PDB entry 6ib5

View 6ib5 on RCSB PDB site
Description: mutant of flavin-dependent tryptophan halogenase thal with altered regioselectivity (thal-rebh5)
Deposited on 2018-11-29, released 2018-12-26
The last revision was dated 2019-02-27, with a file datestamp of 2019-02-22.
Experiment type: XRAY
Resolution: 2.12 Å
R-factor: N/A
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tryptophan 6-halogenase
    Species: Streptomyces albogriseolus [TaxId:1887]
    Gene: thal, thdH
    Database cross-references and differences (RAF-indexed):
    • Uniprot A1E280 (4-End)
      • engineered mutation (54)
      • engineered mutation (84)
      • engineered mutation (362)
      • engineered mutation (471-472)
  • Chain 'B':
    Compound: Tryptophan 6-halogenase
    Species: Streptomyces albogriseolus [TaxId:1887]
    Gene: thal, thdH
    Database cross-references and differences (RAF-indexed):
    • Uniprot A1E280 (4-End)
      • expression tag (3)
      • engineered mutation (54)
      • engineered mutation (84)
      • engineered mutation (362)
      • engineered mutation (471-472)
  • Heterogens: PO4, GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ib5A (A:)
gamgdnriktvvilgggtagwmtaaylgkalqntvkivvleaptiprigvgeatipnlqr
affdylgipeeewmrecnasykmaikfinwrtpgegspdprtlddghtdtfhhpfgllps
adqiplshywaakrlqgetdenfdeacfadtaimnakkaprfldmrratnyawhfdaskv
aaflrnfavtkqavehvedemtevltdergfitalrtksgrilqgdlfvdcsgfrgllin
kameepfidmsdhllcnsavatavphddekngvepytssiameagwtwkipmlgrfgsgh
vysdhfatqdeatlafsklwgldpdntefnhvrfrvgrnrrawvrncvsvglascfvepl
estgiyfiyaaihmlakhfpdktfdkvlvdrfnreieemfddtrdflqahyyfsprvdtp
fwrankelkladsikdkvetyraglpvnlpvtdegtyygnfeaefrnfwtnsnyycifag
lglmprnplpalaykpqsiaeaellfadvkrkgdtlveslpstydllrqlhgas

    Sequence, based on observed residues (ATOM records):
    >6ib5A (A:)
dnriktvvilgggtagwmtaaylgkalqntvkivvleaptiprigvgeatipnlqraffd
ylgipeeewmrecnasykmaikfinwrtpgegspdprtlddghtdtfhhpfgllpsadqi
plshywaakrlqgetdenfdeacfadtaimnakkaprfldmrratnyawhfdaskvaafl
rnfavtkqavehvedemtevltdergfitalrtksgrilqgdlfvdcsgfrgllinkame
epfidmsdhllcnsavatavphddekngvepytssiameagwtwkipmlgrfgsghvysd
hfatqdeatlafsklwgldpdntefnhvrfrvgrnrrawvrncvsvglascfveplestg
iyfiyaaihmlakhfpdktfdkvlvdrfnreieemfddtrdflqahyyfsprvdtpfwra
nkelkladsikdkvetyraglpvnlpvtdegtynfeaefrnfwtnsnyycifaglglmpr
nplpalaykpqsiaeaellfadvkrkgdtlveslpstydllrqlhg

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ib5B (B:)
gamgdnriktvvilgggtagwmtaaylgkalqntvkivvleaptiprigvgeatipnlqr
affdylgipeeewmrecnasykmaikfinwrtpgegspdprtlddghtdtfhhpfgllps
adqiplshywaakrlqgetdenfdeacfadtaimnakkaprfldmrratnyawhfdaskv
aaflrnfavtkqavehvedemtevltdergfitalrtksgrilqgdlfvdcsgfrgllin
kameepfidmsdhllcnsavatavphddekngvepytssiameagwtwkipmlgrfgsgh
vysdhfatqdeatlafsklwgldpdntefnhvrfrvgrnrrawvrncvsvglascfvepl
estgiyfiyaaihmlakhfpdktfdkvlvdrfnreieemfddtrdflqahyyfsprvdtp
fwrankelkladsikdkvetyraglpvnlpvtdegtyygnfeaefrnfwtnsnyycifag
lglmprnplpalaykpqsiaeaellfadvkrkgdtlveslpstydllrqlhgas

    Sequence, based on observed residues (ATOM records):
    >6ib5B (B:)
gdnriktvvilgggtagwmtaaylgkalqntvkivvleaptiprigvgeatipnlqraff
dylgipeeewmrecnasykmaikfinwrtpgegspdprtlddghtdtfhhpfgllpsadq
iplshywaakrlqgetdenfdeacfadtaimnakkaprfldmrratnyawhfdaskvaaf
lrnfavtkqavehvedemtevltdergfitalrtksgrilqgdlfvdcsgfrgllinkam
eepfidmsdhllcnsavatavphddekngvepytssiameagwtwkipmlgrfgsghvys
dhfatqdeatlafsklwgldpdntefnhvrfrvgrnrrawvrncvsvglascfveplest
giyfiyaaihmlakhfpdktfdkvlvdrfnreieemfddtrdflqahyyfsprvdtpfwr
ankelkladsikdkvetyraglpvnlpvtdegnfeaefrnfwtnsnyycifaglglmprn
plpalaykpqsiaeaellfadvkrkgdtlveslpstydllrqlh