PDB entry 6i7p

View 6i7p on RCSB PDB site
Description: crystal structure of the full-length zika virus ns5 protein (human isolate z1106033)
Deposited on 2018-11-16, released 2019-04-24
The last revision was dated 2019-05-08, with a file datestamp of 2019-05-03.
Experiment type: XRAY
Resolution: 3.98 Å
R-factor: N/A
AEROSPACI score: 0.05 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ns5
    Species: Zika virus [TaxId:64320]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: ns5
    Species: Zika virus [TaxId:64320]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: ns5
    Species: Zika virus [TaxId:64320]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: ns5
    Species: Zika virus [TaxId:64320]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: ns5
    Species: Zika virus [TaxId:64320]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: ns5
    Species: Zika virus [TaxId:64320]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: SAH, PO4, ZN

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6i7pA (A:)
mgggtgetlgekwkarlnqmsalefysykksgitevcreearralkdgvatgghavsrgs
aklrwlvergylqpygkvidlgcgrggwsyyaatirkvqevkgytkggpgheepvlvqsy
gwnivrlksgvdvfhmaaepcdtllcdigesssspeveeartlrvlsmvgdwlekrpgaf
cikvlcpytstmmetlerlqrryggglvrvplsrnsthemywvsgaksntiksvsttsql
llgrmdgprrpvkyeedvnlgsgtravvscaeapnmkiignrierirsehaetwffdenh
pyrtwayhgsyeaptqgsasslingvvrllskpwdvvtgvtgiamtdttpygqqrvfkek
vdtrvpdpqegtrqvmsmvsswlwkelgkhkrprvctkeefinkvrsnaalgaifeeeke
wktaveavndprfwalvdkerehhlrgecqscvynmmgkrekkqgefgkakgsraiwymw
lgarflefealgflnedhwmgrensgggveglglqrlgyvleemsripggrmyaddtagw
dtrisrfdlenealitnqmekghralalaiikytyqnkvvkvlrpaekgktvmdiisrqd
qrgsgqvvtyalntftnlvvqlirnmeaeevlemqdlwllrrsekvtnwlqsngwdrlkr
mavsgddcvvkpiddrfahalrflndmgkvrkdtqewkpstgwdnweevpfcshhfnklh
lkdgrsivvpcrhqdeligrarvspgagwsiretaclaksyaqmwqllyfhrrdlrlman
aicssvpvdwvptgrttwsihgkgewmttedmlvvwnrvwieendhmedktpvtkwtdip
ylgkredlwcgslighrprttwaenikntvnmvrriigdeekymdylstqvrylgeegst
pgvlgssshhhhhh

    Sequence, based on observed residues (ATOM records):
    >6i7pA (A:)
etlgekwkarlnqmsalefysykksgitevcreearralkdgvatgghavsrgsaklrwl
vergylqpygkvidlgcgrggwsyyaatirkvqevkgytkggpgheepvlvqsygwnivr
lksgvdvfhmaaepcdtllcdigesssspeveeartlrvlsmvgdwlekrpgafcikvlc
pytstmmetlerlqrryggglvrvplsrnsthemywvsgaksntiksvsttsqlllgrmd
gprrpvkyeedvnlgsgtravvscaeapnmkiignrierirsehaetwffdenhpyrtwa
yhgsyeaptqgsasslingvvrllskpwdvvtgvtgiamtdttpygqqrvfkekvdtrvp
dpqegtrqvmsmvsswlwkelgkhkrprvctkeefinkvrsnaalgaifeeekewktave
avndprfwalvdkerehhlrgecqscvynmmgkrekkqgefgkakgsraiwymwlgarfl
efealgflnedhwmgrensgggveglglqrlgyvleemsripggrmyaddtagwdtrisr
fdlenealitnqmekghralalaiikytyqnkvvkvlrpaekgktvmdiisrqdqrgsgq
vvtyalntftnlvvqlirnmeaeevlemqdlwllrrsekvtnwlqsngwdrlkrmavsgd
dcvvkpiddrfahalrflndmgkvrkdtqewkpstgwdnweevpfcshhfnklhlkdgrs
ivvpcrhqdeligrarvspgagwsiretaclaksyaqmwqllyfhrrdlrlmanaicssv
pvdwvptgrttwsihgkgewmttedmlvvwnrvwieendhmedktpvtkwtdipylgkre
dlwcgslighrprttwaenikntvnmvrriigdeekymdylst

