PDB entry 6i8z

View 6i8z on RCSB PDB site
Description: Crystal structure of PTK2 in complex with BI-4464.
Class: transferase
Keywords: Inhibitor, Protein kinase, TRANSFERASE
Deposited on 2018-11-21, released 2019-02-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-03-27, with a file datestamp of 2019-03-22.
Experiment type: XRAY
Resolution: 1.99 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Focal adhesion kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PTK2, FAK, FAK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6i8za_
  • Heterogens: H82, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6i8zA (A:)
gsstrdyeiqrerielgrcigegqfgdvhqgiymspenpalavaiktcknctsdsvrekf
lqealtmrqfdhphivkligvitenpvwiimelctlgelrsflqvrkysldlaslilyay
qlstalayleskrfvhrdiaarnvlvssndcvklgdfglsrymedstyykaskgklpikw
mapesinfrrftsasdvwmfgvcmweilmhgvkpfqgvknndvigriengerlpmppncp
ptlyslmtkcwaydpsrrprftelkaqlstileeekaqqee

    Sequence, based on observed residues (ATOM records): (download) 
    >6i8zA (A:)
dyeiqrerielgrcigegqfgdvhqgiymspenpalavaiktcknctsdsvrekflqeal
tmrqfdhphivkligvitenpvwiimelctlgelrsflqvrkysldlaslilyayqlsta
layleskrfvhrdiaarnvlvssndcvklgdfglsrlpikwmapesinfrrftsasdvwm
fgvcmweilmhgvkpfqgvknndvigriengerlpmppncpptlyslmtkcwaydpsrrp
rftelkaqlstileeekaqqe