SCOPe 2.08: Structural Classification of Proteins

PDB entry 6iao

View 6iao on RCSB PDB site
Description: Structure of Cytochrome P450 BM3 M11 mutant in complex with DTT at resolution 2.16A
Class: oxidoreductase
Keywords: Cytochrome P450 BM3, mutant M11, DTT, OXIDOREDUCTASE
Deposited on 2018-11-27, released 2019-06-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-06-05, with a file datestamp of 2019-05-30.
Experiment type: XRAY
Resolution: 2.16 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Bifunctional cytochrome P450/NADPH--P450 reductase
Species: Bacillus megaterium [TaxId:1404]
Gene: cyp102A1, cyp102, BG04_163
Database cross-references and differences (RAF-indexed):
- Uniprot P14779
  - engineered mutation (81)
  - engineered mutation (98)
  - engineered mutation (115)
  - engineered mutation (121)
  - engineered mutation (177)
  - engineered mutation (222)
  - engineered mutation (232)
  - engineered mutation (301)
  - engineered mutation (319)
  - engineered mutation (449)
Domains in SCOPe 2.08: d6iaoa_
Chain 'B':
Compound: Bifunctional cytochrome P450/NADPH--P450 reductase
Species: Bacillus megaterium [TaxId:1404]
Gene: cyp102A1, cyp102, BG04_163
Database cross-references and differences (RAF-indexed):
- Uniprot P14779
  - engineered mutation (81)
  - engineered mutation (98)
  - engineered mutation (115)
  - engineered mutation (121)
  - engineered mutation (177)
  - engineered mutation (222)
  - engineered mutation (232)
  - engineered mutation (301)
  - engineered mutation (319)
  - engineered mutation (449)
Domains in SCOPe 2.08: d6iaob_
Chain 'C':
Compound: Bifunctional cytochrome P450/NADPH--P450 reductase
Species: Bacillus megaterium [TaxId:1404]
Gene: cyp102A1, cyp102, BG04_163
Database cross-references and differences (RAF-indexed):
- Uniprot P14779 (34-End)
  - expression tag (29-33)
  - engineered mutation (81)
  - engineered mutation (98)
  - engineered mutation (115)
  - engineered mutation (121)
  - engineered mutation (177)
  - engineered mutation (222)
  - engineered mutation (301)
  - engineered mutation (319)
  - engineered mutation (449)
Domains in SCOPe 2.08: d6iaoc1, d6iaoc2
Chain 'D':
Compound: Bifunctional cytochrome P450/NADPH--P450 reductase
Species: Bacillus megaterium [TaxId:1404]
Gene: cyp102A1, cyp102, BG04_163
Database cross-references and differences (RAF-indexed):
- Uniprot P14779
  - engineered mutation (81)
  - engineered mutation (98)
  - engineered mutation (115)
  - engineered mutation (121)
  - engineered mutation (177)
  - engineered mutation (222)
  - engineered mutation (232)
  - engineered mutation (301)
  - engineered mutation (319)
  - engineered mutation (449)
Domains in SCOPe 2.08: d6iaod_
Heterogens: HEM, DTT, CL, GOL, PEG, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>6iaoA (A:)
mgsshhhhhhssglvprgshmasmtggqqmgrgsmtikempqpktfgelknlpllntdkp
vqalmkiadelgeifkfeapglvtrylssqrlikeacdgsrfdknlsqalkfvrdiagdg
lvtswtheknwkkahnillpsfsqqamkgyhammvdiavqlvqkwerlnadehievpgdm
trltldtiglcgfnyrfnsfyrdqphpfitsmvraldeamnkqqranpddpacdenkrqf
qedikvmndlvdkiiadrkasgeqsddllthmlngkdpetgeplddeniryqiitfliag
hvttsgllsfalyflvknpyvlqkaaeeaarvlvdpvpsykqvkqlkyvgmvlnealrlw
ptapafslyakedtvlggeyplekgdelmvlipqlhrdktiwgddveefrperfenpsai
pqhafkpfgngqracigqqfalheatlvlsmmlkhfdfedhtnyeldiketltlkpegfv
vkakskkiplggipspsteqsakkvrk

Sequence, based on observed residues (ATOM records): (download)

>6iaoA (A:)
kempqpktfgelknlpllntdkpvqalmkiadelgeifkfeapglvtrylssqrlikeac
dgsrfdknlsqalkfvrdiagdglvtswtheknwkkahnillpsfsqqamkgyhammvdi
avqlvqkwerlnadehievpgdmtrltldtiglcgfnyrfnsfyrdqphpfitsmvrald
eamnkqqranpddpacdenkrqfqedikvmndlvdkiiadrkasgeqsddllthmlngkd
petgeplddeniryqiitfliaghvttsgllsfalyflvknpyvlqkaaeeaarvlvdpv
psykqvkqlkyvgmvlnealrlwptapafslyakedtvlggeyplekgdelmvlipqlhr
dktiwgddveefrperfenpsaipqhafkpfgngqracigqqfalheatlvlsmmlkhfd
fedhtnyeldiketltlkpegfvvkakskkiplgg

Chain 'B':
Sequence, based on SEQRES records: (download)

