PDB entry 6ic0

View 6ic0 on RCSB PDB site
Description: human pfkfb3 in complex with a n-aryl 6-aminoquinoxaline inhibitor 4
Deposited on 2018-12-01, released 2019-01-23
The last revision was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: PFKFB3
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HAK, POP, FLC, F6P, DMS, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records:
    >6ic0A (A:)
eltqsrvqkiwvpvnsptvivmvglpargktyiskkltrylnwigvptkvfnvgeyrrea
vkqyssynffrpdneeamkvrkqcalaalrdvksylakeggqiavfdatnttrerrhmil
hfakendfkaffiesvcddptvvasnimevkisspdykdcnsaeamddfmkriscyeasy
qpldpdkcdrdlslikvidvgrrflvnrvqdhiqsrivyylmnihvqprtiylcrhgene
hnlqgriggdsglssrgkkfasalskfveeqnlkdlrvwtsqlkstiqtaealrlpyeqw
kalneidagvceeltyeeirdtypeeyalreqdkyyyryptgesyqdlvqrlepvimele
rqenvlvichqavlrcllayfldksaeempylkcplhtvlkltpvaygcrvesiylnves
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