-methyltransferase setd3
    Species: Homo sapiens [TaxId:9606]
    Gene: SETD3, C14orf154
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Histone-lysine N-methyltransferase setd3
    Species: Homo sapiens [TaxId:9606]
    Gene: SETD3, C14orf154
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Histone-lysine N-methyltransferase setd3
    Species: Homo sapiens [TaxId:9606]
    Gene: SETD3, C14orf154
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Actin, cytoplasmic 1
    Species: Homo sapiens [TaxId:9606]
    Gene: ACTB
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Actin, cytoplasmic 1
    Species: Homo sapiens [TaxId:9606]
    Gene: ACTB
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Actin, cytoplasmic 1
    Species: Homo sapiens [TaxId:9606]
    Gene: ACTB
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: Actin, cytoplasmic 1
    Species: Homo sapiens [TaxId:9606]
    Gene: ACTB
    Database cross-references and differences (RAF-indexed):
  • Heterogens: SAH, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ictA (A:)
gmgkksrvktqksgtgatatvspkeilnltsellqkcsspapgpgkeweeyvqirtlvek
irkkqkglsvtfdgkredyfpdlmkwasengasvegfemvnfkeegfglratrdikaeel
flwvprkllmtvesaknsvlgplysqdrilqamgnialafhllceraspnsfwqpyiqtl
pseydtplyfeedevrylqstqaihdvfsqykntarqyayfykviqthphanklplkdsf
tyedyrwavssvmtrqnqiptedgsrvtlaliplwdmcnhtnglittgynleddrcecva
lqdfrageqiyifygtrsnaefvihsgfffdnnshdrvkiklgvsksdrlyamkaevlar
agiptssvfalhfteppisaqllaflrvfcmteeelkehllgdsaidriftlgnsefpvs
wdnevklwtfledraslllktykttieedksvlknhdlsvrakmaiklrlgekeilekav
ksaavnreyyrqqmeekaplpkye

    Sequence, based on observed residues (ATOM records):
    >6ictA (A:)
pkeilnltsellqkcsspapgkeweeyvqirtlvekirkkqkglsvtfdgkredyfpdlm
kwasengasvegfemvnfkeegfglratrdikaeelflwvprkllmtvesaknsvlgply
sqdrilqamgnialafhllceraspnsfwqpyiqtlpseydtplyfeedevrylqstqai
hdvfsqykntarqyayfykviqthphanklplkdsftyedyrwavssvmtrqnqiptedg
srvtlaliplwdmcnhtnglittgynleddrcecvalqdfrageqiyifygtrsnaefvi
hsgfffdnnshdrvkiklgvsksdrlyamkaevlaragiptssvfalhfteppisaqlla
flrvfcmteeelkehllgdsaidriftlgnsefpvswdnevklwtfledraslllktykt
tieedksvlknhdlsvrakmaiklrlgekeilekavksaavnreyyrqqmeekaplpk

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ictB (B:)
gmgkksrvktqksgtgatatvspkeilnltsellqkcsspapgpgkeweeyvqirtlvek
irkkqkglsvtfdgkredyfpdlmkwasengasvegfemvnfkeegfglratrdikaeel
flwvprkllmtvesaknsvlgplysqdrilqamgnialafhllceraspnsfwqpyiqtl
pseydtplyfeedevrylqstqaihdvfsqykntarqyayfykviqthphanklplkdsf
tyedyrwavssvmtrqnqiptedgsrvtlaliplwdmcnhtnglittgynleddrcecva
lqdfrageqiyifygtrsnaefvihsgfffdnnshdrvkiklgvsksdrlyamkaevlar
agiptssvfalhfteppisaqllaflrvfcmteeelkehllgdsaidriftlgnsefpvs
wdnevklwtfledraslllktykttieedksvlknhdlsvrakmaiklrlgekeilekav
ksaavnreyyrqqmeekaplpkye

    Sequence, based on observed residues (ATOM records):
    >6ictB (B:)
vspkeilnltsellqkcsspapgkeweeyvqirtlvekirkkqkglsvtfdgkredyfpd
lmkwasengasvegfemvnfkeegfglratrdikaeelflwvprkllmtvesaknsvlgp
lysqdrilqamgnialafhllceraspnsfwqpyiqtlpseydtplyfeedevrylqstq
aihdvfsqykntarqyayfykviqthphanklplkdsftyedyrwavssvmtrqnqipte
dgsrvtlaliplwdmcnhtnglittgynleddrcecvalqdfrageqiyifygtrsnaef
vihsgfffdnnshdrvkiklgvsksdrlyamkaevlaragiptssvfalhfteppisaql
laflrvfcmteeelkehllgdsaidriftlgnsefpvswdnevklwtfledraslllkty
kttieedksvlknhdlsvrakmaiklrlgekeilekavksaavnreyyrqqmeekaplpk