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6i7pB (B:)
mgggtgetlgekwkarlnqmsalefysykksgitevcreearralkdgvatgghavsrgs
aklrwlvergylqpygkvidlgcgrggwsyyaatirkvqevkgytkggpgheepvlvqsy
gwnivrlksgvdvfhmaaepcdtllcdigesssspeveeartlrvlsmvgdwlekrpgaf
cikvlcpytstmmetlerlqrryggglvrvplsrnsthemywvsgaksntiksvsttsql
llgrmdgprrpvkyeedvnlgsgtravvscaeapnmkiignrierirsehaetwffdenh
pyrtwayhgsyeaptqgsasslingvvrllskpwdvvtgvtgiamtdttpygqqrvfkek
vdtrvpdpqegtrqvmsmvsswlwkelgkhkrprvctkeefinkvrsnaalgaifeeeke
wktaveavndprfwalvdkerehhlrgecqscvynmmgkrekkqgefgkakgsraiwymw
lgarflefealgflnedhwmgrensgggveglglqrlgyvleemsripggrmyaddtagw
dtrisrfdlenealitnqmekghralalaiikytyqnkvvkvlrpaekgktvmdiisrqd
qrgsgqvvtyalntftnlvvqlirnmeaeevlemqdlwllrrsekvtnwlqsngwdrlkr
mavsgddcvvkpiddrfahalrflndmgkvrkdtqewkpstgwdnweevpfcshhfnklh
lkdgrsivvpcrhqdeligrarvspgagwsiretaclaksyaqmwqllyfhrrdlrlman
aicssvpvdwvptgrttwsihgkgewmttedmlvvwnrvwieendhmedktpvtkwtdip
ylgkredlwcgslighrprttwaenikntvnmvrriigdeekymdylstqvrylgeegst
pgvlgssshhhhhh

    Sequence, based on observed residues (ATOM records):
    >6i7pB (B:)
etlgekwkarlnqmsalefysykksgitevcreearralkdgvatgghavsrgsaklrwl
vergylqpygkvidlgcgrggwsyyaatirkvqevkgytkggpgheepvlvqsygwnivr
lksgvdvfhmaaepcdtllcdigesssspeveeartlrvlsmvgdwlekrpgafcikvlc
pytstmmetlerlqrryggglvrvplsrnsthemywvsgaksntiksvsttsqlllgrmd
gprrpvkyeedvnlgsgtravvscaeapnmkiignrierirsehaetwffdenhpyrtwa
yhgsyeaptqgsasslingvvrllskpwdvvtgvtgiamtdttpygqqrvfkekvdtrvp
dpqegtrqvmsmvsswlwkelgkhkrprvctkeefinkvrsnaalgaifeeekewktave
avndprfwalvdkerehhlrgecqscvynmmgkrekkqgefgkakgsraiwymwlgarfl
efealgflnedhwmgrensgggveglglqrlgyvleemsripggrmyaddtagwdtrisr
fdlenealitnqmekghralalaiikytyqnkvvkvlrpaekgktvmdiisrqdqrgsgq
vvtyalntftnlvvqlirnmeaeevlemqdlwllrrsekvtnwlqsngwdrlkrmavsgd
dcvvkpiddrfahalrflndmgkvrkdtqewkpstgwdnweevpfcshhfnklhlkdgrs
ivvpcrhqdeligrarvspgagwsiretaclaksyaqmwqllyfhrrdlrlmanaicssv
pvdwvptgrttwsihgkgewmttedmlvvwnrvwieendhmedktpvtkwtdipylgkre
dlwcgslighrprttwaenikntvnmvrriigdeekymdyls

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6i7pC (C:)
mgggtgetlgekwkarlnqmsalefysykksgitevcreearralkdgvatgghavsrgs
aklrwlvergylqpygkvidlgcgrggwsyyaatirkvqevkgytkggpgheepvlvqsy
gwnivrlksgvdvfhmaaepcdtllcdigesssspeveeartlrvlsmvgdwlekrpgaf
cikvlcpytstmmetlerlqrryggglvrvplsrnsthemywvsgaksntiksvsttsql
llgrmdgprrpvkyeedvnlgsgtravvscaeapnmkiignrierirsehaetwffdenh
pyrtwayhgsyeaptqgsasslingvvrllskpwdvvtgvtgiamtdttpygqqrvfkek
vdtrvpdpqegtrqvmsmvsswlwkelgkhkrprvctkeefinkvrsnaalgaifeeeke
wktaveavndprfwalvdkerehhlrgecqscvynmmgkrekkqgefgkakgsraiwymw
lgarflefealgflnedhwmgrensgggveglglqrlgyvleemsripggrmyaddtagw
dtrisrfdlenealitnqmekghralalaiikytyqnkvvkvlrpaekgktvmdiisrqd
qrgsgqvvtyalntftnlvvqlirnmeaeevlemqdlwllrrsekvtnwlqsngwdrlkr
mavsgddcvvkpiddrfahalrflndmgkvrkdtqewkpstgwdnweevpfcshhfnklh
lkdgrsivvpcrhqdeligrarvspgagwsiretaclaksyaqmwqllyfhrrdlrlman
aicssvpvdwvptgrttwsihgkgewmttedmlvvwnrvwieendhmedktpvtkwtdip
ylgkredlwcgslighrprttwaenikntvnmvrriigdeekymdylstqvrylgeegst
pgvlgssshhhhhh

