PDB entry 6iap

View 6iap on RCSB PDB site
Description: structure of human nkp46 in complex with antibody nkp46-1 and nkp46-4
Deposited on 2018-11-27, released 2019-06-12
The last revision was dated 2019-06-26, with a file datestamp of 2019-06-21.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: natural cytotoxicity triggering receptor 1
    Species: Homo sapiens [TaxId:9606]
    Gene: NCR1, LY94
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Fab NKp46-4 light chain
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6IAP (0-210)
  • Chain 'E':
    Compound: Fab NKp46-4 heavy chain
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6IAP (0-216)
  • Chain 'H':
    Compound: Fab NKp46-1 heavy chain
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6IAP (0-219)
  • Chain 'L':
    Compound: Fab NKp46-1 light chain
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6IAP (0-210)
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records:
    >6iapA (A:)
    tlpkpfiwaephfmvpkekqvticcqgnygaveyqlhfegslfavdrpkpperinkvkfy
    ipdmnsrmagqysciyrvgelwsepsnlldlvvtemydtptlsvhpgpevisgekvtfyc
    rldtatsmflllkegrsshvqrgygkvqaefplgpvttahrgtyrcfgsynnhawsfpse
    pv
    

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records:
    >6iapD (D:)
    diqmtqspsslsasvgdrvtitcraseniysnlawfqqkpgkapkllvyaatnladgvps
    rfsgsgsgtdytltisslqpedfatyycqhfwgtprtfgggtkveikrtvaapsvfifpp
    sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
    lskadyekhkvyacevthqglsspvtksfnr
    

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records:
    >6iapE (E:)
    qvqlvqsgaevkkpgasvkvsckasgytftsftmhwvrqapgqglewigyinpssgytey
    nqkfkdrvtitadkststaymelsslrsedtavyycvrgssrgfdywgqgtlvtvssast
    kgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
    slssvvtvpssslgtqtyicnvnhkpsntkvdkrvep
    

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records:
    >6iapH (H:)
    qvqlvqsgaevkkpgssvkvsckasgytfsdyvinwvrqapgqglewmgeiypgsgtnyy
    nekfkakatitadkststaymelsslrsedtavyycarrgryglyamdywgqgttvtvss
    astkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
    glyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvep
    

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records:
    >6iapL (L:)
    diqmtqspsslsasvgdrvtitcrasqdisnylnwyqqkpgkapklliyytsrlhsgvps
    rfsgsgsgtdftftisslqpediatyfcqqgntrpwtfgggtkveikrtvaapsvfifpp
    sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
    lskadyekhkvyacevthqglsspvtksfnr