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6ictC (C:)
gmgkksrvktqksgtgatatvspkeilnltsellqkcsspapgpgkeweeyvqirtlvek
irkkqkglsvtfdgkredyfpdlmkwasengasvegfemvnfkeegfglratrdikaeel
flwvprkllmtvesaknsvlgplysqdrilqamgnialafhllceraspnsfwqpyiqtl
pseydtplyfeedevrylqstqaihdvfsqykntarqyayfykviqthphanklplkdsf
tyedyrwavssvmtrqnqiptedgsrvtlaliplwdmcnhtnglittgynleddrcecva
lqdfrageqiyifygtrsnaefvihsgfffdnnshdrvkiklgvsksdrlyamkaevlar
agiptssvfalhfteppisaqllaflrvfcmteeelkehllgdsaidriftlgnsefpvs
wdnevklwtfledraslllktykttieedksvlknhdlsvrakmaiklrlgekeilekav
ksaavnreyyrqqmeekaplpkye

    Sequence, based on observed residues (ATOM records):
    >6ictC (C:)
vspkeilnltsellqkcsspapgkeweeyvqirtlvekirkkqkglsvtfdgkredyfpd
lmkwasengasvegfemvnfkeegfglratrdikaeelflwvprkllmtvesaknsvlgp
lysqdrilqamgnialafhllceraspnsfwqpyiqtlpseydtplyfeedevrylqstq
aihdvfsqykntarqyayfykviqthphanklplkdsftyedyrwavssvmtrqnqipte
dgsrvtlaliplwdmcnhtnglittgynleddrcecvalqdfrageqiyifygtrsnaef
vihsgfffdnnshdrvkiklgvsksdrlyamkaevlaragiptssvfalhfteppisaql
laflrvfcmteeelkehllgdsaidriftlgnsefpvswdnevklwtfledraslllkty
kttieedksvlknhdlsvrakmaiklrlgekeilekavksaavnreyyrqqmeekaplp

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6ictD (D:)
gmgkksrvktqksgtgatatvspkeilnltsellqkcsspapgpgkeweeyvqirtlvek
irkkqkglsvtfdgkredyfpdlmkwasengasvegfemvnfkeegfglratrdikaeel
flwvprkllmtvesaknsvlgplysqdrilqamgnialafhllceraspnsfwqpyiqtl
pseydtplyfeedevrylqstqaihdvfsqykntarqyayfykviqthphanklplkdsf
tyedyrwavssvmtrqnqiptedgsrvtlaliplwdmcnhtnglittgynleddrcecva
lqdfrageqiyifygtrsnaefvihsgfffdnnshdrvkiklgvsksdrlyamkaevlar
agiptssvfalhfteppisaqllaflrvfcmteeelkehllgdsaidriftlgnsefpvs
wdnevklwtfledraslllktykttieedksvlknhdlsvrakmaiklrlgekeilekav
ksaavnreyyrqqmeekaplpkye

    Sequence, based on observed residues (ATOM records):
    >6ictD (D:)
vspkeilnltsellqkcsspapgkeweeyvqirtlvekirkkqkglsvtfdgkredyfpd
lmkwasengasvegfemvnfkeegfglratrdikaeelflwvprkllmtvesaknsvlgp
lysqdrilqamgnialafhllceraspnsfwqpyiqtlpseydtplyfeedevrylqstq
aihdvfsqykntarqyayfykviqthphanklplkdsftyedyrwavssvmtrqnqipte
dgsrvtlaliplwdmcnhtnglittgynleddrcecvalqdfrageqiyifygtrsnaef
vihsgfffdnnshdrvkiklgvsksdrlyamkaevlaragiptssvfalhfteppisaql
laflrvfcmteeelkehllgdsaidriftlgnsefpvswdnevklwtfledraslllkty
kttieedksvlknhdlsvrakmaiklrlgekeilekavksaavnreyyrqqmeekaplp

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6ictE (E:)
tlkypiehgivtnwddmekiwhh

    Sequence, based on observed residues (ATOM records):
    >6ictE (E:)
lkypiehgivtnwddmeki

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6ictG (G:)
tlkypiehgivtnwddmekiwhh

    Sequence, based on observed residues (ATOM records):
    >6ictG (G:)
lkypiehgivtnwddmek

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6ictH (H:)
tlkypiehgivtnwddmekiwhh

    Sequence, based on observed residues (ATOM records):
    >6ictH (H:)
lkypiehgivtnwddmeki

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6ictI (I:)
tlkypiehgivtnwddmekiwhh

    Sequence, based on observed residues (ATOM records):
    >6ictI (I:)
kypiehgivtnwddmek