    Sequence, based on observed residues (ATOM records):
    >6i7pC (C:)
etlgekwkarlnqmsalefysykksgitevcreearralkdgvatgghavsrgsaklrwl
vergylqpygkvidlgcgrggwsyyaatirkvqevkgytkggpgheepvlvqsygwnivr
lksgvdvfhmaaepcdtllcdigesssspeveeartlrvlsmvgdwlekrpgafcikvlc
pytstmmetlerlqrryggglvrvplsrnsthemywvsgaksntiksvsttsqlllgrmd
gprrpvkyeedvnlgsgtravvscaeapnmkiignrierirsehaetwffdenhpyrtwa
yhgsyeaptqgsasslingvvrllskpwdvvtgvtgiamtdttpygqqrvfkekvdtrvp
dpqegtrqvmsmvsswlwkelgkhkrprvctkeefinkvrsnaalgaifeeekewktave
avndprfwalvdkerehhlrgecqscvynmmgkrekkqgefgkakgsraiwymwlgarfl
efealgflnedhwmgrensgggveglglqrlgyvleemsripggrmyaddtagwdtrisr
fdlenealitnqmekghralalaiikytyqnkvvkvlrpaekgktvmdiisrqdqrgsgq
vvtyalntftnlvvqlirnmeaeevlemqdlwllrrsekvtnwlqsngwdrlkrmavsgd
dcvvkpiddrfahalrflndmgkvrkdtqewkpstgwdnweevpfcshhfnklhlkdgrs
ivvpcrhqdeligrarvspgagwsiretaclaksyaqmwqllyfhrrdlrlmanaicssv
pvdwvptgrttwsihgkgewmttedmlvvwnrvwieendhmedktpvtkwtdipylgkre
dlwcgslighrprttwaenikntvnmvrriigdeekymdylst

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6i7pD (D:)
mgggtgetlgekwkarlnqmsalefysykksgitevcreearralkdgvatgghavsrgs
aklrwlvergylqpygkvidlgcgrggwsyyaatirkvqevkgytkggpgheepvlvqsy
gwnivrlksgvdvfhmaaepcdtllcdigesssspeveeartlrvlsmvgdwlekrpgaf
cikvlcpytstmmetlerlqrryggglvrvplsrnsthemywvsgaksntiksvsttsql
llgrmdgprrpvkyeedvnlgsgtravvscaeapnmkiignrierirsehaetwffdenh
pyrtwayhgsyeaptqgsasslingvvrllskpwdvvtgvtgiamtdttpygqqrvfkek
vdtrvpdpqegtrqvmsmvsswlwkelgkhkrprvctkeefinkvrsnaalgaifeeeke
wktaveavndprfwalvdkerehhlrgecqscvynmmgkrekkqgefgkakgsraiwymw
lgarflefealgflnedhwmgrensgggveglglqrlgyvleemsripggrmyaddtagw
dtrisrfdlenealitnqmekghralalaiikytyqnkvvkvlrpaekgktvmdiisrqd
qrgsgqvvtyalntftnlvvqlirnmeaeevlemqdlwllrrsekvtnwlqsngwdrlkr
mavsgddcvvkpiddrfahalrflndmgkvrkdtqewkpstgwdnweevpfcshhfnklh
lkdgrsivvpcrhqdeligrarvspgagwsiretaclaksyaqmwqllyfhrrdlrlman
aicssvpvdwvptgrttwsihgkgewmttedmlvvwnrvwieendhmedktpvtkwtdip
ylgkredlwcgslighrprttwaenikntvnmvrriigdeekymdylstqvrylgeegst
pgvlgssshhhhhh