>6iaoB (B:)
mgsshhhhhhssglvprgshmasmtggqqmgrgsmtikempqpktfgelknlpllntdkp
vqalmkiadelgeifkfeapglvtrylssqrlikeacdgsrfdknlsqalkfvrdiagdg
lvtswtheknwkkahnillpsfsqqamkgyhammvdiavqlvqkwerlnadehievpgdm
trltldtiglcgfnyrfnsfyrdqphpfitsmvraldeamnkqqranpddpacdenkrqf
qedikvmndlvdkiiadrkasgeqsddllthmlngkdpetgeplddeniryqiitfliag
hvttsgllsfalyflvknpyvlqkaaeeaarvlvdpvpsykqvkqlkyvgmvlnealrlw
ptapafslyakedtvlggeyplekgdelmvlipqlhrdktiwgddveefrperfenpsai
pqhafkpfgngqracigqqfalheatlvlsmmlkhfdfedhtnyeldiketltlkpegfv
vkakskkiplggipspsteqsakkvrk

Sequence, based on observed residues (ATOM records): (download)

>6iaoB (B:)
mpqpktfgelknlpllntdkpvqalmkiadelgeifkfeapglvtrylssqrlikeacdg
srfdknlsqalkfvrdiagdglvtswtheknwkkahnillpsfsqqamkgyhammvdiav
qlvqkwerlnadehievpgdmtrltldtiglcgfnyrfnsfyrdqphpfitsmvraldea
mnkqqranpddpacdenkrqfqedikvmndlvdkiiadrkasgeqsddllthmlngkdpe
tgeplddeniryqiitfliaghvttsgllsfalyflvknpyvlqkaaeeaarvlvdpvps
ykqvkqlkyvgmvlnealrlwptapafslyakedtvlggeyplekgdelmvlipqlhrdk
tiwgddveefrperfenpsaipqhafkpfgngqracigqqfalheatlvlsmmlkhfdfe
dhtnyeldiketltlkpegfvvkakskkiplg

Chain 'C':
Sequence, based on SEQRES records: (download)

>6iaoC (C:)
mgsshhhhhhssglvprgshmasmtggqqmgrgsmtikempqpktfgelknlpllntdkp
vqalmkiadelgeifkfeapglvtrylssqrlikeacdgsrfdknlsqalkfvrdiagdg
lvtswtheknwkkahnillpsfsqqamkgyhammvdiavqlvqkwerlnadehievpgdm
trltldtiglcgfnyrfnsfyrdqphpfitsmvraldeamnkqqranpddpacdenkrqf
qedikvmndlvdkiiadrkasgeqsddllthmlngkdpetgeplddeniryqiitfliag
hvttsgllsfalyflvknpyvlqkaaeeaarvlvdpvpsykqvkqlkyvgmvlnealrlw
ptapafslyakedtvlggeyplekgdelmvlipqlhrdktiwgddveefrperfenpsai
pqhafkpfgngqracigqqfalheatlvlsmmlkhfdfedhtnyeldiketltlkpegfv
vkakskkiplggipspsteqsakkvrk

Sequence, based on observed residues (ATOM records): (download)

>6iaoC (C:)
mgrgsmtikempqpktfgelknlpllntdkpvqalmkiadelgeifkfeapglvtrylss
qrlikeacdgsrfdknlsqalkfvrdiagdglvtswtheknwkkahnillpsfsqqamkg
yhammvdiavqlvqkwerlnadehievpgdmtrltldtiglcgfnyrfnsfyrdqphpfi
tsmvraldeamnkqqrafqedikvmndlvdkiiadrkasgeqsddllthmlngkdpetge
plddeniryqiitfliaghvttsgllsfalyflvknpyvlqkaaeeaarvlvdpvpsykq
vkqlkyvgmvlnealrlwptapafslyakedtvlggeyplekgdelmvlipqlhrdktiw
gddveefrperfenpsaipqhafkpfgngqracigqqfalheatlvlsmmlkhfdfedht
nyeldiketltlkpegfvvkakskkiplgg

Chain 'D':
Sequence, based on SEQRES records: (download)

>6iaoD (D:)
mgsshhhhhhssglvprgshmasmtggqqmgrgsmtikempqpktfgelknlpllntdkp
vqalmkiadelgeifkfeapglvtrylssqrlikeacdgsrfdknlsqalkfvrdiagdg
lvtswtheknwkkahnillpsfsqqamkgyhammvdiavqlvqkwerlnadehievpgdm
trltldtiglcgfnyrfnsfyrdqphpfitsmvraldeamnkqqranpddpacdenkrqf
qedikvmndlvdkiiadrkasgeqsddllthmlngkdpetgeplddeniryqiitfliag
hvttsgllsfalyflvknpyvlqkaaeeaarvlvdpvpsykqvkqlkyvgmvlnealrlw
ptapafslyakedtvlggeyplekgdelmvlipqlhrdktiwgddveefrperfenpsai
pqhafkpfgngqracigqqfalheatlvlsmmlkhfdfedhtnyeldiketltlkpegfv
vkakskkiplggipspsteqsakkvrk

Sequence, based on observed residues (ATOM records): (download)

>6iaoD (D:)
empqpktfgelknlpllntdkpvqalmkiadelgeifkfeapglvtrylssqrlikeacd
gsrfdknlsqalkfvrdiagdglvtswtheknwkkahnillpsfsqqamkgyhammvdia
vqlvqkwerlnadehievpgdmtrltldtiglcgfnyrfnsfyrdqphpfitsmvralde
amnkqddpacdenkrqfqedikvmndlvdkiiadrkasgeqsddllthmlngkdpetgep
lddeniryqiitfliaghvttsgllsfalyflvknpyvlqkaaeeaarvlvdpvpsykqv
kqlkyvgmvlnealrlwptapafslyakedtvlggeyplekgdelmvlipqlhrdktiwg
ddveefrperfenpsaipqhafkpfgngqracigqqfalheatlvlsmmlkhfdfedhtn
yeldiketltlkpegfvvkakskkiplggi