PDB entry 6i81

View 6i81 on RCSB PDB site
Description: Crystal Structure of the second bromodomain of BRD2 in complex with RT56
Class: transcription
Keywords: BET, Bromodomain, RT56, inhibitor, Structural Genomics, Structural Genomics Consortium, SGC, TRANSCRIPTION
Deposited on 2018-11-19, released 2019-11-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-11-27, with a file datestamp of 2019-11-22.
Experiment type: XRAY
Resolution: 1.74 Å
R-factor: N/A
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Bromodomain-containing protein 2
  Species: Homo sapiens [TaxId:9606]
  Gene: BRD2, KIAA9001, RING3
  Database cross-references and differences (RAF-indexed):
  • Uniprot P25440 (2-109)
    • expression tag (0-1)
  Domains in SCOPe 2.08: d6i81a1, d6i81a2
• Heterogens: MES, EDO, H7E, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >6i81A (A:)
  smeqlkhcngilkellskkhaayawpfykpvdasalglhdyhdiikhpmdlstvkrkmen
  rdyrdaqefaadvrlmfsncykynppdhdvvamarklqdvfefryakmpd