    Sequence, based on observed residues (ATOM records):
    >6i7pD (D:)
etlgekwkarlnqmsalefysykksgitevcreearralkdgvatgghavsrgsaklrwl
vergylqpygkvidlgcgrggwsyyaatirkvqevkgytkggpgheepvlvqsygwnivr
lksgvdvfhmaaepcdtllcdigesssspeveeartlrvlsmvgdwlekrpgafcikvlc
pytstmmetlerlqrryggglvrvplsrnsthemywvsgaksntiksvsttsqlllgrmd
gprrpvkyeedvnlgsgtravvscaeapnmkiignrierirsehaetwffdenhpyrtwa
yhgsyeaptqgsasslingvvrllskpwdvvtgvtgiamtdttpygqqrvfkekvdtrvp
dpqegtrqvmsmvsswlwkelgkhkrprvctkeefinkvrsnaalgaifeeekewktave
avndprfwalvdkerehhlrgecqscvynmmgkrekkqgefgkakgsraiwymwlgarfl
efealgflnedhwmgrensgggveglglqrlgyvleemsripggrmyaddtagwdtrisr
fdlenealitnqmekghralalaiikytyqnkvvkvlrpaekgktvmdiisrqdqrgsgq
vvtyalntftnlvvqlirnmeaeevlemqdlwllrrsekvtnwlqsngwdrlkrmavsgd
dcvvkpiddrfahalrflndmgkvrkdtqewkpstgwdnweevpfcshhfnklhlkdgrs
ivvpcrhqdeligrarvspgagwsiretaclaksyaqmwqllyfhrrdlrlmanaicssv
pvdwvptgrttwsihgkgewmttedmlvvwnrvwieendhmedktpvtkwtdipylgkre
dlwcgslighrprttwaenikntvnmvrriigdeekymdylst

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6i7pE (E:)
mgggtgetlgekwkarlnqmsalefysykksgitevcreearralkdgvatgghavsrgs
aklrwlvergylqpygkvidlgcgrggwsyyaatirkvqevkgytkggpgheepvlvqsy
gwnivrlksgvdvfhmaaepcdtllcdigesssspeveeartlrvlsmvgdwlekrpgaf
cikvlcpytstmmetlerlqrryggglvrvplsrnsthemywvsgaksntiksvsttsql
llgrmdgprrpvkyeedvnlgsgtravvscaeapnmkiignrierirsehaetwffdenh
pyrtwayhgsyeaptqgsasslingvvrllskpwdvvtgvtgiamtdttpygqqrvfkek
vdtrvpdpqegtrqvmsmvsswlwkelgkhkrprvctkeefinkvrsnaalgaifeeeke
wktaveavndprfwalvdkerehhlrgecqscvynmmgkrekkqgefgkakgsraiwymw
lgarflefealgflnedhwmgrensgggveglglqrlgyvleemsripggrmyaddtagw
dtrisrfdlenealitnqmekghralalaiikytyqnkvvkvlrpaekgktvmdiisrqd
qrgsgqvvtyalntftnlvvqlirnmeaeevlemqdlwllrrsekvtnwlqsngwdrlkr
mavsgddcvvkpiddrfahalrflndmgkvrkdtqewkpstgwdnweevpfcshhfnklh
lkdgrsivvpcrhqdeligrarvspgagwsiretaclaksyaqmwqllyfhrrdlrlman
aicssvpvdwvptgrttwsihgkgewmttedmlvvwnrvwieendhmedktpvtkwtdip
ylgkredlwcgslighrprttwaenikntvnmvrriigdeekymdylstqvrylgeegst
pgvlgssshhhhhh

    Sequence, based on observed residues (ATOM records):
    >6i7pE (E:)
etlgekwkarlnqmsalefysykksgitevcreearralkdgvatgghavsrgsaklrwl
vergylqpygkvidlgcgrggwsyyaatirkvqevkgytkggpgheepvlvqsygwnivr
lksgvdvfhmaaepcdtllcdigesssspeveeartlrvlsmvgdwlekrpgafcikvlc
pytstmmetlerlqrryggglvrvplsrnsthemywvsgaksntiksvsttsqlllgrmd
gprrpvkyeedvnlgsgtravvscaeapnmkiignrierirsehaetwffdenhpyrtwa
yhgsyeaptqgsasslingvvrllskpwdvvtgvtgiamtdttpygqqrvfkekvdtrvp
dpqegtrqvmsmvsswlwkelgkhkrprvctkeefinkvrsnaalgaifeeekewktave
avndprfwalvdkerehhlrgecqscvynmmgkrekkqgefgkakgsraiwymwlgarfl
efealgflnedhwmgrensgggveglglqrlgyvleemsripggrmyaddtagwdtrisr
fdlenealitnqmekghralalaiikytyqnkvvkvlrpaekgktvmdiisrqdqrgsgq
vvtyalntftnlvvqlirnmeaeevlemqdlwllrrsekvtnwlqsngwdrlkrmavsgd
dcvvkpiddrfahalrflndmgkvrkdtqewkpstgwdnweevpfcshhfnklhlkdgrs
ivvpcrhqdeligrarvspgagwsiretaclaksyaqmwqllyfhrrdlrlmanaicssv
pvdwvptgrttwsihgkgewmttedmlvvwnrvwieendhmedktpvtkwtdipylgkre
dlwcgslighrprttwaenikntvnmvrriigdeekymdylst

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6i7pF (F:)
mgggtgetlgekwkarlnqmsalefysykksgitevcreearralkdgvatgghavsrgs
aklrwlvergylqpygkvidlgcgrggwsyyaatirkvqevkgytkggpgheepvlvqsy
gwnivrlksgvdvfhmaaepcdtllcdigesssspeveeartlrvlsmvgdwlekrpgaf
cikvlcpytstmmetlerlqrryggglvrvplsrnsthemywvsgaksntiksvsttsql
llgrmdgprrpvkyeedvnlgsgtravvscaeapnmkiignrierirsehaetwffdenh
pyrtwayhgsyeaptqgsasslingvvrllskpwdvvtgvtgiamtdttpygqqrvfkek
vdtrvpdpqegtrqvmsmvsswlwkelgkhkrprvctkeefinkvrsnaalgaifeeeke
wktaveavndprfwalvdkerehhlrgecqscvynmmgkrekkqgefgkakgsraiwymw
lgarflefealgflnedhwmgrensgggveglglqrlgyvleemsripggrmyaddtagw
dtrisrfdlenealitnqmekghralalaiikytyqnkvvkvlrpaekgktvmdiisrqd
qrgsgqvvtyalntftnlvvqlirnmeaeevlemqdlwllrrsekvtnwlqsngwdrlkr
mavsgddcvvkpiddrfahalrflndmgkvrkdtqewkpstgwdnweevpfcshhfnklh
lkdgrsivvpcrhqdeligrarvspgagwsiretaclaksyaqmwqllyfhrrdlrlman
aicssvpvdwvptgrttwsihgkgewmttedmlvvwnrvwieendhmedktpvtkwtdip
ylgkredlwcgslighrprttwaenikntvnmvrriigdeekymdylstqvrylgeegst
pgvlgssshhhhhh

    Sequence, based on observed residues (ATOM records):
    >6i7pF (F:)
etlgekwkarlnqmsalefysykksgitevcreearralkdgvatgghavsrgsaklrwl
vergylqpygkvidlgcgrggwsyyaatirkvqevkgytkggpgheepvlvqsygwnivr
lksgvdvfhmaaepcdtllcdigesssspeveeartlrvlsmvgdwlekrpgafcikvlc
pytstmmetlerlqrryggglvrvplsrnsthemywvsgaksntiksvsttsqlllgrmd
gprrpvkyeedvnlgsgtravvscaeapnmkiignrierirsehaetwffdenhpyrtwa
yhgsyeaptqgsasslingvvrllskpwdvvtgvtgiamtdttpygqqrvfkekvdtrvp
dpqegtrqvmsmvsswlwkelgkhkrprvctkeefinkvrsnaalgaifeeekewktave
avndprfwalvdkerehhlrgecqscvynmmgkrekkqgefgkakgsraiwymwlgarfl
efealgflnedhwmgrensgggveglglqrlgyvleemsripggrmyaddtagwdtrisr
fdlenealitnqmekghralalaiikytyqnkvvkvlrpaekgktvmdiisrqdqrgsgq
vvtyalntftnlvvqlirnmeaeevlemqdlwllrrsekvtnwlqsngwdrlkrmavsgd
dcvvkpiddrfahalrflndmgkvrkdtqewkpstgwdnweevpfcshhfnklhlkdgrs
ivvpcrhqdeligrarvspgagwsiretaclaksyaqmwqllyfhrrdlrlmanaicssv
pvdwvptgrttwsihgkgewmttedmlvvwnrvwieendhmedktpvtkwtdipylgkre
dlwcgslighrprttwaenikntvnmvrriigdeekymdylst